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Tripotassium Citrate Monohydrate
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Tripotassium Citrate Monohydrate USP is a pharmaceutical-grade potassium salt of citric acid, widely used for its alkalinizing, buffering, and chelating properties. It appears as a white crystalline powder and is highly soluble in water. This compound is primarily used to correct metabolic acidosis, act as a urinary alkalinizer, and serve as an additive in pharmaceutical, food, and industrial applications. The USP grade ensures compliance with United States Pharmacopeia standards, guaranteeing high purity and consistent quality.
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Tripotassium Citrate Monohydrate
Primary Uses
- Pharmaceutical Industry:
- Used as an alkalinizing agent in treatments for kidney stone prevention, urinary tract infections, and metabolic acidosis.
- Incorporated in effervescent tablets and powders to provide potassium supplementation and urine alkalization.
- Acts as a buffering agent in pharmaceutical formulations to stabilize pH.
- Food Industry:
- Serves as a food additive to regulate acidity and as an emulsifier in beverages, dairy products, and processed foods
- Used as a sequestrant and stabilizer in canned fruits and jams.
Secondary Uses
- Cosmetics and Personal Care
- Used in skin care products as a pH adjuster and buffering agent.
- Industrial Applications:
- Functions as a chelating agent in cleaning products and detergents to bind metal ions and improve efficacy.
- Agriculture:
- Occasionally used in fertilizers as a potassium source and pH modifier.
KEY PRODUCT FEATURES
1. Basic Key Attributes
- Chemical Name (IUPAC): Tripotassium 2-hydroxypropane-1,2,3-tricarboxylate monohydrate
- Common/Trade Name: Tripotassium Citrate Monohydrate USP
- CAS Number: 6100-05-6
- HS Code: 2918.16.00
- Synonyms: Potassium citrate monohydrate, tripotassium citrate
2. Physical & Chemical Properties
- Physical State: White crystalline powder or granules
- Color & Odor: White; odorless
- Melting Point: Approx. 180 °C (decomposes)
- Solubility: Highly soluble in water; insoluble in alcohol
- pH: Alkaline aqueous solution (pH ~9.0)
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under normal handling
- Toxicity: Low toxicity; considered safe when used as directed
- Exposure Limits: No specific occupational limits; standard good practices apply
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area, away from moisture and incompatible substances
- Container Type: Sealed plastic bags or drums, moisture-proof packaging preferred
- Shelf Life: 24 months under recommended storage conditions
- Handling Precautions: Avoid dust generation and exposure to moisture
5. Regulatory & Compliance Attributes
- Complies with United States Pharmacopeia (USP) standards
- Manufactured under Good Manufacturing Practices (GMP)
- Listed on major chemical inventories including TSCA and REACH
- Approved for use in food, pharmaceutical, and cosmetic applications as per regulatory requirements
6. Environmental & Health Impact
- Biodegradability: Biodegradable under aerobic conditions
- Ecotoxicity: Low toxicity to aquatic organisms
- Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS
Safety Handling Precautions
- PPE Required: Gloves, dust mask, and eye protection recommended during handling
- Handling Guidelines: Use adequate ventilation to minimize dust exposure
- Storage Measures: Keep containers sealed and dry
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if respiratory symptoms develop
- Skin Contact: Wash with soap and water
- Eye Contact: Rinse with plenty of water for at least 15 minutes; seek medical help if irritation persists
- Ingestion: Rinse mouth; seek medical advice if adverse effects occur
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Use water spray, foam, or dry chemical extinguishers
- Hazardous Combustion Products: May emit carbon oxides on decomposition
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