Vitamin B3 (Niacin)

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Vitamin B3 Niacin, also known as Niacin or Nicotinic Acid, is a water-soluble vitamin essential for energy metabolism and enzymatic reactions in the body. It plays a key role in the synthesis of coenzymes NAD and NADP, which are critical for cellular respiration and DNA repair. Niacin is widely used in pharmaceuticals, nutraceuticals, food fortification, and animal nutrition to prevent niacin deficiency and support overall health.

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Categories: Active Pharmaceutical Ingredients (APIs), Nutrient Supplements Tags: Food & Beverage Industry, Niacin, Nutraceuticals, Nutritional supplement, Pharmaceuticals, Vitamin B3, Water-soluble vitamin

Description

Table of Contents

Vitamin B3 (Niacin)

Primary Uses

Pharmaceutical Industry

Nutritional Supplement: Used in tablets, capsules, and injections to treat and prevent niacin deficiency, including pellagra.
Lipid Regulation: Utilized as a therapeutic agent to improve cholesterol levels and reduce cardiovascular risk.

Food & Beverage Industry

Fortification Agent: Added to cereals, flour, and beverages to enhance nutritional value and prevent deficiencies in populations.

Nutraceuticals & Dietary Supplements

Incorporated in multivitamin and B-complex supplements for energy metabolism, skin health, and neurological function.

Secondary Uses

Animal Nutrition

Feed Additive: Used in livestock and poultry feeds to promote growth, improve feed efficiency, and prevent deficiency.

Cosmetics

Ingredient in skin care products for its role in improving skin elasticity and reducing redness.

Research & Development

Applied in studies related to metabolic disorders, cardiovascular health, and vitamin therapy.

KEY PRODUCT FEATURES

1. Basic Identification Attributes

Chemical Name (IUPAC): Pyridine-3-carboxylic acid
Common/Trade Name: Niacin, Vitamin B3
CAS Number: 59-67-6
HS Code: 2922.49.00
Synonyms: Nicotinic acid, Vitamin PP, Niacin

2. Physical & Chemical Properties

Physical State: White to pale yellow crystalline powder
Color & Odor: White to pale yellow; odorless or slight acidic odor
Solubility: Soluble in water; sparingly soluble in alcohol
Melting Point: 237 °C (decomposes)
Density: Approx. 1.5 g/cm³

3. Safety & Hazard Attributes

GHS Classification: Not classified as hazardous under normal use
Toxicity: Low toxicity; safe within recommended doses
Exposure Limits: No specific occupational exposure limits established

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry, well-ventilated area away from light and moisture
Container Type: Sealed containers or bags
Shelf Life: 24 months under proper storage conditions
Handling Precautions: Avoid dust formation and exposure to moisture

5. Regulatory & Compliance Attributes

Complies with USP, BP, and other pharmacopeial standards
Manufactured under GMP to ensure consistent quality and safety
Approved for pharmaceuticals, dietary supplements, and food fortification
Meets international regulatory requirements

6. Environmental & Health Impact

Biodegradability: Biodegradable under normal environmental conditions
Ecotoxicity: Low environmental impact
Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required: Gloves and dust mask recommended during handling
Handling Guidelines: Use adequate ventilation; avoid inhalation of dust
Storage Measures: Keep containers tightly closed and dry

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if irritation persists
Skin Contact: Wash thoroughly with soap and water
Eye Contact: Flush eyes with water for 15 minutes; seek medical advice if irritation continues
Ingestion: Rinse mouth; obtain medical advice if large amounts ingested

Firefighting Measures

Fire Hazards: Combustible solid
Extinguishing Media: Use water spray, foam, or dry chemical extinguishers
Hazardous Combustion Products: May produce carbon oxides and nitrogen oxides upon combustion