Vitamin B3 (Nicotinamide) Amaris Chemicals
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Vitamin B3 ( Niacin) Amaris Chemicals
Vitamin B3 (Niacin)
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Vitamin B3 (Nicotinamide)

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Vitamin B3 Nicotinamide, also known as Niacinamide, is a water-soluble amide form of vitamin B3. It plays a crucial role in cellular energy production and DNA repair by serving as a precursor for coenzymes NAD and NADP. Nicotinamide is preferred in many pharmaceutical and cosmetic applications due to its stability and lower side-effect profile compared to niacin. It is widely used in pharmaceuticals, nutraceuticals, cosmetics, and food fortification.

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Description

Vitamin B3 (Nicotinamide)

Primary Uses 

  1. Pharmaceutical Industry
  • Nutritional Supplement: Used to treat and prevent vitamin B3 deficiency and pellagra without causing flushing side effects.
  • Therapeutic Agent: Applied in skin-related treatments and as an adjunct in managing certain neurological and metabolic disorders.
  1. Cosmetic Industry
  • Skin Care Ingredient: Utilized in creams, lotions, and serums for its anti-inflammatory, anti-aging, and skin-brightening properties.
  1. Food & Beverage Industry
  • Fortification Agent: Added to fortified foods and dietary supplements to improve nutritional content.

Secondary Uses

  1. Animal Nutrition
  • Feed Supplement: Used to enhance growth, metabolism, and overall health in livestock.
  1. Research & Development
  • Utilized in biomedical research on metabolism, skin health, and vitamin therapy.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): Pyridine-3-carboxamide
  • Common/Trade Name: Nicotinamide, Niacinamide, Vitamin B3
  • CAS Number: 98-92-0
  • HS Code: 2922.49.00
  • Synonyms: Niacinamide, Nicotinic acid amide

2. Physical & Chemical Properties

  • Physical State: White crystalline powder
  • Color & Odor: White; odorless
  • Solubility: Soluble in water; slightly soluble in alcohol
  • Melting Point: 128–131 °C
  • Density: Approx. 1.4 g/cm³

3. Safety & Hazard Attributes

  • GHS Classification: Not classified as hazardous under normal conditions
  • Toxicity: Low toxicity; safe within recommended doses
  • Exposure Limits: No established occupational exposure limits

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry, well-ventilated area protected from light and moisture
  • Container Type: Sealed containers or bags
  • Shelf Life: 24 months under proper storage conditions
  • Handling Precautions: Avoid dust formation; minimize exposure to moisture

5. Regulatory & Compliance Attributes

  • Complies with USP, BP, and other pharmacopeial standards
  • Manufactured under GMP to ensure consistent quality and safety
  • Approved for use in pharmaceuticals, dietary supplements, cosmetics, and food fortification
  • Meets international regulatory requirements

6. Environmental & Health Impact

  • Biodegradability: Biodegradable and environmentally safe
  • Ecotoxicity: Low environmental hazard
  • Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Gloves and dust mask recommended
  • Handling Guidelines: Use adequate ventilation; avoid inhalation of dust
  • Storage Measures: Keep containers tightly closed and dry

First Aid Measures

  • Inhalation: Remove to fresh air; seek medical attention if irritation occurs
  • Skin Contact: Wash with soap and water
  • Eye Contact: Flush with water for 15 minutes; seek medical help if irritation persists
  • Ingestion: Rinse mouth; obtain medical advice if large amounts ingested

Firefighting Measures

  • Fire Hazards: Combustible solid
  • Extinguishing Media: Water spray, foam, or dry chemical extinguishers
  • Hazardous Combustion Products: Carbon oxides and nitrogen oxides may form upon combustion

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