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Vitamin B1 (Mono Nitrate BP)
Vitamin B1 Mononitrate BP is a stable, synthetic derivative of vitamin B1 (thiamine) used extensively in pharmaceutical, nutraceutical, and food fortification applications. It serves as an essential nutrient involved in carbohydrate metabolism and nervous system function. The mononitrate form offers enhanced stability and bioavailability compared to pure thiamine, making it ideal for inclusion in tablets, capsules, powders, and fortified food products.
Vitamin B1 (Mono Nitrate BP)
Primary Uses
- Pharmaceutical Industry
- Nutritional Supplement: Used in oral tablets, capsules, and injectables to prevent or treat thiamine deficiency and related disorders such as beriberi and Wernicke-Korsakoff syndrome.
- Neurological Support: Incorporated in formulations supporting nerve health and energy metabolism.
- Food & Beverage Industry
- Fortification Agent: Added to flour, cereals, beverages, and other food products to enhance nutritional content and prevent deficiency.
- Nutraceuticals & Dietary Supplements
- Included in multivitamin and B-complex supplements to support overall health and metabolic function.
Secondary Uses
- Animal Nutrition
- Feed Additive: Supplemented in animal feed to improve growth, appetite, and neurological health in livestock and pets.
- Cosmetic Industry
- Skin Health: Occasionally used in topical formulations for promoting skin vitality and repair, though limited.
- Research & Development
- Used in biochemical and nutritional studies involving vitamin B1 metabolism and deficiency.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium mononitrate
- Common/Trade Name: Vitamin B1 Mononitrate BP
- CAS Number: 532-43-4
- HS Code: 2936.21.00
- Synonyms: Thiamine mononitrate, vitamin B1 nitrate
2. Physical & Chemical Properties
- Physical State: Fine, white to off-white crystalline powder
- Color & Odor: White to off-white; odorless or faint characteristic odor
- Solubility: Soluble in water and alcohol
- Melting Point: 210-214 °C (decomposes)
- Density: Approx. 1.5 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under normal use
- Toxicity: Low toxicity; safe within recommended dosages
- Exposure Limits: No specific occupational exposure limits established
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area away from light and moisture
- Container Type: Sealed bags or containers, moisture-proof packaging preferred
- Shelf Life: 24 months under proper storage conditions
- Handling Precautions: Avoid dust formation and inhalation; use PPE if necessary
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Manufactured under GMP conditions for pharmaceutical grade quality
- Approved for use in food fortification, dietary supplements, and pharmaceuticals
- Meets international regulatory requirements for vitamin B1 products
6. Environmental & Health Impact
- Biodegradability: Biodegradable and environmentally safe under normal conditions
- Ecotoxicity: Low environmental risk
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves and dust mask recommended during handling
- Handling Guidelines: Use in well-ventilated areas to minimize dust exposure
- Storage Measures: Keep container tightly closed and dry
First Aid Measures
- Inhalation: Move to fresh air; seek medical advice if symptoms persist
- Skin Contact: Wash with soap and water
- Eye Contact: Flush with water for 15 minutes; seek medical help if irritation persists
- Ingestion: Rinse mouth; seek medical advice if large amounts ingested
Firefighting Measures
- Fire Hazards: Not highly flammable but combustible
- Extinguishing Media: Use water spray, foam, or dry chemical extinguishers
- Hazardous Combustion Products: May produce carbon oxides and nitrogen oxides on burning
Related products
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Doxycycline Hyclate BP
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Guaiphenesin BP
Guaiphenesin BP is a white crystalline powder or granules with a faint characteristic odor, classified as an expectorant used primarily in pharmaceutical formulations to relieve chest congestion. It works by loosening and thinning mucus in the airways, making it easier to cough up and clear from the respiratory tract. It is widely utilized in cough syrups, tablets, and cold remedies. Recognized for its mucolytic and muscle-relaxant properties, Guaiphenesin is included in both prescription and over-the-counter medications worldwide.
Hydrocortisone Acetate
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Hydrocortisone Base BP 93 Micro
Hydrocortisone Base BP 93 Micro is a highly purified, micronized form of hydrocortisone base compliant with British Pharmacopoeia (BP) standards. It is a white to off-white fine powder designed for enhanced solubility and bioavailability in pharmaceutical formulations. As a corticosteroid hormone analog, it exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic activities. The micronized particle size (~93 microns) facilitates improved dispersion in topical, injectable, and oral dosage forms.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Piperazine Citrate BP
Piperazine Citrate BP is a pharmaceutical-grade anthelmintic compound used primarily for the treatment of intestinal worm infections, especially ascariasis (roundworms) and enterobiasis (pinworms). It works by paralyzing the worms, allowing them to be expelled naturally from the body through bowel movements. Piperazine Citrate is included in the British Pharmacopoeia (BP) and is known for its safety, efficacy, and wide use in both human and veterinary medicine.
