Tripotassium Citrate Monohydrate usp Amaris Chemicals
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PHARMACEUTICAL GRADE USP GRADE

Tripotassium Citrate Monohydrate

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Tripotassium Citrate Monohydrate USP is a pharmaceutical-grade potassium salt of citric acid, widely used for its alkalinizing, buffering, and chelating properties. It appears as a white crystalline powder and is highly soluble in water. This compound is primarily used to correct metabolic acidosis, act as a urinary alkalinizer, and serve as an additive in pharmaceutical, food, and industrial applications. The USP grade ensures compliance with United States Pharmacopeia standards, guaranteeing high purity and consistent quality.

 

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Description

Tripotassium Citrate Monohydrate

Primary Uses

  1. Pharmaceutical Industry:
  • Used as an alkalinizing agent in treatments for kidney stone prevention, urinary tract infections, and metabolic acidosis.
  • Incorporated in effervescent tablets and powders to provide potassium supplementation and urine alkalization.
  • Acts as a buffering agent in pharmaceutical formulations to stabilize pH.
  1. Food Industry:
  • Serves as a food additive to regulate acidity and as an emulsifier in beverages, dairy products, and processed foods
  • Used as a sequestrant and stabilizer in canned fruits and jams.

Secondary Uses

  1. Cosmetics and Personal Care
  • Used in skin care products as a pH adjuster and buffering agent.
  1. Industrial Applications:
  • Functions as a chelating agent in cleaning products and detergents to bind metal ions and improve efficacy.
  1. Agriculture:
  • Occasionally used in fertilizers as a potassium source and pH modifier.
KEY PRODUCT FEATURES

1. Basic Key Attributes

  • Chemical Name (IUPAC): Tripotassium 2-hydroxypropane-1,2,3-tricarboxylate monohydrate
  • Common/Trade Name: Tripotassium Citrate Monohydrate USP
  • CAS Number: 6100-05-6
  • HS Code: 2918.16.00
  • Synonyms: Potassium citrate monohydrate, tripotassium citrate

2. Physical & Chemical Properties

  • Physical State: White crystalline powder or granules
  • Color & Odor: White; odorless
  • Melting Point: Approx. 180 °C (decomposes)
  • Solubility: Highly soluble in water; insoluble in alcohol
  • pH: Alkaline aqueous solution (pH ~9.0)

3. Safety & Hazard Attributes

  • GHS Classification: Not classified as hazardous under normal handling
  • Toxicity: Low toxicity; considered safe when used as directed
  • Exposure Limits: No specific occupational limits; standard good practices apply

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry, well-ventilated area, away from moisture and incompatible substances
  • Container Type: Sealed plastic bags or drums, moisture-proof packaging preferred
  • Shelf Life: 24 months under recommended storage conditions
  • Handling Precautions: Avoid dust generation and exposure to moisture

5. Regulatory & Compliance Attributes

  • Complies with United States Pharmacopeia (USP) standards
  • Manufactured under Good Manufacturing Practices (GMP)
  • Listed on major chemical inventories including TSCA and REACH
  • Approved for use in food, pharmaceutical, and cosmetic applications as per regulatory requirements

6. Environmental & Health Impact

  • Biodegradability: Biodegradable under aerobic conditions
  • Ecotoxicity: Low toxicity to aquatic organisms
  • Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Gloves, dust mask, and eye protection recommended during handling
  • Handling Guidelines: Use adequate ventilation to minimize dust exposure
  • Storage Measures: Keep containers sealed and dry

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if respiratory symptoms develop
  • Skin Contact: Wash with soap and water
  • Eye Contact: Rinse with plenty of water for at least 15 minutes; seek medical help if irritation persists
  • Ingestion: Rinse mouth; seek medical advice if adverse effects occur

Firefighting Measures

  • Fire Hazards: Non-flammable
  • Extinguishing Media: Use water spray, foam, or dry chemical extinguishers
  • Hazardous Combustion Products: May emit carbon oxides on decomposition

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