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Simethicone Emulsion
Simethicone Emulsion is a medical-grade, anti-foaming agent composed of polydimethylsiloxane and silicon dioxide in an emulsified form. Designed to reduce gas bubbles in the gastrointestinal tract, it provides rapid relief from bloating and discomfort. The emulsion formulation enhances bioavailability and mixing with bodily fluids.
Simethicone Emulsion
Primary Uses
- Gastrointestinal Treatments
- Immediate relief of gas pain and bloating
- Pre-treatment for abdominal diagnostic procedures (X-ray, endoscopy)
- Management of functional dyspepsia
- Adjunct in GERD therapy
- Infant Care
- Treatment of colic and infant gas discomfort
- Prevention of feeding-related gas accumulation
Secondary Uses
- Veterinary Medicine
- Relief of ruminant bloat in cattle
- Treatment of gas accumulation in horses
- Pharmaceutical Manufacturing
- Defoaming agent in fermentation processes
- Additive in antacid formulations
1. Basic Identification Attributes
- Chemical Name: Polymethylsiloxane hydrated silica
- CAS Number: 8050-81-5
- INCI Name: Dimethicone
- HS Code: 3910.00.00
- Synonyms: Activated dimethicone, anti-flatulent agent
2. Physical & Chemical Properties
- Physical State: Milky white emulsion
- Color: White to off-white
- Odor: Characteristic mild silicone odor
- Viscosity: 100-500 cps
- pH: 6.0-7.5
- Density: 1.00-1.05 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Non-hazardous
- Toxicity: Non-toxic (LD50 >5000 mg/kg)
- Exposure Limits: No occupational exposure limits established
4. Storage & Handling Attributes
- Storage Conditions:
- Store at 15-30°C
- Protect from freezing
- Container Type: HDPE bottles with phenolic caps
- Shelf Life: 24 months unopened
- Handling Precautions:
- Avoid prolonged skin contact
5. Regulatory & Compliance Attributes
- Complies with:
- USP/NF monograph standards
- FDA 21 CFR 332.30
- EP 10.0 requirements
6. Environmental & Health Impact
- Biodegradability: Not readily biodegradable
- Ecotoxicity: Low environmental impact
Safety Handling Precautions
- PPE Required: Safety glasses, nitrile gloves
- Handling Guidelines: Standard laboratory practices
First Aid Measures
- Eye Contact: Rinse with water for 15 minutes
- Ingestion: No treatment needed (non-toxic)
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Use appropriate media for surrounding fire
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