Acidulants
Antioxidants
Nutraceutical Ingredients (food)
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Fragrances and Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Chromatography Chemicals
Spectroscopy Reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Fresh Herbs
Ground Spices
Whole Spices
Spice Blends
Dried Herbs
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders
Chloropheniramine Maleate
Whatsapp Order
Chloropheniramine Maleate is a first-generation alkylamine antihistamine used primarily to relieve allergy symptoms by blocking H1 histamine receptors. It appears as a white or off-white crystalline powder, freely soluble in water and alcohol. Known for rapid onset and moderate duration of action, it’s widely formulated in pharmaceuticals. It also exhibits mild anticholinergic and sedative effects.
Description
Chloropheniramine Maleate
Primary Uses
Pharmaceuticals
- Active ingredient in oral tablets, capsules, and syrups for treatment of:
- Allergic rhinitis (hay fever)
- Urticaria (hives)
- Allergic conjunctivitis
- Anaphylaxis adjunct therapy
- Common cold symptom relief (sneezing, runny nose)
- Used in combination cold, flu, and allergy medications with decongestants, analgesics, and cough suppressants.
- Injectable forms used for rapid allergy symptom relief in emergency or clinical settings.
Veterinary Medicine
- Treatment of pruritus and allergic reactions in animals including dogs and cats.
Pharmacology & Toxicology Research
- Widely used in lab research to study histamine H1 receptor antagonism and allergy mechanisms.
Secondary Uses
Cosmetics & Topical Preparations
- Incorporated in anti-itch creams, lotions, or gels for localized relief of itching and allergic skin reactions (limited use due to systemic absorption concerns).
Over-the-Counter (OTC) Products
- Included in OTC antihistamine formulations targeting mild allergy symptoms and seasonal hay fever relief.
Formulation Studies
- Used by pharmaceutical companies in drug formulation development for evaluating bioavailability, stability, and efficacy of antihistamines.
Analytical Reference Standard
- Employed in quality control laboratories as a reference standard to verify purity and potency of antihistamine drugs.
KEY PRODUCT FEATURES
- Basic Identification Attributes
- Chemical Name (IUPAC): 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine maleate
- Common/Trade Name: Chlorpheniramine Maleate
- CAS Number: 132-22-9
- HS Code: 2933.69.90
- Molecular Formula: C16H19ClN2 · C4H4O4
- Synonyms: CPM, Chlorphenamine Maleate
- Physical & Chemical Properties
- Physical State: White or off-white crystalline powder
- Melting Point: 125–130°C
- Solubility: Freely soluble in water and ethanol; slightly soluble in chloroform and ether
- Stability: Stable under normal conditions; sensitive to light and moisture
- Safety & Hazard Attributes
- Hazard Class (GHS): Harmful if swallowed; may cause drowsiness or dizziness
- NFPA Ratings: Health 2, Flammability 1, Reactivity 0
- Exposure Limits: No specific limits; dust exposure to be minimized
- Toxicity: Moderate toxicity; overdose can cause anticholinergic effects and CNS depression
- Storage & Handling Attributes
- Store in cool, dry, dark place; use airtight containers
- Shelf life: 3–5 years
- Use PPE to avoid inhalation and skin contact
- Regulatory & Compliance Attributes
- Included in USP, BP, EP
- FDA approved as antihistamine active pharmaceutical ingredient
- Registered under REACH and other international regulations
- Environmental & Health Impact
- Low ecotoxicity; biodegradable; low bioaccumulation potential
- Not classified as carcinogenic or mutagenic
SAFETY HANDLING PRECAUTIONS
-
Safety Handling Precautions
- Wear gloves, dust masks, goggles
- Avoid inhalation, skin and eye contact
- Use in well-ventilated areas
First Aid Measures
- Inhalation: Fresh air, medical attention if symptoms persist
- Skin: Wash with soap and water, seek care if irritated
- Eyes: Flush with water, seek medical help if needed
- Ingestion: Do not induce vomiting, seek urgent medical attention
Firefighting Measures
- Combustible; use dry chemical, foam, CO₂
- Wear full protective gear
- Avoid inhalation of combustion products (HCl, nitrogen oxides)
Related products
Carbocisteine AJI 92
Carbocisteine AJI 92 is a high-purity pharmaceutical-grade amino acid derivative, chemically known as S-carboxymethyl-L-cysteine. It is a white to off-white crystalline powder with a slightly sulfurous odor and is freely soluble in water. Carbocisteine functions primarily as a mucolytic agent—reducing the viscosity of mucus and promoting expectoration in respiratory tract infections. The "AJI 92" specification refers to its compliance with the purity standards established by Ajinomoto's amino acid quality benchmarks, ensuring it meets stringent pharmaceutical-grade quality control for active pharmaceutical ingredients (APIs). It is widely used in oral syrups, tablets, and granules in both human and veterinary medicine.
Chloramphenicol Palmitate Micronised
Chloramphenicol Palmitate Micronised is a micronized, lipophilic ester derivative of chloramphenicol, designed for improved solubility and bioavailability compared to the parent drug. It appears as a fine, white to off-white powder with enhanced surface area due to micronization. This antibiotic is widely used for oral formulations, particularly pediatric suspensions, due to its palatability and controlled release properties. Chloramphenicol Palmitate exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. Its ester form offers better stability and reduced bitterness, making it a preferred choice in pharmaceutical preparations.
Dicyclomine Hydrochloride
Dicyclomine Hydrochloride is an anticholinergic and antispasmodic agent used primarily to relieve smooth muscle spasms in the gastrointestinal tract. It works by blocking muscarinic receptors, thereby reducing muscle contractions and spasms, which helps alleviate symptoms of irritable bowel syndrome (IBS) and other functional bowel disorders. It is commonly available in oral tablets, capsules, and injectable formulations.
Diphenhydramine HCL BP
Diphenhydramine HCL BP is a first-generation antihistamine with potent anticholinergic, sedative, and antiemetic properties. It is commonly used to relieve symptoms associated with allergies, hay fever, the common cold, and motion sickness. Diphenhydramine HCL is a white crystalline powder, highly soluble in water, making it suitable for oral, topical, and injectable pharmaceutical formulations. Due to its ability to cross the blood-brain barrier, it causes sedation and is often used as a sleep aid and for managing Parkinson’s disease symptoms.
Ellagic Acid
Ellagic Acid is a naturally occurring polyphenolic compound found in numerous fruits, nuts, and vegetables such as pomegranates, strawberries, raspberries, walnuts, and cranberries. It is a potent antioxidant known for its ability to scavenge free radicals and chelate metal ions. Due to its significant anti-inflammatory, anti-carcinogenic, and anti-viral properties, Ellagic Acid has gained extensive interest in pharmaceutical, nutraceutical, cosmetic, and food industries. It appears as a yellow to light brown crystalline powder, insoluble in water but soluble in organic solvents like ethanol and DMSO.
Hydrocortisone Acetate
Hydrocortisone Acetate is a synthetic corticosteroid ester derived from hydrocortisone (cortisol). It is a white to off-white crystalline powder, practically insoluble in water but soluble in alcohol and acetone. This compound exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic properties, making it widely used in pharmaceutical and dermatological formulations. Hydrocortisone Acetate acts by modulating gene expression to reduce the production of inflammatory mediators, thereby alleviating symptoms in various inflammatory and autoimmune conditions.
Ichthammol BP98
Ichthammol BP98, also known as ammonium bituminosulfonate, is a dark brown to black, viscous, sulfur-rich, semi-solid substance derived from the distillation of shale or bituminous rocks. It has a characteristic tar-like odor and is highly valued in pharmaceutical and dermatological applications for its anti-inflammatory, antiseptic, antipruritic (anti-itch), and keratolytic properties. Ichthammol penetrates deeply into the skin and soft tissues, helping to alleviate inflammation and promote healing. It is widely used in topical preparations for treating skin conditions such as eczema, psoriasis, boils, abscesses, and other dermatological infections.
Metronidazole BP
Metronidazole BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
