Preservatives(food)
Flavors
Acidulants
Sweeteners
Antioxidants
Colorants(food)
Nutraceutical Ingredients (food)
Nutrient Supplements
Emulsifiers
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Oils
Carrier Oills
Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Solvents(lab)
Chromatography Chemicals
Spectroscopy Reagents
microbiology-and-cell-culture-reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances (Cleaning)
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders
Chloropheniramine Maleate
Chloropheniramine Maleate is a first-generation alkylamine antihistamine used primarily to relieve allergy symptoms by blocking H1 histamine receptors. It appears as a white or off-white crystalline powder, freely soluble in water and alcohol. Known for rapid onset and moderate duration of action, it’s widely formulated in pharmaceuticals. It also exhibits mild anticholinergic and sedative effects.
Chloropheniramine Maleate
Primary Uses
- Pharmaceuticals
- Active ingredient in oral tablets, capsules, and syrups for treatment of:
- Allergic rhinitis (hay fever)
- Urticaria (hives)
- Allergic conjunctivitis
- Anaphylaxis adjunct therapy
- Common cold symptom relief (sneezing, runny nose)
- Used in combination cold, flu, and allergy medications with decongestants, analgesics, and cough suppressants.
- Injectable forms used for rapid allergy symptom relief in emergency or clinical settings.
- Veterinary Medicine
- Treatment of pruritus and allergic reactions in animals including dogs and cats.
- Pharmacology & Toxicology Research
- Widely used in lab research to study histamine H1 receptor antagonism and allergy mechanisms.
Secondary Uses
- Cosmetics & Topical Preparations
- Incorporated in anti-itch creams, lotions, or gels for localized relief of itching and allergic skin reactions (limited use due to systemic absorption concerns).
- Over-the-Counter (OTC) Products
- Included in OTC antihistamine formulations targeting mild allergy symptoms and seasonal hay fever relief.
- Formulation Studies
- Used by pharmaceutical companies in drug formulation development for evaluating bioavailability, stability, and efficacy of antihistamines.
- Analytical Reference Standard
- Employed in quality control laboratories as a reference standard to verify purity and potency of antihistamine drugs.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine maleate
- Common/Trade Name: Chlorpheniramine Maleate
- CAS Number: 132-22-9
- HS Code: 2933.69.90
- Molecular Formula: C16H19ClN2 · C4H4O4
- Synonyms: CPM, Chlorphenamine Maleate
2. Physical & Chemical Properties
- Physical State: White or off-white crystalline powder
- Melting Point: 125–130°C
- Solubility: Freely soluble in water and ethanol; slightly soluble in chloroform and ether
- Stability: Stable under normal conditions; sensitive to light and moisture
3. Safety & Hazard Attributes
- Hazard Class (GHS): Harmful if swallowed; may cause drowsiness or dizziness
- NFPA Ratings: Health 2, Flammability 1, Reactivity 0
- Exposure Limits: No specific limits; dust exposure to be minimized
- Toxicity: Moderate toxicity; overdose can cause anticholinergic effects and CNS depression
4. Storage & Handling Attributes
- Store in cool, dry, dark place; use airtight containers
- Shelf life: 3–5 years
- Use PPE to avoid inhalation and skin contact
5. Regulatory & Compliance Attributes
- Included in USP, BP, EP
- FDA approved as antihistamine active pharmaceutical ingredient
- Registered under REACH and other international regulations
6. Environmental & Health Impact
- Low ecotoxicity; biodegradable; low bioaccumulation potential
- Not classified as carcinogenic or mutagenic
Safety Handling Precautions
- Wear gloves, dust masks, goggles
- Avoid inhalation, skin and eye contact
- Use in well-ventilated areas
First Aid Measures
- Inhalation: Fresh air, medical attention if symptoms persist
- Skin: Wash with soap and water, seek care if irritated
- Eyes: Flush with water, seek medical help if needed
- Ingestion: Do not induce vomiting, seek urgent medical attention
Firefighting Measures
- Combustible; use dry chemical, foam, CO₂
- Wear full protective gear
- Avoid inhalation of combustion products (HCl, nitrogen oxides)
Related products
Cetirizine Hydrochloride
Cetirizine Hydrochloride is a widely used second-generation antihistamine effective for treating allergic conditions such as allergic rhinitis, chronic urticaria, and other allergy symptoms. It is the hydrochloride salt form of cetirizine, existing as a white to off-white crystalline powder with a slightly bitter taste. Cetirizine HCl acts by selectively blocking peripheral H1 histamine receptors, thereby reducing allergic symptoms without significant sedation or central nervous system depression. It is commonly formulated into tablets, syrups, and capsules as an active pharmaceutical ingredient.
Hydrocortisone Acetate
Hydrocortisone Acetate is a synthetic corticosteroid ester derived from hydrocortisone (cortisol). It is a white to off-white crystalline powder, practically insoluble in water but soluble in alcohol and acetone. This compound exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic properties, making it widely used in pharmaceutical and dermatological formulations. Hydrocortisone Acetate acts by modulating gene expression to reduce the production of inflammatory mediators, thereby alleviating symptoms in various inflammatory and autoimmune conditions.
Ichthammol BP98
Ichthammol BP98, also known as ammonium bituminosulfonate, is a dark brown to black, viscous, sulfur-rich, semi-solid substance derived from the distillation of shale or bituminous rocks. It has a characteristic tar-like odor and is highly valued in pharmaceutical and dermatological applications for its anti-inflammatory, antiseptic, antipruritic (anti-itch), and keratolytic properties. Ichthammol penetrates deeply into the skin and soft tissues, helping to alleviate inflammation and promote healing. It is widely used in topical preparations for treating skin conditions such as eczema, psoriasis, boils, abscesses, and other dermatological infections.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Metronidazole BP
Metronidazole BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Miconazole Nitrate BP
Miconazole Nitrate BP is a high-purity, pharmaceutical-grade antifungal agent conforming to British Pharmacopoeia (BP) specifications. It is widely used in the formulation of topical and oral pharmaceutical products for the treatment of fungal infections caused by dermatophytes and yeasts, including Candida species. Miconazole Nitrate functions by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes, leading to cell death.
This white to off-white crystalline powder is highly effective and exhibits broad-spectrum antifungal and some antibacterial activity. It is commonly utilized in creams, ointments, powders, and gel formulations.
Neomycin Sulphate BP Oral
Neomycin Sulphate BP Oral is an aminoglycoside antibiotic derived from Streptomyces fradiae. It is used primarily for treating infections caused by susceptible aerobic gram-negative and some gram-positive bacteria. The oral form is especially utilized for intestinal antisepsis, to reduce bacterial flora before gastrointestinal surgery, or to treat hepatic encephalopathy by decreasing ammonia-producing bacteria in the gut. It is available in powder or tablet form conforming to British Pharmacopoeia (BP) standards, ensuring high purity and efficacy.
