EDTA Disodium Salt

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EDTA Disodium Salt (Ethylenediaminetetraacetic acid disodium salt) is a widely used chelating agent that binds metal ions to form stable complexes. It effectively sequesters divalent and trivalent metal ions such as calcium, magnesium, iron, and heavy metals, preventing their participation in unwanted chemical reactions. This property makes it essential in a wide range of industrial, pharmaceutical, cosmetic, agricultural, and water treatment applications. The disodium salt form offers excellent water solubility and is often used in neutral to slightly alkaline systems.

Description

EDTA Disodium Salt Uses

Primary Uses 
  1. Water Treatment & Industrial Cleaning

  • Used extensively to chelate metal ions in boiler feedwater and cooling water systems to prevent scale formation and corrosion.

  • Acts as a metal ion scavenger in detergents and industrial cleaners to improve cleaning efficiency.

  • Prevents discoloration and deposits caused by metal ions in pulp and paper processing.

  1. Pharmaceuticals & Medicine

  • Employed as a chelating agent to reduce metal-induced oxidative degradation in formulations.

  • Used in chelation therapy to treat heavy metal poisoning by binding and facilitating metal excretion.

  • Stabilizes active ingredients in injectable and topical drug formulations.

  1. Cosmetics & Personal Care

  • Added to shampoos, lotions, creams, and soaps to bind metal ions that cause product degradation and spoilage.

  • Improves foam stability and texture in cleansing products by softening water hardness.

  • Enhances product shelf life by preventing color changes and rancidity.

  1. Food Industry

  • Used as a food additive (E385) to preserve color, flavor, and texture by binding metal ions that catalyze oxidation.

  • Commonly used in canned foods, beverages, and processed products to enhance stability.

  1. Agriculture & Horticulture

  • Serves as a micronutrient chelator to improve bioavailability of trace metals like iron, zinc, and manganese in fertilizers and foliar sprays.

  • Prevents metal ion precipitation and enhances nutrient uptake in plants.

 

Secondary Uses 
  1. Analytical Chemistry

  • Used in complexometric titrations to determine metal ion concentrations.

  1. Textile Industry

  • Functions as a stabilizer and metal ion scavenger to prevent color fading and fabric degradation.

  1. Photography

Utilized in photographic developers to control metal ion interference.

PRODUCT KEY FEATURES
  1. Basic Identification Attributes

  • Chemical Name (IUPAC): Disodium 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate

  • Common/Trade Name: EDTA Disodium Salt

  • CAS Number: 139-33-3

  • HS Code: 2922.49.00

  • Molecular Formula: C₁₀H₁₄N₂Na₂O₈

  • Synonyms:

    • Ethylenediaminetetraacetic acid disodium salt

    • EDTA-2Na

    • Disodium EDTA

    • Versenate Sodium

  1. Physical & Chemical Properties

  • Physical State: White crystalline powder or granules

  • Color & Odor: White; odorless

  • pH (1% aqueous solution): Approximately 4.5–5.5

  • Solubility: Freely soluble in water; insoluble in ethanol and non-polar solvents

  • Stability: Stable under normal storage; decomposes on strong heating

  • Melting Point: Decomposes above 240°C

  1. Safety & Hazard Attributes

  • Hazard Class (GHS): Not classified as hazardous

  • Toxicity: Low toxicity; may cause mild irritation to eyes and skin on contact

  • Exposure Limits: Not established

  1. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry place away from moisture and incompatible substances

  • Container Type: Sealed polyethylene bags or drums

  • Shelf Life: 2–3 years if stored properly

  • Handling Precautions: Avoid dust generation; use PPE to prevent eye and respiratory irritation

  1. Regulatory & Compliance Attributes

  • Approved for use in food, pharmaceuticals, cosmetics, and industrial applications by FDA, EFSA, and other regulatory bodies

  • Complies with REACH and other environmental and safety regulations

  1. Environmental & Health Impact

  • Biodegradability: Slowly biodegradable; persists under some environmental conditions

  • Ecotoxicity: Low to moderate; avoid release in high concentrations to aquatic environments

  • Bioaccumulation: Not expected

Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required:

  • Dust mask or respirator (for powder handling)

  • Safety goggles

  • Gloves (nitrile or latex)

  • Protective clothing or lab coat

Handling Guidelines:

  • Handle in well-ventilated areas

  • Avoid inhalation of dust and eye contact

  • Use dust extraction systems when handling bulk powder

  • Prevent spills and clean promptly

Storage Measures:

  • Keep containers tightly closed

  • Store away from acids and strong oxidizers

  • Avoid exposure to moisture and humidity

Hygiene Practices:

  • Wash hands thoroughly after handling

  • Do not eat, drink, or smoke in the work area

  • Use clean equipment and avoid cross-contamination

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if irritation persists

  • Skin Contact: Wash with soap and water; seek medical advice if irritation occurs

  • Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek medical advice

  • Ingestion: Rinse mouth with water; seek medical advice if large amounts ingested

Firefighting Measures

  • Fire Hazards: Non-flammable

  • Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide

  • Special Precautions: None specific; use standard protective equipment

Decomposition Products: May emit toxic fumes of nitrogen oxides and sodium oxides upon decomposition