EDTA Disodium Salt

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EDTA Disodium Salt (Ethylenediaminetetraacetic acid disodium salt) is a widely used chelating agent that binds metal ions to form stable complexes. It effectively sequesters divalent and trivalent metal ions such as calcium, magnesium, iron, and heavy metals, preventing their participation in unwanted chemical reactions. This property makes it essential in a wide range of industrial, pharmaceutical, cosmetic, agricultural, and water treatment applications. The disodium salt form offers excellent water solubility and is often used in neutral to slightly alkaline systems.

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Categories: Chelating Agents, Excipients, Preservatives, Preservatives(food), Scale Inhibitors( water) Tags: Disodium EDTA, EDTA Disodium Salt, Fertilizer Additive, Hard Water Softener, Preservative Enhancer, Scale Inhibitor, Shampoo/Cream Stabilizer

Description

EDTA Disodium Salt Uses

Table of Contents

Primary Uses

Water Treatment & Industrial Cleaning

Used extensively to chelate metal ions in boiler feedwater and cooling water systems to prevent scale formation and corrosion.
Acts as a metal ion scavenger in detergents and industrial cleaners to improve cleaning efficiency.
Prevents discoloration and deposits caused by metal ions in pulp and paper processing.

Pharmaceuticals & Medicine

Employed as a chelating agent to reduce metal-induced oxidative degradation in formulations.
Used in chelation therapy to treat heavy metal poisoning by binding and facilitating metal excretion.
Stabilizes active ingredients in injectable and topical drug formulations.

Cosmetics & Personal Care

Added to shampoos, lotions, creams, and soaps to bind metal ions that cause product degradation and spoilage.
Improves foam stability and texture in cleansing products by softening water hardness.
Enhances product shelf life by preventing color changes and rancidity.

Food Industry

Used as a food additive (E385) to preserve color, flavor, and texture by binding metal ions that catalyze oxidation.
Commonly used in canned foods, beverages, and processed products to enhance stability.

Agriculture & Horticulture

Serves as a micronutrient chelator to improve bioavailability of trace metals like iron, zinc, and manganese in fertilizers and foliar sprays.
Prevents metal ion precipitation and enhances nutrient uptake in plants.

Secondary Uses

Analytical Chemistry

Used in complexometric titrations to determine metal ion concentrations.

Textile Industry

Functions as a stabilizer and metal ion scavenger to prevent color fading and fabric degradation.

Photography

Utilized in photographic developers to control metal ion interference.

PRODUCT KEY FEATURES

Basic Identification Attributes

Chemical Name (IUPAC): Disodium 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
Common/Trade Name: EDTA Disodium Salt
CAS Number: 139-33-3
HS Code: 2922.49.00
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Synonyms:
- Ethylenediaminetetraacetic acid disodium salt
- EDTA-2Na
- Disodium EDTA
- Versenate Sodium

Physical & Chemical Properties

Physical State: White crystalline powder or granules
Color & Odor: White; odorless
pH (1% aqueous solution): Approximately 4.5–5.5
Solubility: Freely soluble in water; insoluble in ethanol and non-polar solvents
Stability: Stable under normal storage; decomposes on strong heating
Melting Point: Decomposes above 240°C

Safety & Hazard Attributes

Hazard Class (GHS): Not classified as hazardous
Toxicity: Low toxicity; may cause mild irritation to eyes and skin on contact
Exposure Limits: Not established

Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place away from moisture and incompatible substances
Container Type: Sealed polyethylene bags or drums
Shelf Life: 2–3 years if stored properly
Handling Precautions: Avoid dust generation; use PPE to prevent eye and respiratory irritation

Regulatory & Compliance Attributes

Approved for use in food, pharmaceuticals, cosmetics, and industrial applications by FDA, EFSA, and other regulatory bodies
Complies with REACH and other environmental and safety regulations

Environmental & Health Impact

Biodegradability: Slowly biodegradable; persists under some environmental conditions
Ecotoxicity: Low to moderate; avoid release in high concentrations to aquatic environments
Bioaccumulation: Not expected

Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required:

Dust mask or respirator (for powder handling)
Safety goggles
Gloves (nitrile or latex)
Protective clothing or lab coat

Handling Guidelines:

Handle in well-ventilated areas
Avoid inhalation of dust and eye contact
Use dust extraction systems when handling bulk powder
Prevent spills and clean promptly

Storage Measures:

Keep containers tightly closed
Store away from acids and strong oxidizers
Avoid exposure to moisture and humidity

Hygiene Practices:

Wash hands thoroughly after handling
Do not eat, drink, or smoke in the work area
Use clean equipment and avoid cross-contamination

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if irritation persists
Skin Contact: Wash with soap and water; seek medical advice if irritation occurs
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek medical advice
Ingestion: Rinse mouth with water; seek medical advice if large amounts ingested