Preservatives(food)
Flavors
Acidulants
Sweeteners
Antioxidants
Colorants(food)
Nutraceutical Ingredients (food)
Nutrient Supplements
Emulsifiers
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Oils
Carrier Oills
Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fragrance (Cosmetics)
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Solvents(lab)
Chromatography Chemicals
Spectroscopy Reagents
microbiology-and-cell-culture-reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders
HPMC Vivapharm E50
HPMC Vivapharm is a high-quality, pharmaceutical-grade hydroxypropyl methylcellulose polymer widely used as an excipient and functional ingredient. It appears as a fine, white to off-white, odorless powder with excellent solubility in cold water and forms clear, viscous solutions. This cellulose ether derivative offers excellent film-forming, thickening, emulsifying, and controlled-release properties. Vivapharm E50 is prized in pharmaceutical, food, and cosmetic industries for its versatility, stability, and safety profile.
HPMC Vivapharm E50
Primary Uses
- Pharmaceutical Industry
- Used as a tablet binder and film former in oral solid dosage forms to improve tablet integrity and controlled drug release.
- Acts as a matrix former in sustained-release formulations, providing controlled dissolution profiles for active pharmaceutical ingredients.
- Functions as a disintegrant or swellable excipient to facilitate tablet disintegration where required.
- Utilized as a suspending agent and viscosity enhancer in liquid oral formulations and ophthalmic preparations.
- Serves as a protective coating agent for tablets and capsules to mask taste and improve stability.
- Food Industry
- Employed as a thickener, stabilizer, and emulsifier in sauces, dressings, bakery products, and dairy alternatives.
- Used as a gluten substitute or additive in gluten-free baked goods to improve texture and moisture retention.
- Enhances mouthfeel and shelf-life in low-fat and reduced-calorie food formulations.
- Cosmetics and Personal Care
- Functions as a thickening agent and film former in lotions, creams, shampoos, and conditioners.
- Provides stabilization in emulsions and suspensions, preventing ingredient separation.
- Used in hair gels and styling products for desired viscosity and texture.
- Industrial Applications
- Acts as a rheology modifier in paints, adhesives, and printing inks to control flow properties.
- Used in construction materials such as tile adhesives and cementitious coatings to improve workability and water retention.
Secondary Uses
- Biomedical Research
- Used as a hydrogel base for drug delivery and tissue engineering studies.
- Employed in cell culture media as a viscosity modifier.
- Agriculture
- Utilized as a carrier or binder in pesticide formulations to improve adhesion and controlled release.
- Packaging
- Incorporated into biodegradable films and edible coatings for food packaging applications.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Hydroxypropyl methylcellulose
- Common/Trade Name: HPMC Vivapharm E50
- CAS Number: 9004-65-3
- HS Code: 3912.90.00
- Molecular Formula: C56H108O30 (approximate polymer unit)
- Synonyms: Hypromellose; Methylhydroxypropyl cellulose; Methocel E50
2. Physical & Chemical Properties
- Physical State: Fine powder
- Color & Odor: White to off-white; odorless
- Viscosity (2% aqueous solution): ~50 mPa·s at 20°C
- Solubility: Soluble in cold water, insoluble in hot water and organic solvents
- pH (1% solution): Neutral to slightly alkaline (6.5–8.5)
- Thermal Stability: Stable up to ~200°C
- Film-Forming Ability: Excellent, clear films upon drying
3. Safety & Hazard Attributes
- GHS Classification: Non-hazardous; Generally Recognized As Safe (GRAS)
- Toxicity: Non-toxic and non-irritant at typical use levels
- Exposure Limits: No specific occupational exposure limits
4. Storage & Handling Attributes
- Container Type: Sealed polyethylene bags or drums with moisture barrier
- Storage Conditions: Store in cool, dry place away from moisture and direct sunlight
- Shelf Life: Up to 36 months if stored properly
- Handling Notes: Avoid dust generation; use dust masks in bulk handling
5. Regulatory & Compliance Attributes
- Approved for pharmaceutical use by USP, EP, JP
- Food additive status approved by FDA (E464) and EFSA
- Complies with REACH and other global chemical regulations
6. Environmental & Health Impact
- Biodegradability: Biodegradable under aerobic conditions
- Ecotoxicity: Low environmental toxicity
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified
Safety Handling Precautions
- PPE Required: Dust mask, gloves, and safety goggles recommended during powder handling
- Handling Guidelines: Use in well-ventilated areas; avoid dust accumulation
- Hygiene Practices: Wash hands after handling; avoid inhalation of dust
First Aid Measures
- Inhalation: Move to fresh air if respiratory irritation occurs
- Skin Contact: Wash with soap and water if irritation develops
- Eye Contact: Rinse thoroughly with water for 15 minutes; seek medical advice if irritation persists
- Ingestion: Generally regarded as safe; seek medical advice if excessive ingestion occurs
Firefighting Measures
- Fire Hazards: Non-flammable, but may burn under extreme heat
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂
- Special Precautions: Avoid inhalation of smoke from burning material
- Combustion Products: Carbon oxides and other organic compounds
Related products
Cellulose Acetate Phthalate (CAP)
Cellulose Acetate Phthalate (CAP) is a cellulose derivative obtained by esterification of cellulose with acetic acid and phthalic anhydride. It appears as a white to off-white, free-flowing powder that is insoluble in water but soluble in alkaline solutions and certain organic solvents. CAP is primarily used as an enteric coating agent in pharmaceutical formulations, providing resistance to acidic gastric fluids and enabling targeted release of drugs in the intestines. Due to its film-forming, pH-sensitive solubility, and protective properties, CAP is also applied in food, cosmetics, and specialty industrial uses.
Cetyl Alcohol Flakes
Cetyl Alcohol Flakes is a high-purity fatty alcohol derived mainly from natural sources such as palm oil and coconut oil. Presented as white to off-white waxy flakes, this product contains at least 98% pure cetyl alcohol, ensuring consistent performance and quality. It is valued for its excellent emollient, thickening, and emulsifying properties and is widely used in personal care, pharmaceutical, and industrial formulations. The flake form facilitates easy handling, melting, and dosing in manufacturing processes. Cetyl Alcohol 98% Flakes contributes to the texture, stability, and moisturizing properties of various formulations, providing a non-greasy, smooth finish.
Dextrose Anhydrous BP Injectable
Dextrose Anhydrous BP Injectable is a sterile, highly purified crystalline form of glucose that serves as a critical energy source in intravenous therapy. It is widely used in parenteral nutrition, rehydration, and hypoglycemia management. The anhydrous form contains no water, allowing precise control of concentration in injectable solutions. Meeting British Pharmacopoeia (BP) standards, it ensures pharmaceutical-grade purity and sterility, suitable for direct injection or as a component in compounded IV fluids. It provides readily available carbohydrates metabolized to supply energy, regulate osmolarity, and maintain fluid-electrolyte balance in clinical care.
Dextrose Monohydrate
Dextrose Monohydrate is a crystalline form of glucose containing one molecule of water (monohydrate). It is a primary carbohydrate source widely used in pharmaceutical, food, and clinical nutrition applications. It provides readily available energy, serves as a sweetening agent, and acts as an osmotic agent in formulations. Dextrose Monohydrate meets pharmacopoeial standards (such as BP, USP) ensuring high purity, consistency, and safety for use in medical and food-grade products. Its solubility and stable crystalline form make it suitable for intravenous fluids, oral rehydration solutions, and food industry applications.
Lactose Monohydrate 200 Mesh
Lactose Monohydrate 200 Mesh is a fine, white, crystalline powder derived from milk sugar with a particle size of 200 mesh, indicating very fine granules. It is widely used in pharmaceutical, food, and confectionery industries as a filler, binder, and stabilizer. Lactose Monohydrate is valued for its excellent compressibility, low hygroscopicity, and compatibility with many active pharmaceutical ingredients (APIs). The monohydrate form contains one molecule of water, enhancing its stability and flow properties.
Magnesium Stearate BP
Magnesium Stearate BP is a fine, white, hydrophobic powder composed of the magnesium salt of stearic acid. It is widely used in the pharmaceutical industry as a lubricant and anti-adherent in tablet and capsule manufacturing. Due to its excellent flow-enhancing properties, Magnesium Stearate BP improves powder flowability and prevents ingredients from sticking to equipment during processing. It is also used in cosmetics, food, and various industrial applications for its emulsifying and stabilizing properties.
Potassium Metabisulphite Food Grade
Potassium Metabisulphite Food Grade is a white crystalline powder with strong antioxidant and preservative properties. It is widely used in the food and beverage industry as a disinfectant, antioxidant, and preservative to prevent spoilage and microbial growth. It also acts as a bleaching agent and sulfur dioxide (SO₂) source. This compound is critical in winemaking, brewing, and food processing to maintain product quality and extend shelf life.
Sodium Starch Glycolate
Sodium Starch Glycolate (SSG) is a white to off-white, odorless, tasteless powder derived from potato or maize starch and chemically modified with carboxymethylation and cross-linking. It has the chemical formula (C₆H₁₀O₅)nNa and is widely used in solid dosage pharmaceutical formulations as a superdisintegrant. This 25kg grade is supplied in high-purity pharmaceutical and food-grade quality, offering excellent swelling capacity and rapid disintegration properties even at low concentrations.
