Isopropyl Myristate

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Isopropyl Myristate is a clear, colorless, and oily liquid ester formed by the reaction of isopropyl alcohol and myristic acid. It has a mild, pleasant odor and excellent spreading properties. IPM is widely used in cosmetics, pharmaceuticals, and industrial applications as an emollient, solvent, and penetration enhancer due to its ability to improve texture and absorption of topical formulations.

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Categories: Emollients, Excipients, Fragrances and Essential Oils, Plasticizers Tags: Cosmetic formulations, Emollient & Solvent, Industrial Lubricants, Ink Additive, IPM Ester, Isopropyl Myristate (IPM), Massage Oils, Plasticizers

Description

Table of Contents

Isopropyl Myristate (IPM)

Primary Uses

Cosmetic and Personal Care Industry

Used as an emollient and moisturizer in creams, lotions, sunscreens, deodorants, and makeup products for smooth, non-greasy skin feel.
Functions as a penetration enhancer facilitating deeper delivery of active ingredients through the skin.
Acts as a solvent for fragrances, oils, and other cosmetic ingredients improving formulation stability and texture.

Pharmaceutical Industry

Utilized in topical creams, ointments, and gels to improve absorption of drugs through the skin.
Used as a vehicle for transdermal drug delivery systems.

Fragrance and Perfume Industry

Serves as a solvent and fixative to improve scent dispersion and longevity in perfumes and colognes.

Industrial Applications

Applied as a lubricant and anti-static agent in textile, plastics, and rubber industries.
Used in formulations of insect repellents and pesticide carriers.

Secondary Uses

Food Industry

Occasionally used as a flavor carrier or additive in specific food-grade applications (subject to regulatory approval).

Hair Care Products

Added to shampoos, conditioners, and styling products to enhance smoothness and reduce greasy residue.

Cleaning and Polishing Products

Used in specialized cleaning formulations and polishes for its lubricating and spreading properties.

Veterinary Applications

Employed in topical formulations for animals as a skin conditioner and drug delivery enhancer.

KEY ATTRIBUTES

Basic Identification Attributes

Chemical Name (IUPAC): Propan-2-yl tetradecanoate
Common/Trade Name: Isopropyl Myristate; IPM
CAS Number: 110-27-0
HS Code: 2915.70.00
Synonyms: Isopropyl tetradecanoate; IPM

Physical & Chemical Properties

Physical State: Clear oily liquid
Color & Odor: Colorless; mild, pleasant odor
Boiling Point: 280–285 °C
Melting Point: −9 °C
Density: 0.86 g/cm³ (approx.)
Solubility: Insoluble in water; soluble in most organic solvents
Flash Point: 118 °C

Safety & Hazard Attributes

GHS Classification:

Not classified as hazardous under typical use
May cause mild skin or eye irritation in sensitive individuals

Toxicity:

Low toxicity; generally regarded as safe in cosmetic and pharmaceutical use

Exposure Limits:

No established occupational exposure limits

Storage & Handling Attributes

Storage Conditions:

Store in a cool, dry, well-ventilated area away from strong oxidizers

Container Type:

Stored in tightly sealed plastic or metal containers

Shelf Life:

Stable for 2–3 years if stored properly

Handling Precautions:

Avoid prolonged skin contact and inhalation of vapors
Use appropriate PPE when handling in bulk

Regulatory & Compliance Attributes

Approved for use in cosmetics and pharmaceuticals by FDA, EMA, and other regulatory bodies
Complies with REACH and other chemical safety standards
Must be labeled according to cosmetic ingredient regulations

Environmental & Health Impact

Biodegradability: Readily biodegradable
Ecotoxicity: Low toxicity to aquatic organisms
Bioaccumulation: Not expected to bioaccumulate
Carcinogenicity/Mutagenicity: Not classified as carcinogenic

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required:

Gloves and goggles recommended during handling of bulk material

Handling Guidelines:

Avoid direct skin and eye contact
Ensure adequate ventilation during use

Storage Measures:

Keep containers tightly closed and away from heat sources

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if symptoms develop
Skin Contact: Wash thoroughly with soap and water; if irritation develops, get medical advice
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek medical attention if irritation persists
Ingestion: Rinse mouth and seek medical advice if significant amounts ingested

Firefighting Measures

Fire Hazards: Combustible liquid; may burn but with low flame spread
Extinguishing Media: Use foam, dry chemical, or CO₂ extinguishers
Special Precautions: Wear full protective gear and self-contained breathing apparatus if involved in fire
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, and other toxic fumeS