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Lidocaine HCL BP
Lidocaine HCL BP is a white crystalline powder or granules that are highly soluble in water. It is a local anesthetic and antiarrhythmic agent widely used in medical and dental fields. Lidocaine HCL BP acts by blocking nerve signal transmission, providing rapid and effective numbing of targeted areas. It conforms to British Pharmacopoeia (BP) standards, ensuring pharmaceutical-grade purity and consistency. It is commonly formulated into injections, topical gels, creams, and patches for pain relief and arrhythmia treatment.
Lidocaine HCL BP
Primary UsesÂ
- Medical and Dental Anesthesia
- Local Anesthetic: Used for numbing skin, mucous membranes, and deeper tissues during minor surgical procedures, dental work, and diagnostic tests.
- Regional Anesthesia: Employed in nerve blocks, epidurals, and spinal anesthesia for surgeries and pain management.
- Topical Anesthesia: Applied in creams, gels, or sprays for superficial pain relief such as sunburn, insect bites, and minor skin irritations.
- Cardiology
- Antiarrhythmic Agent: Administered intravenously to treat ventricular arrhythmias, including ventricular tachycardia and ventricular fibrillation during acute cardiac events.
- Pharmaceutical Formulations
- Component in compounded topical analgesics and patches designed for localized pain relief.
- Used in combination with other agents to enhance efficacy in multi-ingredient preparations.
Secondary Uses
- Veterinary Medicine
- Used as a local anesthetic in animals for minor surgical and dental procedures.
- Cosmetic Procedures
- Utilized to reduce pain during cosmetic interventions such as laser treatments, tattooing, and dermal filler injections.
- Research Applications
- Used experimentally to study nerve function and local anesthetic pharmacodynamics.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride
- Common/Trade Name: Lidocaine HCL BP; Lidocaine Hydrochloride
- CAS Number: 73-78-9
- HS Code: 2941.00.00
- Synonyms: Lignocaine Hydrochloride; Xylocaine Hydrochloride; Lidocaine HCl
2. Physical & Chemical Properties
- Physical State: Crystalline powder
- Color & Odor: White to off-white; odorless to faint aromatic odor
- Solubility: Freely soluble in water; slightly soluble in alcohol and chloroform
- Melting Point: 68–72 °C
3. Safety & Hazard Attributes
- GHS Classification: Harmful if swallowed; causes skin and eye irritation; may cause respiratory irritation
- Toxicity: Moderate toxicity; overdose can cause CNS and cardiovascular effects
- Exposure Limits: No specific occupational limits, but handle with care
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, protected from light and moisture
- Container Type: Sealed pharmaceutical-grade containers
- Shelf Life: Typically 2–3 years under proper storage
- Handling Precautions: Avoid inhalation and direct contact; use protective equipment
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Approved for human medical use in many countries
- Labeling must comply with pharmaceutical regulatory guidelines
6. Environmental & Health Impact
- Biodegradability: Not readily biodegradable
- Ecotoxicity: Avoid environmental release; potentially harmful to aquatic life
- Bioaccumulation: Not significant
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic
Safety Handling Precautions
- PPE Required: Gloves, safety goggles, and lab coat recommended
- Handling Guidelines: Use in well-ventilated areas; avoid dust and inhalation
- Storage Measures: Keep containers tightly closed and away from incompatible substances
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms develop
- Skin Contact: Wash with soap and water; seek medical advice if irritation occurs
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical help if irritation persists
- Ingestion: Do not induce vomiting; seek immediate medical attention
Firefighting Measures
- Fire Hazards: Combustible; emits toxic fumes upon burning
- Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
- Special Precautions: Wear full protective gear and self-contained breathing apparatus if involved in fire
- Hazardous Combustion Products: Carbon monoxide, nitrogen oxides, and other toxic gases
Related products
Diclofenac Sodium BP
Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) widely used for its potent analgesic, anti-inflammatory, and antipyretic properties. It is the sodium salt form of diclofenac, providing enhanced solubility and rapid absorption. Diclofenac Sodium BP (British Pharmacopoeia standard) ensures pharmaceutical-grade purity and compliance with stringent quality standards. It is commonly formulated in oral tablets, topical gels, injections, and ophthalmic preparations.
Dicyclomine Hydrochloride
Dicyclomine Hydrochloride is an anticholinergic and antispasmodic agent used primarily to relieve smooth muscle spasms in the gastrointestinal tract. It works by blocking muscarinic receptors, thereby reducing muscle contractions and spasms, which helps alleviate symptoms of irritable bowel syndrome (IBS) and other functional bowel disorders. It is commonly available in oral tablets, capsules, and injectable formulations.
Diphenhydramine HCL BP
Diphenhydramine HCL BP is a first-generation antihistamine with potent anticholinergic, sedative, and antiemetic properties. It is commonly used to relieve symptoms associated with allergies, hay fever, the common cold, and motion sickness. Diphenhydramine HCL is a white crystalline powder, highly soluble in water, making it suitable for oral, topical, and injectable pharmaceutical formulations. Due to its ability to cross the blood-brain barrier, it causes sedation and is often used as a sleep aid and for managing Parkinson’s disease symptoms.
Ichthammol BP98
Ichthammol BP98, also known as ammonium bituminosulfonate, is a dark brown to black, viscous, sulfur-rich, semi-solid substance derived from the distillation of shale or bituminous rocks. It has a characteristic tar-like odor and is highly valued in pharmaceutical and dermatological applications for its anti-inflammatory, antiseptic, antipruritic (anti-itch), and keratolytic properties. Ichthammol penetrates deeply into the skin and soft tissues, helping to alleviate inflammation and promote healing. It is widely used in topical preparations for treating skin conditions such as eczema, psoriasis, boils, abscesses, and other dermatological infections.
Levamisole Hcl BP2000
Levamisole Hcl BP2000 is a white to off-white crystalline powder, soluble in water, with anthelmintic and immunomodulatory properties. It is primarily used as a veterinary antiparasitic agent effective against gastrointestinal nematodes in livestock. Levamisole HCL BP2000 conforms to British Pharmacopoeia standards, ensuring high purity and quality for pharmaceutical and veterinary formulations. Beyond veterinary uses, it is also researched for immunostimulant properties in medical applications.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole BP
Metronidazole BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Norfloxacin
Norfloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic used primarily to treat bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Norfloxacin is effective against various Gram-negative and some Gram-positive bacteria and is commonly used in urinary tract infections, prostatitis, and gastroenteritis.
