Oxyclozanide Vet BP

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Oxyclozanide Vet BP is a veterinary anthelmintic effective mainly against liver fluke (Fasciola hepatica) and some intestinal flukes in ruminants such as cattle, sheep, and goats. It works by interfering with the parasite’s energy metabolism, leading to parasite death and improving animal health and productivity.

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Category: Active Pharmaceutical Ingredients (APIs) Tags: Animal Health Care, Anti-Parasitic Drug, Oxyclozanide, Oxyclozanide Vet BP, Pharmaceutical Manufacturing, Veterinary Medicine

Description

Table of Contents

Oxyclozanide Vet BP

Primary Uses

Liver Fluke Control in Ruminants
- Treats acute and chronic infections caused by Fasciola hepatica.
- Reduces liver damage and associated clinical symptoms (anemia, weight loss).
- Improves productivity (milk yield, weight gain) in infected animals.
Control of Intestinal Trematodes
- Effective against Paramphistomum spp. and other rumen flukes.
- Helps maintain gastrointestinal health and digestion efficiency.
Veterinary Anthelmintic Therapy
- Used as a stand-alone treatment for fluke infections in cattle and sheep.
- Administered orally in doses according to veterinary prescription.

Secondary Uses

Preventive Deworming Programs
- Used strategically during high-risk seasons to prevent heavy fluke infestations.
- Reduces pasture contamination by minimizing parasite egg shedding.
Combination Therapy
- Occasionally combined with other antiparasitic agents (e.g., albendazole) for broader parasite spectrum coverage.
Goat and Other Ruminant Use
- Off-label use under veterinary supervision for fluke treatment in goats and other ruminants.
Improvement of Meat and Dairy Quality
- By controlling parasitic infections, it helps improve overall animal health and product quality.
Use in Mixed-Parasite Infections
- Helpful in farms where liver fluke infections occur alongside other gastrointestinal parasites, as part of integrated parasite management.
Research and Diagnostic Uses
- Used in veterinary research to study fluke resistance and pharmacodynamics.

KEY PRODUCT FEATURES

1. Basic Identification Attributes

Chemical Name (IUPAC): 2-[(4-Chlorophenyl)carbamoyl]-3,5-dichlorobenzoic acid
Common/Trade Name: Oxyclozanide Vet BP
CAS Number: 2272-92-8
HS Code: 2933.79.90
Synonyms: Oxyclozanide; Salicylanilide derivative

2. Physical & Chemical Properties

Physical State: White to off-white crystalline powder
Color & Odor: Odorless to mild characteristic odor
Solubility: Slightly soluble in water; soluble in organic solvents such as ethanol and acetone
Melting Point: Approximately 195–200 °C

3. Safety & Hazard Attributes

GHS Classification: Not classified as hazardous; standard veterinary chemical precautions apply
Toxicity: Low toxicity to mammals when used as directed
Exposure Limits: Use protective equipment to avoid dust inhalation

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry, well-ventilated area away from direct sunlight
Container Type: Supplied in sealed plastic or paper bags with liners
Shelf Life: Typically 2 years if stored properly
Handling Precautions: Avoid inhalation and prolonged skin contact; use gloves and dust mask if necessary

5. Regulatory & Compliance Attributes

Complies with BP (British Pharmacopoeia) veterinary standards
Approved for veterinary use under relevant national regulations

6. Environmental & Health Impact

Biodegradability: Moderate biodegradability
Ecotoxicity: Avoid release into the environment to prevent aquatic toxicity
Bioaccumulation: Not expected to bioaccumulate
Carcinogenicity/Mutagenicity: No evidence of carcinogenic or mutagenic effects

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required: Gloves, dust mask, and safety goggles recommended during handling
Handling Guidelines: Use in well-ventilated areas; avoid inhaling dust and contact with skin and eyes
Storage Measures: Keep containers tightly closed and away from incompatible substances

First Aid Measures

Inhalation: Move affected person to fresh air; seek medical advice if symptoms develop
Skin Contact: Wash skin thoroughly with soap and water; seek medical attention if irritation occurs
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; consult a doctor if irritation persists
Ingestion: Do not induce vomiting; seek medical attention promptly

Firefighting Measures

Fire Hazards: Non-flammable
Extinguishing Media: Use water spray, foam, dry chemical, or CO₂ extinguishers as appropriate
Special Precautions: Use standard protective firefighting gear
Hazardous Combustion Products: May produce toxic fumes under fire conditions