Pullulan

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Pullulan is a natural polysaccharide polymer produced by the fermentation of starch by the fungus Aureobasidium pullulans. It is a water-soluble, tasteless, and odorless biopolymer widely used in the food, pharmaceutical, and cosmetic industries due to its excellent film-forming, adhesive, and oxygen barrier properties. Pullulan is biodegradable, non-toxic, and approved for use in various applications requiring edible and biodegradable films.

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Categories: Excipients, Thickeners Tags: Food & Beverage Industry, Natural Polysaccharide, Pharmaceuticals, Pullulan, White powder or granules

Description

Table of Contents

Pullulan

Primary Uses

Food Industry

Used as an edible film and coating agent to improve shelf life and freshness of food products.
Acts as a thickener, stabilizer, and binder in confectionery, bakery, and beverage formulations.
Utilized in the manufacture of breath freshener strips and oral dissolvable films.

Pharmaceutical Industry

Employed in film coating of tablets and capsules for controlled release and improved stability.
Used as a carrier in oral thin films and drug delivery systems.

Cosmetics

Incorporated in skincare products as a film-former and moisturizer enhancer.

Secondary Uses

Packaging Industry

Utilized in biodegradable packaging films as an eco-friendly alternative to synthetic plastics.

Agriculture

Applied in seed coatings and controlled-release formulations for agrochemicals.

Biomedical Applications

Investigated for wound dressings, tissue engineering scaffolds, and other medical uses due to its biocompatibility.

KEY PRODUCT FEATURES

1. Basic Identification Attributes

Chemical Name (IUPAC): (1→4)-α-D-Glucan
Common/Trade Name: Pullulan
CAS Number: 9057-02-7
HS Code: 3913.90
Synonyms: Polysaccharide polymer; edible film-forming agent

2. Physical & Chemical Properties

Physical State: Powder or flakes
Color & Odor: White to off-white; odorless
Solubility: Soluble in water; insoluble in organic solvents
Density: Approximately 1.3 g/cm³ (dry powder)
Viscosity: Depends on molecular weight and concentration

3. Safety & Hazard Attributes

GHS Classification: Generally non-hazardous
Toxicity: Low toxicity; biocompatible and non-irritant
Exposure Limits: Not established; handle as per good industrial hygiene

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place away from moisture and contaminants
Container Type: Sealed bags, drums, or containers
Shelf Life: Typically 12–24 months depending on storage conditions
Handling Precautions: Avoid dust formation; use protective masks and gloves if dusty

5. Regulatory & Compliance Attributes

Complies with food-grade standards such as FDA GRAS status and EFSA approval
Meets pharmaceutical excipient regulatory requirements

6. Environmental & Health Impact

Biodegradability: Biodegradable under natural conditions
Ecotoxicity: Low environmental impact
Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required: Gloves, dust mask, and eye protection recommended during handling
Handling Guidelines: Use in well-ventilated areas; avoid inhaling dust

First Aid Measures

Inhalation: Move to fresh air; seek medical advice if irritation occurs
Skin Contact: Wash with soap and water if irritation develops
Eye Contact: Rinse with water for 15 minutes; seek medical attention if irritation persists
Ingestion: Generally safe; seek medical help if discomfort occurs

Firefighting Measures

Fire Hazards: Combustible under fire conditions
Extinguishing Media: Water spray, foam, dry chemical, or CO₂
Special Precautions: Use protective equipment and avoid inhaling combustion fumes
Hazardous Combustion Products: Carbon oxides and other organic combustion products