Pullulan

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Pullulan is a natural polysaccharide polymer produced by the fermentation of starch by the fungus Aureobasidium pullulans. It is a water-soluble, tasteless, and odorless biopolymer widely used in the food, pharmaceutical, and cosmetic industries due to its excellent film-forming, adhesive, and oxygen barrier properties. Pullulan is biodegradable, non-toxic, and approved for use in various applications requiring edible and biodegradable films.

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Categories: Emulsifiers, Excipients, FOOD AND BEVERAGE CHEMICALS, PHARMACEUTICAL CHEMICALS Tags: Food & Beverage Industry, Natural Polysaccharide, Pharmaceuticals, Pullulan, White powder or granules

Description

Primary Uses

Food Industry
- Used as an edible film and coating agent to improve shelf life and freshness of food products.
- Acts as a thickener, stabilizer, and binder in confectionery, bakery, and beverage formulations.
- Utilized in the manufacture of breath freshener strips and oral dissolvable films.
Pharmaceutical Industry
- Employed in film coating of tablets and capsules for controlled release and improved stability.
- Used as a carrier in oral thin films and drug delivery systems.
Cosmetics
- Incorporated in skincare products as a film-former and moisturizer enhancer.

Secondary Uses

Packaging Industry
- Utilized in biodegradable packaging films as an eco-friendly alternative to synthetic plastics.
Agriculture
- Applied in seed coatings and controlled-release formulations for agrochemicals.
Biomedical Applications

Investigated for wound dressings, tissue engineering scaffolds, and other medical uses due to its biocompatibility.

PRODUCT KEY FEATURES

Basic Identification Attributes

Chemical Name (IUPAC): (1→4)-α-D-Glucan
Common/Trade Name: Pullulan
CAS Number: 9057-02-7
HS Code: 3913.90
Synonyms: Polysaccharide polymer; edible film-forming agent

Physical & Chemical Properties

Physical State: Powder or flakes
Color & Odor: White to off-white; odorless
Solubility: Soluble in water; insoluble in organic solvents
Density: Approximately 1.3 g/cm³ (dry powder)
Viscosity: Depends on molecular weight and concentration

Safety & Hazard Attributes

GHS Classification: Generally non-hazardous
Toxicity: Low toxicity; biocompatible and non-irritant
Exposure Limits: Not established; handle as per good industrial hygiene

Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place away from moisture and contaminants
Container Type: Sealed bags, drums, or containers
Shelf Life: Typically 12–24 months depending on storage conditions
Handling Precautions: Avoid dust formation; use protective masks and gloves if dusty

Regulatory & Compliance Attributes

Complies with food-grade standards such as FDA GRAS status and EFSA approval
Meets pharmaceutical excipient regulatory requirements

Environmental & Health Impact

Biodegradability: Biodegradable under natural conditions
Ecotoxicity: Low environmental impact
Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

PPE Required: Gloves, dust mask, and eye protection recommended during handling
Handling Guidelines: Use in well-ventilated areas; avoid inhaling dust

First Aid Measures

Inhalation: Move to fresh air; seek medical advice if irritation occurs
Skin Contact: Wash with soap and water if irritation develops
Eye Contact: Rinse with water for 15 minutes; seek medical attention if irritation persists
Ingestion: Generally safe; seek medical help if discomfort occurs

Firefighting Measures

Fire Hazards: Combustible under fire conditions
Extinguishing Media: Water spray, foam, dry chemical, or CO₂
Special Precautions: Use protective equipment and avoid inhaling combustion fumes
Hazardous Combustion Products: Carbon oxides and other organic combustion products