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Salbutamol Sulphate BP
Salbutamol Sulphate BP is a white to off-white crystalline powder widely used as a bronchodilator in the treatment of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. It works by relaxing the muscles in the airways, improving airflow and easing breathing. The British Pharmacopoeia (BP) grade ensures high purity and quality suitable for pharmaceutical formulations such as inhalers, tablets, and syrups.
Salbutamol Sulphate BP
Primary Uses
- Pharmaceuticals
- Used in oral, inhalation, and injectable formulations to relieve bronchospasm in asthma and COPD patients.
- Administered as a short-acting beta-2 adrenergic receptor agonist for quick relief of respiratory symptoms.
- Included in combination therapies with corticosteroids or other bronchodilators for maintenance treatment.
- Veterinary Medicine
- Employed to treat respiratory distress and bronchoconstriction in animals.
Secondary UsesÂ
- Research & Development
- Used as a reference standard in analytical testing and formulation development of respiratory drugs.
- Pharmaceutical Manufacturing
- Utilized in formulation trials and bioequivalence studies of bronchodilator medications.
1. Basic Identification Attributes
- Chemical Name (IUPAC): (RS)-4-[2-(tert-Butylamino)-1-hydroxyethyl]benzene-1,2-diol sulfate (salt)
- Common/Trade Name: Salbutamol Sulphate BP
- CAS Number: 18559-94-9
- HS Code: 2933.39
- Synonyms: Albuterol sulfate, Ventolin sulfate
2. Physical & Chemical Properties
- Physical State: Crystalline powder
- Color & Odor: White to off-white; odorless
- Solubility: Soluble in water, slightly soluble in alcohol
- Melting Point: Approximately 220°C (decomposes)
- Stability: Stable under recommended storage conditions
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under normal handling; may cause irritation
- Toxicity: Low toxicity at therapeutic doses; overdose can cause side effects
- Exposure Limits: Follow pharmaceutical handling guidelines
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, protected from light and moisture
- Container Type: Supplied in sealed pharmaceutical-grade packaging
- Shelf Life: Typically 2–3 years under proper storage
- Handling Precautions: Use gloves and mask to avoid inhalation or skin contact
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards for purity and quality
- Approved by major regulatory agencies for pharmaceutical use
6. Environmental & Health Impact
- Biodegradability: Not readily biodegradable; handle waste according to regulations
- Ecotoxicity: Low environmental risk if disposed of properly
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves, mask, and eye protection recommended
- Handling Guidelines: Avoid inhalation and prolonged skin contact; use in well-ventilated areas
- Storage Measures: Keep containers tightly closed and stored in a dry environment away from light
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if breathing difficulties occur
- Skin Contact: Wash with soap and water; seek medical advice if irritation develops
- Eye Contact: Rinse thoroughly with water for 15 minutes; get medical attention if irritation persists
- Ingestion: Rinse mouth; seek medical help immediately
Firefighting Measures
- Fire Hazards: Not highly flammable but may decompose on heating to produce toxic fumes
- Extinguishing Media: Use water spray, foam, dry chemical, or COâ‚‚
- Special Precautions: Use protective clothing and self-contained breathing apparatus if necessary
- Hazardous Combustion Products: Carbon oxides, nitrogen oxides, sulfur oxides
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Lidocaine HCL BP
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