Silk Proteins

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Silk Proteins are hydrolyzed proteins derived from natural silk fibers, typically composed of fibroin and sericin. They are water-soluble, bioactive compounds known for their excellent film-forming, moisture-retaining, and conditioning properties. Silk proteins are widely used in cosmetics, personal care products, pharmaceuticals, and textiles due to their biocompatibility, smooth texture, and ability to penetrate and protect surfaces like skin, hair, and fabric.

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Categories: COSMETIC AND PERSONAL CARE CHEMICALS, Excipients, FOOD AND BEVERAGE CHEMICALS, Humectants, Nutraceutical Ingredients (food), PHARMACEUTICAL CHEMICALS Tags: Cosmetic Active Ingredient, Hydrolyzed Silk Protein, Natural Protein Extract, Silk Amino Acids, Silk Proteins

Description

Table of Contents

Silk Proteins

Primary Uses

Cosmetics & Personal Care

Used in shampoos, conditioners, and hair treatments for softness, shine, and improved manageability.
Included in skincare formulations (creams, serums, lotions) to enhance hydration and skin smoothness.
Forms a breathable, protective film on skin and hair to retain moisture.
Applied in anti-aging products due to its amino acid content and skin-rejuvenating properties.
Used in soaps and body washes for a silky lather and reduced dryness.

Textile Industry

Acts as a conditioning and softening agent in fabric finishing treatments.
Enhances the strength and smoothness of natural and synthetic textiles.
Applied in luxury fabrics and garments to improve luster and hand feel.

Pharmaceuticals

Used as a bio-compatible film former in wound dressings and topical formulations.
Acts as a carrier for active pharmaceutical ingredients in controlled-release drug systems.
Included in ocular preparations and hydrogels for enhanced biocompatibility.

Hair Care Products

Strengthens hair shafts and reduces breakage by binding to keratin.
Used in hair dyes and bleaches to protect hair from chemical damage.

Secondary Uses

Biomedical Applications

Investigated for use in tissue engineering, scaffolds, and regenerative medicine due to its structural properties.
Used in biodegradable microcapsules for drug delivery.

Nutraceuticals & Supplements

Hydrolyzed silk peptides are marketed as dietary supplements for hair, skin, and nail health.

Coatings & Films

Used in biodegradable films and coatings for packaging sensitive materials.
Acts as a protective coating for food and pharmaceutical tablets.

Printing & Paper

Added to specialty papers to enhance surface texture and durability.
Used in art paper for premium finishes and moisture resistance.

PRODUCT KEY FEATURES

Basic Identification Attributes

Chemical Name (IUPAC): Hydrolyzed fibroin and sericin proteins
Common/Trade Name: Silk Proteins
CAS Number: 96690-41-4 (for hydrolyzed silk protein)
HS Code: 3504.00.00
Synonyms: Hydrolyzed silk protein, silk amino acids, silk peptides

Physical & Chemical Properties

Physical State: Liquid or powder (depending on form)
Color & Odor: Pale yellow to amber (liquid), off-white (powder); faint characteristic odor
Solubility: Soluble in water
pH: Typically 4.5 – 7.5 (aqueous solution)
Molecular Weight: Varies; silk peptides usually <10,000 Da
Stability: Stable under normal storage conditions

Safety & Hazard Attributes

GHS Classification: Not classified as hazardous
Toxicity: Non-toxic and non-irritant at recommended concentrations
Exposure Limits: No specific occupational exposure limits
Allergenic Potential: Low, but patch testing is advised for sensitive individuals

Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place, protected from light and moisture
Container Type: HDPE drums, fiber drums, or sealed foil bags (for powder)
Shelf Life: 12–24 months if stored properly
Handling Precautions: Use clean utensils to avoid contamination; avoid excessive heat

Regulatory & Compliance Attributes

Complies with cosmetic regulations (e.g., EU Cosmetic Regulation, FDA Cosmetic Ingredient Review)
Approved for use in personal care products under INCI: Hydrolyzed Silk
Meets relevant purity standards for pharmaceutical excipients where applicable
Produced in GMP-compliant or ISO-certified facilities (varies by supplier)

Environmental & Health Impact

Biodegradability: Readily biodegradable
Ecotoxicity: Low; safe for aquatic and terrestrial environments at typical use levels
Bioaccumulation: Not expected

Environmental Impact: Minimal when used in cosmetics or textiles; safe for rinse-off applications

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required: Gloves and goggles recommended for bulk handling
Handling Guidelines: Avoid inhalation of fine powders; ensure clean tools to prevent contamination
Storage Measures: Keep containers tightly closed and stored in a dry environment

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if symptoms persist
Skin Contact: Wash with soap and water; unlikely to cause irritation
Eye Contact: Rinse with water; seek medical attention if irritation continues
Ingestion: Rinse mouth; not expected to be harmful in small quantities

Firefighting Measures

Fire Hazards: Non-flammable
Extinguishing Media: Water spray, CO₂, dry chemical, or foam
Special Precautions: Use protective equipment if fire involves packaging or other combustible materials
Hazardous Combustion Products: Carbon oxides, nitrogen oxides