Acidulants
Antioxidants
Nutraceutical Ingredients (food)
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Fragrances and Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Chromatography Chemicals
Spectroscopy Reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Fresh Herbs
Ground Spices
Whole Spices
Spice Blends
Dried Herbs
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders
Simethicone 100% USP 28
Whatsapp Order
Simethicone 100% USP 28 is a silicon-based surfactant used primarily as an anti-foaming and anti-gas agent in pharmaceutical and food industries. It works by reducing the surface tension of gas bubbles, causing them to coalesce and be expelled more easily from the digestive tract. This non-toxic, inert compound is widely used in formulations to relieve bloating, discomfort, and flatulence caused by excess gas. The “USP 28” grade signifies compliance with the United States Pharmacopeia standards, ensuring high purity and quality for medical and food applications.
Description
Uses
Primary Uses
Pharmaceutical Industry
- Used as an active ingredient in anti-flatulent and digestive relief products to reduce bloating and gas discomfort.
- Incorporated in oral suspensions, tablets, and capsules to improve patient comfort by alleviating gastrointestinal gas.
- Acts as an anti-foaming agent in liquid formulations to enhance manufacturing efficiency and product stability.
Food Industry
- Employed as a food additive to prevent foaming in food processing and packaging, especially in beverages and sauces.
- Used in processing oils and fats to control foam formation during manufacturing.
Cosmetics and Personal Care
- Included in topical creams and lotions as an anti-foaming agent to improve texture and application.
- Used in shampoos and bath products to control foam consistency.
Industrial Applications
- Used in manufacturing processes requiring foam suppression in lubricants, paints, and coatings.
Secondary Uses
Laboratory and Analytical Uses
- Utilized in chemical laboratories to control foam during reactions and liquid handling.
Veterinary Medicine
- Used in veterinary formulations to relieve gas-related digestive discomfort in animals.
PRODUCT KEY FEATURES
Basic Identification Attributes
- Chemical Name (IUPAC): Polydimethylsiloxane and silica gel
- Common/Trade Name: Simethicone 100% USP 28
- CAS Number: 8050-81-5
- HS Code: 3819.00
- Synonyms: Dimethicone copolyol, Silicone anti-foaming agent
Physical & Chemical Properties
- Physical State: Viscous liquid or gel
- Color & Odor: Clear to slightly opaque; odorless
- Solubility: Insoluble in water; soluble in organic solvents
- Density: Approx. 1.05 g/cm³
- Stability: Chemically stable under normal storage conditions
Safety & Hazard Attributes
- GHS Classification: Generally regarded as safe; low toxicity
- Toxicity: Non-toxic and non-irritant under recommended use conditions
- Exposure Limits: No specific occupational limits; follow general safety practices
Storage & Handling Attributes
- Storage Conditions: Store in tightly closed containers in a cool, dry place away from direct sunlight
- Container Type: Plastic or metal drums, bottles, or bulk containers
- Shelf Life: Typically 24 months if stored properly
- Handling Precautions: Use gloves and avoid inhalation of aerosols or mists
Regulatory & Compliance Attributes
- Complies with USP standards for pharmaceutical and food-grade products
- Approved by FDA and other regulatory agencies for use in food and drugs
- Manufactured in GMP-certified facilities
Environmental & Health Impact
- Biodegradability: Poorly biodegradable but considered environmentally safe at low concentrations
- Ecotoxicity: Low toxicity to aquatic organisms
- Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS
Safety Handling Precautions
- PPE Required: Gloves recommended; goggles if splashing is possible
- Handling Guidelines: Avoid inhaling aerosols; use in well-ventilated areas
- Storage Measures: Keep containers tightly closed and stored in a dry environment
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if respiratory irritation occurs
- Skin Contact: Wash with soap and water; seek medical advice if irritation develops
- Eye Contact: Rinse thoroughly with water for 15 minutes; get medical help if irritation persists
- Ingestion: Rinse mouth; seek medical help if discomfort occurs
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂ for surrounding fires
- Special Precautions: Use protective equipment to avoid exposure to fumes from other materials
- Hazardous Combustion Products: May produce silicon oxides and other fumes under combustion
Related products
Methyl Paraben
Methyl Paraben is a white to off-white crystalline powder widely used as an antimicrobial preservative in cosmetics, pharmaceuticals, and food products. It is a member of the paraben family of preservatives known for their effectiveness against a broad spectrum of bacteria and fungi. Methyl Paraben helps extend the shelf life of products by preventing microbial growth without affecting the product's texture or color.
Methyl Salicylate BP
Methyl Salicylate BP is a clear, colorless to pale yellow oily liquid with a characteristic strong, sweet, and minty odor. It is an organic ester commonly used for its analgesic, anti-inflammatory, and flavoring properties. Methyl Salicylate is widely used in pharmaceutical preparations, topical pain relief products, cosmetics, and as a fragrance ingredient.
Pineapple Enzyme Powder
Pineapple Enzyme Powder is a fine, light-colored powder derived from the fruit and stem of the pineapple (Ananas comosus), containing the proteolytic enzyme bromelain. It is produced via extraction and subsequent drying (usually spray or freeze-drying) to preserve enzymatic activity. Known for its protein-digesting, anti-inflammatory, and exfoliating properties, this enzyme is widely used across food, nutraceutical, cosmetic, and pharmaceutical industries.
Polyglycerol-10-Laurate
Polyglycerol-10-Laurate is a non-ionic, biodegradable surfactant and emulsifier derived from natural lauric acid and polyglycerol (with ten glycerol units). It is known for its excellent emulsifying, dispersing, and solubilizing properties, especially in oil-in-water systems. Commonly used in cosmetics, food, pharmaceuticals, and personal care products, it is valued for being mild, non-toxic, and suitable for sensitive applications, including baby care and oral care.
Polyvinyl Alcohol
Polyvinyl Alcohol is a synthetic, water-soluble polymer made by the hydrolysis of polyvinyl acetate. It is known for excellent film-forming, emulsifying, and adhesive properties. PVA is widely used across industries for applications requiring biodegradable, non-toxic, and flexible materials. It offers good chemical resistance, mechanical strength, and compatibility with other polymers and additives.
Povidone Iodine BP
Povidone Iodine BP is a water-soluble complex of iodine with the synthetic polymer polyvinylpyrrolidone (PVP). It acts as a broad-spectrum antiseptic effective against bacteria, fungi, viruses, and protozoa. Widely used in medical, pharmaceutical, and veterinary fields, Povidone Iodine provides sustained iodine release, minimizing irritation while offering rapid antimicrobial action. It is essential for wound care, surgical preparation, and infection control.
Shellac
Shellac is a natural resin secreted by the lac insect, primarily found in South Asia. It is processed into flakes or powder form and dissolved in alcohol to create a versatile film-forming agent. Shellac provides excellent adhesion, gloss, and moisture resistance, making it widely used as a wood finish, food glaze, and pharmaceutical coating. It is valued for its natural origin, biodegradability, and safe use in food and cosmetic applications.
