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Sulphamethoxazole BP
Sulphamethoxazole BP is a synthetic sulfonamide antibiotic widely used in human and veterinary medicine for treating bacterial infections. It acts by inhibiting bacterial synthesis of dihydrofolic acid, thereby preventing bacterial growth. It is commonly combined with trimethoprim for synergistic effects against a broad spectrum of bacteria. The British Pharmacopoeia (BP) grade guarantees pharmaceutical purity and quality, making it suitable for formulation into tablets, suspensions, and other dosage forms.
Sulphamethoxazole BP
Primary UsesÂ
- Human Medicine
- Antibacterial Agent: Used to treat urinary tract infections, respiratory tract infections, gastrointestinal infections, and certain opportunistic infections (e.g., Pneumocystis pneumonia).
- Combination Therapy: Frequently combined with trimethoprim (co-trimoxazole) to enhance antibacterial efficacy.
- Veterinary Medicine
- Antimicrobial Agent: Used to treat bacterial infections in livestock and companion animals, including respiratory, urinary, and soft tissue infections.
- Medicated Feeds: Included in veterinary feed additives to prevent and control bacterial diseases.
Secondary UsesÂ
- Research & Development
- Pharmaceutical Studies: Used in drug formulation research and studies on antibiotic resistance.
- Microbiological Research: Utilized in bacterial culture sensitivity testing.
- Public Health
- Prophylactic Use: Occasionally used for prophylaxis against certain infections in immunocompromised patients.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
- Common/Trade Name: Sulphamethoxazole BP
- CAS Number: 723-46-6
- HS Code: 2941.20.00
- Synonyms: Sulfamethoxazole, SMX
2. Physical & Chemical Properties
- Physical State: White to off-white crystalline powder
- Color & Odor: White; odorless or faint sulfur-like odor
- Melting Point: 169–172 °C
- Solubility: Slightly soluble in water; soluble in alkaline solutions and organic solvents such as ethanol
- Density: Approx. 1.4 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: May cause allergic skin reactions and hypersensitivity
- Toxicity: Moderate toxicity; avoid prolonged exposure
- Exposure Limits: No specific occupational limits; use proper industrial hygiene
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area protected from light and moisture
- Container Type: Sealed HDPE or glass containers
- Shelf Life: 24 months under proper storage conditions
- Handling Precautions: Avoid dust; use gloves and masks to prevent inhalation and skin contact
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Manufactured under Good Manufacturing Practices (GMP)
- Meets pharmaceutical regulatory requirements for human and veterinary use
6. Environmental & Health Impact
- Biodegradability: Limited biodegradability; degrades slowly under aerobic conditions
- Ecotoxicity: Potentially harmful to aquatic organisms; avoid release into the environment
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves, protective clothing, and dust masks recommended
- Handling Guidelines: Use in well-ventilated areas; avoid inhalation and skin contact
- Storage Measures: Keep containers tightly closed and dry
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms occur
- Skin Contact: Wash with soap and water; discontinue use if irritation develops
- Eye Contact: Flush with water for 15 minutes; seek medical care if irritation persists
- Ingestion: Rinse mouth; seek medical advice promptly
Firefighting Measures
- Fire Hazards: Combustible solid
- Extinguishing Media: Use water spray, foam, dry chemical, or COâ‚‚ extinguishers
- Hazardous Combustion Products: Carbon oxides, nitrogen oxides, sulfur oxides
Related products
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Cetirizine Dihydrochloride
Cetirizine Dihydrochloride is a second-generation antihistamine widely used to relieve allergy symptoms such as hay fever, urticaria (hives), and other allergic conditions. It is the dihydrochloride salt form of cetirizine, presenting as a white to off-white crystalline powder that is odorless or nearly odorless and slightly bitter in taste. Cetirizine Dihydrochloride acts as a selective antagonist of peripheral H1 histamine receptors, preventing the effects of histamine and thereby reducing allergic symptoms without causing significant sedation. It is a commonly prescribed active pharmaceutical ingredient (API) in oral tablets, syrups, and capsules.
Cetirizine Hydrochloride
Cetirizine Hydrochloride is a widely used second-generation antihistamine effective for treating allergic conditions such as allergic rhinitis, chronic urticaria, and other allergy symptoms. It is the hydrochloride salt form of cetirizine, existing as a white to off-white crystalline powder with a slightly bitter taste. Cetirizine HCl acts by selectively blocking peripheral H1 histamine receptors, thereby reducing allergic symptoms without significant sedation or central nervous system depression. It is commonly formulated into tablets, syrups, and capsules as an active pharmaceutical ingredient.
Doxycycline Hyclate BP
Doxycycline Hyclate BP is a broad-spectrum, semisynthetic tetracycline-class antibiotic available as the hemihydrate salt form of doxycycline. It is widely used in pharmaceutical formulations due to its high bioavailability, broad antibacterial activity, and favorable pharmacokinetic profile. The compound exhibits bacteriostatic action by inhibiting protein synthesis in susceptible bacteria, making it effective against a wide range of Gram-positive and Gram-negative organisms as well as atypical pathogens. It is typically supplied as a fine, white to off-white crystalline powder soluble in water and suitable for oral and parenteral dosage forms.
Ichthammol BP98
Ichthammol BP98, also known as ammonium bituminosulfonate, is a dark brown to black, viscous, sulfur-rich, semi-solid substance derived from the distillation of shale or bituminous rocks. It has a characteristic tar-like odor and is highly valued in pharmaceutical and dermatological applications for its anti-inflammatory, antiseptic, antipruritic (anti-itch), and keratolytic properties. Ichthammol penetrates deeply into the skin and soft tissues, helping to alleviate inflammation and promote healing. It is widely used in topical preparations for treating skin conditions such as eczema, psoriasis, boils, abscesses, and other dermatological infections.
Ivermectin BP Vet
Ivermectin BP Vet is a potent, broad-spectrum antiparasitic agent widely used in veterinary medicine. It belongs to the avermectin family and works by disrupting nerve and muscle function in parasites, leading to paralysis and death. Ivermectin is highly effective against a range of internal and external parasites, including gastrointestinal worms, lungworms, mites, lice, and certain ticks. Available in oral, injectable, and topical forms, it is trusted for use in livestock, poultry, and companion animals. Its reliable efficacy, wide safety margin, and ease of administration make it an essential treatment in animal health and parasite control programs.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Norfloxacin
Norfloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic used primarily to treat bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Norfloxacin is effective against various Gram-negative and some Gram-positive bacteria and is commonly used in urinary tract infections, prostatitis, and gastroenteritis.
