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Eyedrop Dropper Bottle
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Trisodium Citrate
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Trisodium Citrate is a high-purity, pharmaceutical-grade salt of citric acid, widely used for its buffering, alkalizing, and chelating properties. It is a white crystalline powder that dissolves readily in water, forming an alkaline solution. This compound is primarily utilized in pharmaceutical formulations as a buffering agent, anticoagulant, and alkalizer. It also finds extensive use in food, cosmetic, and industrial applications. The British Pharmacopoeia (BP) grade ensures compliance with stringent quality standards for medicinal and food-grade use.
Description
Trisodium Citrate
Primary Uses
- Pharmaceutical Industry:
- Used as a buffering agent in intravenous solutions, oral rehydration salts, and pharmaceutical preparations to maintain pH stability.
- Acts as an anticoagulant by chelating calcium in blood collection tubes and diagnostic applications.
- Used in formulations to alkalinize urine in treatment of urinary tract infections and kidney stones.
- Food Industry:
- Employed as an acidity regulator, sequestrant, and flavor enhancer in beverages, dairy products, canned foods, and confections.
- Functions as an emulsifier and preservative to improve texture and shelf life of processed foods.
Secondary Uses
- Cosmetics and Personal Care:
- Used as a pH adjuster and buffering agent in skin creams, lotions, and shampoos.
- Industrial Applications:
- Serves as a chelating agent in detergents and cleaning products to enhance cleaning efficiency by binding metal ions.
- Laboratory Use:
- Utilized as a reagent and buffer in biochemical and molecular biology research.
KEY PRODUCT FEATURES
1. Basic Key Attributes
- Chemical Name (IUPAC): Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
- Common/Trade Name: Trisodium Citrate BP 98%
- CAS Number: 6132-04-3
- HS Code: 2918.16.00
- Synonyms: Sodium citrate tribasic, trisodium citrate dihydrate (depending on hydration)
2. Physical & Chemical Properties
- Physical State: White crystalline powder or granules
- Color & Odor: White; odorless
- Melting Point: Decomposes above 300 °C
- Solubility: Highly soluble in water; insoluble in alcohol
- pH: Alkaline aqueous solution (pH ~8.5–9.5)
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under normal handling
- Toxicity: Low toxicity; generally recognized as safe (GRAS) in food and pharmaceuticals
- Exposure Limits: No specific occupational exposure limits; follow standard hygiene practices
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, and well-ventilated area, protected from moisture and contaminants
- Container Type: Sealed moisture-proof bags or drums
- Shelf Life: Typically 24 months when stored under recommended conditions
- Handling Precautions: Avoid dust formation and exposure to moisture
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Manufactured under Good Manufacturing Practices (GMP)
- Listed on regulatory inventories including TSCA, REACH, and FDA GRAS list
- Approved for use in pharmaceutical, food, and cosmetic products
6. Environmental & Health Impact
- Biodegradability: Biodegradable under aerobic conditions
- Ecotoxicity: Low toxicity to aquatic organisms
- Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS
Safety Handling Precautions
- PPE Required: Gloves, dust mask, and eye protection recommended during handling
- Handling Guidelines: Use adequate ventilation; avoid dust inhalation
- Storage Measures: Keep containers sealed and dry
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if respiratory symptoms occur
- Skin Contact: Wash with soap and water
- Eye Contact: Rinse with plenty of water for at least 15 minutes; seek medical help if irritation persists
- Ingestion: Rinse mouth; seek medical advice if adverse effects occur
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Use water spray, foam, or dry chemical extinguishers
- Hazardous Combustion Products: May emit carbon oxides upon decomposition
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