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Vitamin B1 (Mono Nitrate BP)
Vitamin B1 Mononitrate BP is a stable, synthetic derivative of vitamin B1 (thiamine) used extensively in pharmaceutical, nutraceutical, and food fortification applications. It serves as an essential nutrient involved in carbohydrate metabolism and nervous system function. The mononitrate form offers enhanced stability and bioavailability compared to pure thiamine, making it ideal for inclusion in tablets, capsules, powders, and fortified food products.
Vitamin B1 (Mono Nitrate BP)
Primary Uses
- Pharmaceutical Industry
- Nutritional Supplement: Used in oral tablets, capsules, and injectables to prevent or treat thiamine deficiency and related disorders such as beriberi and Wernicke-Korsakoff syndrome.
- Neurological Support: Incorporated in formulations supporting nerve health and energy metabolism.
- Food & Beverage Industry
- Fortification Agent: Added to flour, cereals, beverages, and other food products to enhance nutritional content and prevent deficiency.
- Nutraceuticals & Dietary Supplements
- Included in multivitamin and B-complex supplements to support overall health and metabolic function.
Secondary Uses
- Animal Nutrition
- Feed Additive: Supplemented in animal feed to improve growth, appetite, and neurological health in livestock and pets.
- Cosmetic Industry
- Skin Health: Occasionally used in topical formulations for promoting skin vitality and repair, though limited.
- Research & Development
- Used in biochemical and nutritional studies involving vitamin B1 metabolism and deficiency.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium mononitrate
- Common/Trade Name: Vitamin B1 Mononitrate BP
- CAS Number: 532-43-4
- HS Code: 2936.21.00
- Synonyms: Thiamine mononitrate, vitamin B1 nitrate
2. Physical & Chemical Properties
- Physical State: Fine, white to off-white crystalline powder
- Color & Odor: White to off-white; odorless or faint characteristic odor
- Solubility: Soluble in water and alcohol
- Melting Point: 210-214 °C (decomposes)
- Density: Approx. 1.5 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under normal use
- Toxicity: Low toxicity; safe within recommended dosages
- Exposure Limits: No specific occupational exposure limits established
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area away from light and moisture
- Container Type: Sealed bags or containers, moisture-proof packaging preferred
- Shelf Life: 24 months under proper storage conditions
- Handling Precautions: Avoid dust formation and inhalation; use PPE if necessary
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Manufactured under GMP conditions for pharmaceutical grade quality
- Approved for use in food fortification, dietary supplements, and pharmaceuticals
- Meets international regulatory requirements for vitamin B1 products
6. Environmental & Health Impact
- Biodegradability: Biodegradable and environmentally safe under normal conditions
- Ecotoxicity: Low environmental risk
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves and dust mask recommended during handling
- Handling Guidelines: Use in well-ventilated areas to minimize dust exposure
- Storage Measures: Keep container tightly closed and dry
First Aid Measures
- Inhalation: Move to fresh air; seek medical advice if symptoms persist
- Skin Contact: Wash with soap and water
- Eye Contact: Flush with water for 15 minutes; seek medical help if irritation persists
- Ingestion: Rinse mouth; seek medical advice if large amounts ingested
Firefighting Measures
- Fire Hazards: Not highly flammable but combustible
- Extinguishing Media: Use water spray, foam, or dry chemical extinguishers
- Hazardous Combustion Products: May produce carbon oxides and nitrogen oxides on burning
Related products
Carbocisteine AJI 92
Carbocisteine AJI 92 is a high-purity pharmaceutical-grade amino acid derivative, chemically known as S-carboxymethyl-L-cysteine. It is a white to off-white crystalline powder with a slightly sulfurous odor and is freely soluble in water. Carbocisteine functions primarily as a mucolytic agent—reducing the viscosity of mucus and promoting expectoration in respiratory tract infections. The "AJI 92" specification refers to its compliance with the purity standards established by Ajinomoto's amino acid quality benchmarks, ensuring it meets stringent pharmaceutical-grade quality control for active pharmaceutical ingredients (APIs). It is widely used in oral syrups, tablets, and granules in both human and veterinary medicine.
Diclofenac Sodium BP
Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) widely used for its potent analgesic, anti-inflammatory, and antipyretic properties. It is the sodium salt form of diclofenac, providing enhanced solubility and rapid absorption. Diclofenac Sodium BP (British Pharmacopoeia standard) ensures pharmaceutical-grade purity and compliance with stringent quality standards. It is commonly formulated in oral tablets, topical gels, injections, and ophthalmic preparations.
Diphenhydramine HCL BP
Diphenhydramine HCL BP is a first-generation antihistamine with potent anticholinergic, sedative, and antiemetic properties. It is commonly used to relieve symptoms associated with allergies, hay fever, the common cold, and motion sickness. Diphenhydramine HCL is a white crystalline powder, highly soluble in water, making it suitable for oral, topical, and injectable pharmaceutical formulations. Due to its ability to cross the blood-brain barrier, it causes sedation and is often used as a sleep aid and for managing Parkinson’s disease symptoms.
Ivermectin BP Vet
Ivermectin BP Vet is a potent, broad-spectrum antiparasitic agent widely used in veterinary medicine. It belongs to the avermectin family and works by disrupting nerve and muscle function in parasites, leading to paralysis and death. Ivermectin is highly effective against a range of internal and external parasites, including gastrointestinal worms, lungworms, mites, lice, and certain ticks. Available in oral, injectable, and topical forms, it is trusted for use in livestock, poultry, and companion animals. Its reliable efficacy, wide safety margin, and ease of administration make it an essential treatment in animal health and parasite control programs.
Levamisole Hcl BP2000
Levamisole Hcl BP2000 is a white to off-white crystalline powder, soluble in water, with anthelmintic and immunomodulatory properties. It is primarily used as a veterinary antiparasitic agent effective against gastrointestinal nematodes in livestock. Levamisole HCL BP2000 conforms to British Pharmacopoeia standards, ensuring high purity and quality for pharmaceutical and veterinary formulations. Beyond veterinary uses, it is also researched for immunostimulant properties in medical applications.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole BP
Metronidazole BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Piperazine Citrate BP
Piperazine Citrate BP is a pharmaceutical-grade anthelmintic compound used primarily for the treatment of intestinal worm infections, especially ascariasis (roundworms) and enterobiasis (pinworms). It works by paralyzing the worms, allowing them to be expelled naturally from the body through bowel movements. Piperazine Citrate is included in the British Pharmacopoeia (BP) and is known for its safety, efficacy, and wide use in both human and veterinary medicine.
