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Vitamin B2 (Riboflavin base)
Vitamin B2 Riboflavin base, commonly known as Riboflavin Base, is a water-soluble vitamin essential for energy production, cellular function, and metabolism of fats, drugs, and steroids. It is a vital component of coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which participate in numerous biological oxidation-reduction reactions. Riboflavin base is widely used in pharmaceuticals, food fortification, and dietary supplements.
Vitamin B2 (Riboflavin base)
Primary Uses
- Pharmaceutical Industry
- Nutritional Supplement: Used in tablets, capsules, and injections to prevent and treat riboflavin deficiency and related disorders such as ariboflavinosis.
- Supportive Therapy: Included in B-complex vitamin formulations to enhance metabolic and enzymatic functions.
- Food & Beverage Industry
- Fortification Agent: Added to cereals, dairy products, beverages, and infant formulas to improve nutritional value and prevent deficiencies.
- Nutraceuticals & Dietary Supplements
- Used in multivitamin and B-complex supplements to promote energy metabolism, skin, eye health, and overall wellness.
Secondary Uses
- Animal Nutrition
- Feed Additive: Supplemented in animal feed to support growth, reproductive health, and metabolic processes in livestock and pets.
- Cosmetics
- Ingredient in skin care products for its antioxidant properties and to support healthy skin.
- Research & Development
- Utilized in biochemical and clinical research focusing on vitamin metabolism and deficiency.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 7,8-Dimethyl-10-(D-riboflavanosyl)isoalloxazine
- Common/Trade Name: Riboflavin Base, Vitamin B2
- CAS Number: 83-88-5
- HS Code: 2936.21.00
- Synonyms: Riboflavin, Vitamin B2, Lactoflavin
2. Physical & Chemical Properties
- Physical State: Orange to reddish-orange crystalline powder
- Color & Odor: Orange-red; odorless to faint odor
- Solubility: Sparingly soluble in water; insoluble in organic solvents
- Melting Point: 280 °C (decomposes)
- Density: Approx. 1.6 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under normal conditions
- Toxicity: Low toxicity; safe within recommended dosages
- Exposure Limits: No specific occupational exposure limits established
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, dark place to prevent degradation by light
- Container Type: Sealed, light-protective containers
- Shelf Life: 24 months under proper storage conditions
- Handling Precautions: Avoid dust generation and exposure to light
5. Regulatory & Compliance Attributes
- Complies with USP, BP, and other relevant pharmacopeia standards
- Manufactured under GMP to ensure quality and safety
- Approved for use in pharmaceuticals, dietary supplements, and food fortification
- Meets international regulatory requirements
6. Environmental & Health Impact
- Biodegradability: Biodegradable under normal environmental conditions
- Ecotoxicity: Low environmental impact
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves and dust mask recommended during handling
- Handling Guidelines: Use adequate ventilation; avoid inhalation of dust
- Storage Measures: Keep containers tightly closed and protected from light
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if irritation persists
- Skin Contact: Wash thoroughly with soap and water
- Eye Contact: Flush with water for 15 minutes; seek medical help if irritation continues
- Ingestion: Rinse mouth; obtain medical advice if necessary
Firefighting Measures
- Fire Hazards: Combustible but not highly flammable
- Extinguishing Media: Water spray, foam, or dry chemical extinguishers
- Hazardous Combustion Products: May produce carbon oxides and nitrogen oxides upon combustion
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