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Zinc Pyrithione
Zinc Pyrithione is a high-purity antimicrobial and antifungal compound derived from the coordination of zinc with pyrithione (1-hydroxy-2-pyridinethione). It is widely used as an active ingredient in personal care formulations, industrial coatings, and materials preservation due to its broad-spectrum biocidal efficacy against bacteria, fungi, and algae. Its excellent thermal stability and compatibility with various systems make it ideal for diverse industrial and cosmetic applications.
Zinc Pyrithione
Primary Uses
- Personal Care & Cosmetics
- Anti-Dandruff Agent: Widely used in shampoos and scalp treatments to control dandruff and seborrheic dermatitis.
- Antifungal in Skin Products: Used in creams and lotions to treat fungal skin conditions like tinea and seborrheic dermatitis.
- Paints & Coatings Industry
- Dry Film Preservative: Protects painted surfaces from fungal and algal growth, especially in humid conditions.
- Marine Coatings: Used in anti-fouling marine paints to prevent biofilm formation on ship hulls and underwater structures.
- Plastics & Polymers
- Antimicrobial Additive: Integrated into plastic products, sealants, and silicone to prevent microbial colonization.
- Textiles
- Antibacterial Treatment: Used in technical and medical textiles for microbial control and odor resistance.
Secondary Uses
- Construction Materials
- Biocide in Sealants and Adhesives: Added to construction sealants to prevent mold and mildew.
- Industrial Water Systems
- Microbial Control Agent: Occasionally used in industrial water circuits to prevent microbial growth (under regulated conditions).
- Leather Treatment
- Preservative: Applied during leather processing to inhibit microbial degradation and mold formation.
- Agriculture (Restricted/Regulated)
- Fungicide (Specialty Applications): Under strict regulatory control, used in select applications to prevent fungal growth on surfaces or equipment.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc
- Common/Trade Name: Zinc Pyrithione
- CAS Number: 13463-41-7
- HS Code: 2930.90.99
- Synonyms: ZPT, Zinc Omadine, Zinci pyrithionis
2. Physical & Chemical Properties
- Physical State: Crystalline powder
- Color & Odor: White to pale yellow; faint odor
- Melting Point: ~240 °C (decomposes)
- Solubility: Poorly soluble in water; soluble in ethanol and surfactant systems
- pH (1% Suspension): ~6.5–8.0
- Density: ~1.8 g/cm³
3. Safety & Hazard Attributes
- GHS Classification:
- Harmful if swallowed
- Causes serious eye irritation
- Very toxic to aquatic life with long-lasting effects
- Toxicity: Moderately toxic; not for internal or long-term unregulated exposure
- Exposure Limits: Avoid inhalation of powder; handle with PPE
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, in tightly sealed containers away from direct sunlight and moisture
- Container Type: Fiber drums or HDPE containers with liners
- Shelf Life: 2 years under proper storage conditions
- Handling Precautions: Avoid dust generation and contact with eyes or skin
5. Regulatory & Compliance Attributes
- Approved by FDA, EU, and other regulatory bodies for limited concentrations in personal care products
- Complies with REACH and TSCA for industrial us
- Subject to maximum concentration limits in cosmetics (typically 0.3% in rinse-off products)
- Not for use in food or pharmaceutical products
- Manufactured under ISO 9001 and ISO 22716 (GMP for cosmetics, when applicable)
- Must meet biocidal product regulations (BPR) in the EU and FIFRA in the U.S.
6. Environmental & Health Impact
- Biodegradability: Slowly biodegradable under environmental conditions
- Ecotoxicity: Highly toxic to aquatic organisms; must not be released into waterway
- Bioaccumulation: Low to moderate potential; environmental monitoring recommended
Safety Handling Precautions
- PPE Required: Gloves, goggles, dust mask or respirator
- Handling Guidelines: Use local exhaust ventilation; avoid formation of airborne dust
- Storage Measures: Keep containers tightly sealed; label clearly
First Aid Measures
- Inhalation: Move to fresh air immediately; seek medical attention if breathing difficulties occur
- Skin Contact: Wash thoroughly with soap and water
- Eye Contact: Rinse cautiously with water for 15 minutes; consult a physician
- Ingestion: Rinse mouth with water; do not induce vomiting; seek medical help
Firefighting Measures
- Fire Hazards: Non-flammable; may release toxic fumes (sulfur oxides, zinc oxides) if heated excessively
- Extinguishing Media: Water spray, dry powder, CO₂
- Hazardous Combustion Products: Sulfur dioxide, zinc oxide fumes
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Alpha Arbutin
Alpha Arbutin is a biosynthetic active ingredient derived from hydroquinone and glucose. It is widely used in cosmetic and skincare formulations for its skin-brightening and spot-reducing properties. Alpha Arbutin inhibits tyrosinase, an enzyme involved in melanin production, thereby helping to reduce pigmentation, dark spots, and uneven skin tone. It is more stable and effective than its beta counterpart and is suitable for all skin types, including sensitive skin.
Ascorbic Acid
Ascorbic Acid, commonly known as Vitamin C, is a water-soluble vitamin and potent antioxidant essential for collagen synthesis, immune function, and protection against oxidative stress. It is widely used as a nutritional supplement, food preservative, and additive to enhance shelf life and nutritional value. Naturally present in citrus fruits and various vegetables, ascorbic acid is also important in pharmaceutical, cosmetic, and animal feed industries due to its health benefits and preservative qualities.
Benzoic Acid
Benzoic Acid is a white crystalline solid with a faint, pleasant odor, classified as a simple aromatic carboxylic acid. It is widely used as a food preservative, antimicrobial agent, and chemical intermediate. Naturally occurring in many plants, it is commercially produced through oxidation of toluene or extraction from natural sources. Benzoic acid is valued for its ability to inhibit the growth of mold, yeast, and certain bacteria, making it essential in food preservation and cosmetic formulations. It also serves as a precursor in the manufacture of various pharmaceuticals, dyes, and plasticizers.
Bronopol
Bronopol (2-Bromo-2-nitropropane-1,3-diol) is a water-soluble, white crystalline powder or granules with a slight odor. It is a synthetic antimicrobial agent widely used as a preservative in personal care products, pharmaceuticals, cosmetics, and industrial applications. Bronopol exhibits broad-spectrum bactericidal and fungicidal activity, making it effective against a wide range of microorganisms. It works by releasing active formaldehyde slowly, which disrupts microbial metabolism and reproduction.
Capsicum Oleoresin
Capsicum Oleoresin is a concentrated extract derived from the dried fruits of Capsicum annuum or Capsicum frutescens (chili peppers). It is a dark red to brownish oily liquid containing approximately 8% capsaicinoids—primarily capsaicin and dihydrocapsaicin—which are the primary pungent components. This oleoresin is widely used for its flavoring, coloring, medicinal, and irritant properties in the food, pharmaceutical, veterinary, and defense industries. It is produced by solvent extraction followed by standardization to achieve consistent pungency levels. The product is highly potent and must be handled with care due to its intense irritant nature.
L-Glutathione Reduced
L-Glutathione Reduced is a tripeptide composed of glutamine, cysteine, and glycine, present in cells as a vital antioxidant. It appears as a white to off-white crystalline powder and plays a key role in protecting cells from oxidative stress by neutralizing free radicals and reactive oxygen species. Reduced glutathione (GSH) is the active form that participates in cellular detoxification, immune support, and regeneration of other antioxidants. It is widely used in pharmaceutical, cosmetic, and food industries due to its potent antioxidant properties and skin-brightening effects.
Methyl Paraben
Methyl Paraben is a white to off-white crystalline powder widely used as an antimicrobial preservative in cosmetics, pharmaceuticals, and food products. It is a member of the paraben family of preservatives known for their effectiveness against a broad spectrum of bacteria and fungi. Methyl Paraben helps extend the shelf life of products by preventing microbial growth without affecting the product's texture or color.
