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Silk Proteins
Silk Proteins are hydrolyzed proteins derived from natural silk fibers, typically composed of fibroin and sericin. They are water-soluble, bioactive compounds known for their excellent film-forming, moisture-retaining, and conditioning properties. Silk proteins are widely used in cosmetics, personal care products, pharmaceuticals, and textiles due to their biocompatibility, smooth texture, and ability to penetrate and protect surfaces like skin, hair, and fabric.
Silk Proteins
Primary Uses
- Cosmetics & Personal Care
- Used in shampoos, conditioners, and hair treatments for softness, shine, and improved manageability.
- Included in skincare formulations (creams, serums, lotions) to enhance hydration and skin smoothness.
- Forms a breathable, protective film on skin and hair to retain moisture.
- Applied in anti-aging products due to its amino acid content and skin-rejuvenating properties.
- Used in soaps and body washes for a silky lather and reduced dryness.
- Textile Industry
- Acts as a conditioning and softening agent in fabric finishing treatments.
- Enhances the strength and smoothness of natural and synthetic textiles.
- Applied in luxury fabrics and garments to improve luster and hand feel.
- Pharmaceuticals
- Used as a bio-compatible film former in wound dressings and topical formulations.
- Acts as a carrier for active pharmaceutical ingredients in controlled-release drug systems.
- Included in ocular preparations and hydrogels for enhanced biocompatibility.
- Hair Care Products
- Strengthens hair shafts and reduces breakage by binding to keratin.
- Used in hair dyes and bleaches to protect hair from chemical damage.
Secondary Uses
- Biomedical Applications
- Investigated for use in tissue engineering, scaffolds, and regenerative medicine due to its structural properties.
- Used in biodegradable microcapsules for drug delivery.
- Nutraceuticals & Supplements
- Hydrolyzed silk peptides are marketed as dietary supplements for hair, skin, and nail health.
- Coatings & Films
- Used in biodegradable films and coatings for packaging sensitive materials.
- Acts as a protective coating for food and pharmaceutical tablets.
- Printing & Paper
- Added to specialty papers to enhance surface texture and durability.
- Used in art paper for premium finishes and moisture resistance.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Hydrolyzed fibroin and sericin proteins
- Common/Trade Name: Silk Proteins
- CAS Number: 96690-41-4 (for hydrolyzed silk protein)
- HS Code: 3504.00.00
- Synonyms: Hydrolyzed silk protein, silk amino acids, silk peptides
2. Physical & Chemical Properties
- Physical State: Liquid or powder (depending on form)
- Color & Odor: Pale yellow to amber (liquid), off-white (powder); faint characteristic odor
- Solubility: Soluble in water
- pH: Typically 4.5 – 7.5 (aqueous solution)
- Molecular Weight: Varies; silk peptides usually <10,000 Da
- Stability: Stable under normal storage conditions
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous
- Toxicity: Non-toxic and non-irritant at recommended concentrations
- Exposure Limits: No specific occupational exposure limits
- Allergenic Potential: Low, but patch testing is advised for sensitive individuals
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, protected from light and moisture
- Container Type: HDPE drums, fiber drums, or sealed foil bags (for powder)
- Shelf Life: 12–24 months if stored properly
- Handling Precautions: Use clean utensils to avoid contamination; avoid excessive heat
5. Regulatory & Compliance Attributes
- Complies with cosmetic regulations (e.g., EU Cosmetic Regulation, FDA Cosmetic Ingredient Review)
- Approved for use in personal care products under INCI: Hydrolyzed Silk
- Meets relevant purity standards for pharmaceutical excipients where applicable
- Produced in GMP-compliant or ISO-certified facilities (varies by supplier)
6. Environmental & Health Impact
- Biodegradability: Readily biodegradable
- Ecotoxicity: Low; safe for aquatic and terrestrial environments at typical use levels
- Bioaccumulation: Not expected
- Environmental Impact: Minimal when used in cosmetics or textiles; safe for rinse-off applications
Safety Handling Precautions
- PPE Required: Gloves and goggles recommended for bulk handling
- Handling Guidelines: Avoid inhalation of fine powders; ensure clean tools to prevent contamination
- Storage Measures: Keep containers tightly closed and stored in a dry environment
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms persist
- Skin Contact: Wash with soap and water; unlikely to cause irritation
- Eye Contact: Rinse with water; seek medical attention if irritation continues
- Ingestion: Rinse mouth; not expected to be harmful in small quantities
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Water spray, COâ‚‚, dry chemical, or foam
- Special Precautions: Use protective equipment if fire involves packaging or other combustible materials
- Hazardous Combustion Products: Carbon oxides, nitrogen oxides
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