Mebendazole USP ( Micronized white) Amaris Chemicals
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PHARMACEUTICAL GRADE USP GRADE

Mebendazole USP ( Micronized white)

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Mebendazole USP (Micronized White) is a pharmaceutical-grade anthelmintic agent used for the treatment of parasitic worm infections. The micronized white powder form offers enhanced bioavailability and better dispersion in pharmaceutical formulations. It is effective against a broad spectrum of intestinal parasites including roundworms, whipworms, hookworms, and pinworms. Mebendazole is commonly used in oral tablet and suspension preparations, ensuring efficient parasite eradication with minimal side effects.

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Description

Mebendazole USP ( Micronized white)

Primary Uses 

  1. Anthelmintic Treatment
  • Used in pharmaceutical formulations for the treatment of helminthic infections such as ascariasis, trichuriasis, enterobiasis, and hookworm infections.
  • Incorporated in oral tablets, chewable tablets, and suspensions for both human and veterinary medicine.
  1. Pharmaceutical Intermediate
  • Utilized in the manufacture of generic and branded anti-parasitic medications.

Secondary Uses

  1. Research and Development
  • Used in biomedical research to study antiparasitic drug mechanisms and efficacy.
  1. Veterinary Applications
  • Occasionally used in veterinary formulations for treating parasitic infections in animals.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): Methyl [5-(benzoyl)-1H-benzimidazol-2-yl] carbamate
  • Common/Trade Name: Mebendazole USP (Micronized White)
  • CAS Number: 31431-39-7
  • HS Code: 2933.69.90
  • Synonyms: Vermox; Anthelminthic; Mebendazole powder; Benzimidazole carbamate

2. Physical & Chemical Properties

  • Physical State: Fine white powder (micronized)
  • Color & Odor: White; odorless
  • Melting Point: 288 °C (decomposes)
  • Solubility: Slightly soluble in water; soluble in dimethylformamide and dimethyl sulfoxide (DMSO)
  • Particle Size: Micronized for improved dissolution and bioavailability

3. Safety & Hazard Attributes

  • GHS Classification: Not classified as hazardous under normal pharmaceutical handling
  • Toxicity: Low acute toxicity; safe when used as directed in formulations
  • Exposure Limits: Follow pharmaceutical manufacturing hygiene standards

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry place protected from light and moisture
  • Container Type: Supplied in airtight, moisture-resistant packaging
  • Shelf Life: Typically 2-3 years under recommended storage
  • Handling Precautions: Avoid inhalation of powder; use appropriate PPE in manufacturing

5. Regulatory & Compliance Attributes

  • Complies with USP (United States Pharmacopeia) standards for pharmaceutical use
  • Registered and approved by major drug regulatory authorities for human use

6. Environmental & Health Impact

  • Biodegradability: Not readily biodegradable; minimal environmental exposure expected
  • Ecotoxicity: Low environmental risk when disposed of properly
  • Bioaccumulation: Not expected
  • Carcinogenicity/Mutagenicity: Not classified as carcinogenic
SAFETY HANDLING PRECAUTIONS
  • PPE Required: Dust mask or respirator, gloves, and protective eyewear during handling
  • Handling Guidelines: Work in well-ventilated areas or under local exhaust ventilation
  • Storage Measures: Keep containers tightly closed and away from incompatible substances

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if symptoms develop
  • Skin Contact: Wash with soap and water; consult a physician if irritation occurs
  • Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek medical help if irritation persists
  • Ingestion: Rinse mouth; seek medical advice promptly if large amounts ingested

Firefighting Measures

  • Fire Hazards: Combustible under fire conditions; may produce toxic fumes
  • Extinguishing Media: Use dry chemical, foam, or carbon dioxide extinguishers
  • Special Precautions: Wear full protective gear and self-contained breathing apparatus
  • Hazardous Combustion Products: Carbon monoxide, carbon dioxide, and nitrogen oxides

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