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Polyethyl Glycol( PEG 6000)
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Polyethyl Glycol( PEG 6000) is a high-molecular-weight polymer derived from ethylene oxide. It appears as a white, waxy solid or flake and is non-toxic, water-soluble, and chemically stable. PEG 6000 is widely used in pharmaceuticals, cosmetics, food processing, industrial formulations, and biotechnology, valued for its lubricating, solubilizing, binding, and moisturizing properties. It is odorless and tasteless, making it suitable for sensitive formulations.
Description
Polyethylene Glycol (PEG 6000)
Primary Uses
- Food Industry
- Used as a processing aid, carrier, or anti-caking agent in food additives.
- May be found in confectionery coatings, chewing gums, and bakery items.
- Recognized as safe (GRAS) for indirect food contact applications.
- Industrial Applications
- Employed as a mold release agent and lubricant in plastic and rubber processing.
- Used as an anti-static and anti-dust agent in powder formulations.
- Functions as a dispersant and lubricant in textile and leather finishing.
- Biotechnology & Laboratory Use
- Commonly used for protein precipitation and DNA purification.
- Acts as a crowding agent in cell fusion and virus precipitation.
- Serves as a medium for enzyme storage and protein stabilization.
Secondary Uses
- Paints and Coatings
- Used to improve flow, leveling, and flexibility in water-based paints and coatings.
- Printing Inks & Toners
- Functions as a binder and viscosity regulator for better print quality and stability.
- Ceramics and Construction
- Acts as a binder and plasticizer in ceramic slurries and dry mix mortars.
- Improves workability and water retention.
- Agricultural Chemicals
- Used as a carrier and wetting agent in pesticide and fertilizer formulations.
- Adhesives and Sealants
- Improves flexibility and tack in hot-melt adhesives and sealant compositions.
KEY PRODUCT FEATURES
1. Basic Identification Attributes
- Chemical Name (IUPAC): Poly(oxy-1,2-ethanediyl), α-hydro-ω-hydroxy-
- Common/Trade Name: PEG 6000
- CAS Number: 25322-68-3
- HS Code: 3907.20.00 (Polyethylene glycol and derivatives)
- Synonyms: Polyethylene oxide; Macrogol 6000
2. Physical & Chemical Properties
- Physical State: Solid (flakes or powder)
- Color & Odor: White; odorless
- Solubility: Completely soluble in water and alcohol
- Melting Point: 55–63°C
- Molecular Weight: Approx. 6,000 g/mol
- Viscosity (25°C, 20% solution): 90–130 cP
- pH (5% solution): 4.5–7.5
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous
- Toxicity: Non-toxic; safe for topical, oral, and parenteral use
- Allergen Status: Hypoallergenic
- Inhalation: Low risk; avoid excessive dust exposure
4. Storage & Handling Attributes
- Storage Conditions: Store in a dry, cool, well-ventilated area away from moisture and heat
- Container Type: Typically supplied in 25kg kraft paper bags or fiber drums with liners
- Shelf Life: Up to 3 years under proper storage conditions
- Handling Precautions: Use gloves and dust mask during bulk handling; avoid contact with eyes
5. Regulatory & Compliance Attributes
- Complies with:
- USP/NF, Ph. Eur., JP (pharmaceutical grades)
- FDA (GRAS for food contact and excipient use)
- REACH and RoHS (industrial use)
- ISO 9001 certified production
6. Environmental & Health Impact
- Biodegradability: Biodegradable under aerobic conditions
- Ecotoxicity: Low ecological risk
- Bioaccumulation: Not expected
- Allergenic Potential: None
SAFETY HANDLING PRECAUTIONS
Safety Handling Precautions
- PPE Required: Gloves, safety glasses, dust mask (bulk use)
- Handling Guidelines:
- Minimize dust generation
- Avoid ingestion or eye contact
- Use in well-ventilated areas
- Storage Measures: Keep sealed in moisture-proof containers
First Aid Measures
- Inhalation: Move to fresh air; seek help if coughing or discomfort persists
- Skin Contact: Wash with water and mild soap
- Eye Contact: Rinse cautiously with water for 15 minutes
- Ingestion: Rinse mouth with water; generally non-toxic, but consult a physician if large amounts are ingested
Firefighting Measures
- Fire Hazards: Slightly combustible at high temperatures
- Flash Point: >200°C
- Extinguishing Media: Water spray, CO₂, dry chemical, or foam
- Special Precautions: Avoid dust cloud formation
- Hazardous Combustion Products: Carbon dioxide, carbon monoxide
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