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Magnesium Trisilicate BP
Magnesium Trisilicate BP is a fine, white to off-white, odorless powder used primarily as an antacid and adsorbent. It is a hydrated magnesium salt of orthosilicic acid with excellent acid-neutralizing capacity. Classified under the British Pharmacopoeia (BP), it meets pharmaceutical-grade purity standards. Its high surface area and adsorptive properties make it useful in treating gastrointestinal discomfort, as well as in various industrial and food applications. It is insoluble in water and alcohol but reacts slowly with dilute acids.
Magnesium Trisilicate BP
Primary Uses
- Pharmaceutical Industry
- Antacid Agent: Used in tablets and suspensions to neutralize stomach acid and relieve symptoms of indigestion, heartburn, and gastritis.
- GI Protectant: Forms a protective coating over the stomach lining, reducing irritation from gastric acids.
- Excipient: Functions as a bulking agent and diluent in pharmaceutical formulations.
- Food Industry
- Food Additive (E560): Acts as an anti-caking agent and stabilizer in powdered food products.
- Acid Neutralizer: Used in food processing where pH control is required.
- Cosmetic and Personal Care
- Adsorbent: Incorporated in face powders, deodorants, and other topical products to absorb moisture and oils.
- Thickening Agent: Provides texture and consistency in cream and lotion formulations.
- Industrial Applications
- Clarifying Agent: Used in oil and fat refining processes.
- Adsorbent: Applied in purification processes and as a filtering aid in chemical industries.
Secondary Uses
- Veterinary Medicine
- Used as an antacid and gastrointestinal aid for animals.
- Laboratory Applications
- Occasionally used in analytical chemistry as an adsorbent or buffering material.
- Home Remedies
- Occasionally used in DIY remedies for mild acid reflux or as a topical drying agent.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Magnesium trisilicate
- Common/Trade Name: Magnesium Trisilicate BP
- CAS Number: 14987-04-3
- HS Code: 2833.29.90
- Synonyms: Trisilicic acid magnesium salt; Magnesium silicate hydrate; Mg₂Si₃O₈·nH₂O
2. Physical & Chemical Properties
- Physical State: Fine powder
- Color & Odor: White to off-white; odorless
- Solubility: Insoluble in water and alcohol; slowly reacts with dilute acids
- pH (suspension in water): 9.5–10.5
- Density: Approx. 2.5 g/cm³
- Loss on drying: Typically < 15%
- Bulk Density: ~0.3 – 0.6 g/cm³
- Surface Area: High, contributes to its adsorptive properties
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous
- Toxicity: Low toxicity; safe for pharmaceutical and food use
- Exposure Limits: Avoid prolonged inhalation of dust
- Irritation: May cause mild respiratory or eye irritation in dust form
4. Storage & Handling Attributes
- Storage Conditions: Store in a tightly sealed container in a dry, cool, well-ventilated area
- Container Type: Food- or pharma-grade polyethylene drums or multi-ply paper bags
- Shelf Life: 2–3 years under recommended storage conditions
- Handling Precautions: Avoid creating dust; use PPE if handling in bulk
5. Regulatory & Compliance Attributes
- Complies with BP (British Pharmacopoeia), USP, and EP standards
- Approved as food additive E560 by FDA and EFSA
- REACH-registered for industrial and pharmaceutical use
6. Environmental & Health Impact
- Biodegradability: Inorganic compound—not biodegradable but environmentally stable
- Ecotoxicity: Low toxicity to aquatic and terrestrial environments
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
Safety Handling Precautions
- PPE Required: Dust mask or respirator, gloves, and safety goggles for bulk handling
- Handling Guidelines: Minimize dust generation; use in ventilated areas
- Storage Measures: Keep dry and tightly sealed; avoid contamination with acids
First Aid Measures
- Inhalation: Move to fresh air if inhaled; seek medical advice if symptoms persist
- Skin Contact: Wash with soap and water if irritation occurs
- Eye Contact: Rinse thoroughly with water for several minutes; consult physician if needed
- Ingestion: Non-toxic; rinse mouth and consult medical attention in case of large ingestion
Firefighting Measures
- Fire Hazards: Non-combustible
- Extinguishing Media: Use water spray, CO₂, dry chemical, or foam for nearby materials
- Special Precautions: Avoid inhalation of dust in fire situations
- Hazardous Combustion Products: None known; material is stable under normal fire conditions
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Hydrocortisone Base BP 93 Micro
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Ivermectin BP Vet
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Mepyramine Maleate BP
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Neomycin Sulphate BP Oral
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