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PHARMACEUTICAL GRADE USP GRADE

Salbutamol Sulphate BP

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Salbutamol Sulphate BP is a white to off-white crystalline powder widely used as a bronchodilator in the treatment of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. It works by relaxing the muscles in the airways, improving airflow and easing breathing. The British Pharmacopoeia (BP) grade ensures high purity and quality suitable for pharmaceutical formulations such as inhalers, tablets, and syrups.

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Description

Primary Uses

Pharmaceuticals
Used in oral, inhalation, and injectable formulations to relieve bronchospasm in asthma and COPD patients.

Administered as a short-acting beta-2 adrenergic receptor agonist for quick relief of respiratory symptoms.

Included in combination therapies with corticosteroids or other bronchodilators for maintenance treatment.

Veterinary Medicine
Employed to treat respiratory distress and bronchoconstriction in animals.

 

Secondary Uses

Research & Development
Used as a reference standard in analytical testing and formulation development of respiratory drugs.

Pharmaceutical Manufacturing
Utilized in formulation trials and bioequivalence studies of bronchodilator medications.

PRODUCT KEY FEATURES

Basic Identification Attributes
Chemical Name (IUPAC): (RS)-4-[2-(tert-Butylamino)-1-hydroxyethyl]benzene-1,2-diol sulfate (salt)

Common/Trade Name: Salbutamol Sulphate BP

CAS Number: 18559-94-9

HS Code: 2933.39

Synonyms: Albuterol sulfate, Ventolin sulfate

 

Physical & Chemical Properties
Physical State: Crystalline powder

Color & Odor: White to off-white; odorless

Solubility: Soluble in water, slightly soluble in alcohol

Melting Point: Approximately 220°C (decomposes)

Stability: Stable under recommended storage conditions

 

Safety & Hazard Attributes
GHS Classification: Not classified as hazardous under normal handling; may cause irritation

Toxicity: Low toxicity at therapeutic doses; overdose can cause side effects

Exposure Limits: Follow pharmaceutical handling guidelines

 

Storage & Handling Attributes
Storage Conditions: Store in a cool, dry place, protected from light and moisture

Container Type: Supplied in sealed pharmaceutical-grade packaging

Shelf Life: Typically 2–3 years under proper storage

Handling Precautions: Use gloves and mask to avoid inhalation or skin contact

 

Regulatory & Compliance Attributes
Complies with British Pharmacopoeia (BP) standards for purity and quality

Approved by major regulatory agencies for pharmaceutical use

 

Environmental & Health Impact
Biodegradability: Not readily biodegradable; handle waste according to regulations

Ecotoxicity: Low environmental risk if disposed of properly

Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

PPE Required: Gloves, mask, and eye protection recommended

Handling Guidelines: Avoid inhalation and prolonged skin contact; use in well-ventilated areas

Storage Measures: Keep containers tightly closed and stored in a dry environment away from light

 

First Aid Measures
Inhalation: Move to fresh air; seek medical attention if breathing difficulties occur

Skin Contact: Wash with soap and water; seek medical advice if irritation develops

Eye Contact: Rinse thoroughly with water for 15 minutes; get medical attention if irritation persists

Ingestion: Rinse mouth; seek medical help immediately

 

Firefighting Measures
Fire Hazards: Not highly flammable but may decompose on heating to produce toxic fumes

Extinguishing Media: Use water spray, foam, dry chemical, or CO₂

Special Precautions: Use protective clothing and self-contained breathing apparatus if necessary

Hazardous Combustion Products: Carbon oxides, nitrogen oxides, sulfur oxides

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