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Alpha Arbutin
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 Alpha Arbutin is a biosynthetic active ingredient derived from hydroquinone and glucose. It is widely used in cosmetic and skincare formulations for its skin-brightening and spot-reducing properties. Alpha Arbutin inhibits tyrosinase, an enzyme involved in melanin production, thereby helping to reduce pigmentation, dark spots, and uneven skin tone. It is more stable and effective than its beta counterpart and is suitable for all skin types, including sensitive skin.
Description
Primary Uses
Cosmetic & Skincare Industry
- Reduces hyperpigmentation, dark spots, and age spots in skin care products.
- Promotes even skin tone and radiant complexion.
- Used in serums, creams, lotions, masks, and spot treatments.
- Suitable for formulations targeting melasma and sunspots.
- Compatible with other actives like hyaluronic acid, niacinamide, and vitamin C.
Secondary Uses
Personal Care
- Incorporated in anti-aging and brightening treatments.
- Used in formulations for under-eye darkness and blemish care.
PRODUCT KEY ATTRIBUTES
- Key Attributes
- Basic Identification Attributes
- Chemical Name (IUPAC): 4-Hydroxyphenyl α-D-glucopyranoside
- Common/Trade Name: Alpha Arbutin
- CAS Number: 84380-01-8
- HS Code: 2938.90
- Molecular Formula: C12H16O7
- Synonyms: 4-Hydroxyphenyl-α-D-glucopyranoside, α-Arbutin
- Physical & Chemical Properties
- Physical State: Solid powder
- Color & Odor: White to off-white, odorless
- Melting Point: ~203°C (decomposes)
- Boiling Point: Not applicable (decomposes)
- Density: ~1.5 g/cm³
- Solubility: Soluble in water
- pH Level: 3.5–6.5 (1% solution)
- Safety & Hazard Attributes
- Hazard Class (GHS): Not classified as hazardous
- NFPA Ratings: Health 1, Flammability 0, Reactivity 0
- Exposure Limits: Not established; considered safe in cosmetic concentrations
- Reactivity: Stable under normal conditions
- Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, away from direct sunlight and humidity
- Container Type: Airtight, light-resistant containers
- Shelf Life: 2 years under recommended storage conditions
- Special Handling: Avoid contamination; use clean tools and containers
- Regulatory & Compliance Attributes
- FDA (USA): Permitted in cosmetic formulations
- EU (Cosmetics Regulation): Allowed in cosmetic use
- Hazard Symbols (GHS): None
- Transportation Restrictions: None
- Environmental & Health Impact
- Ecotoxicity: Low; no significant environmental hazard at cosmetic concentrations
- Persistence: Biodegradable
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
Biodegradability: Readily biodegradable in environmental conditions
SAFETY HANDLING
- Safety Handling Precautions
- Wear gloves and a mask when handling bulk powder.
- Avoid generating dust during transfer or mixing.
- Wash hands thoroughly after handling.
First Aid Measures
- Inhalation: Move to fresh air if irritation occurs; seek medical help if symptoms persist.
- Skin Contact: Wash with water and mild soap.
- Eye Contact: Rinse immediately with plenty of water; consult a physician if irritation continues.
- Ingestion: Not intended for ingestion; seek medical attention if consumed in large amounts.
Firefighting Measures
- Fire Hazards: Non-flammable, non-combustible
- Extinguishing Media: Use water spray, foam, COâ‚‚, or dry chemical for surrounding fire
Special Precautions: No special measures required
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