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Calcium D-Panthothenate

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Calcium D-Panthothenate is the calcium salt of D-pantothenic acid (vitamin B5), appearing as a white or off-white crystalline powder. It is a stable, water-soluble compound widely used as a dietary supplement and pharmaceutical ingredient to supply vitamin B5, essential for coenzyme A synthesis and normal metabolism of carbohydrates, proteins, and fats. Calcium D-Panthothenate supports adrenal function, wound healing, and nervous system health, and is frequently incorporated into multivitamins, nutritional supplements, fortified foods, and topical formulations.

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Description

Primary Uses 

  1. Pharmaceuticals & Nutritional Supplements

    • Used as a vitamin B5 source in dietary supplements and multivitamin formulations to prevent or treat pantothenic acid deficiency.

    • Incorporated in pharmaceutical products targeting metabolic support, adrenal insufficiency, and wound healing.

    • Included in vitamin B-complex preparations for overall nutritional balance.

  2. Food & Beverage Industry

    • Fortification agent in functional foods, energy drinks, and infant formulas to enhance nutritional value.

    • Used as a food additive and nutritional supplement ingredient in health foods.

  3. Cosmetics & Personal Care

    • Added to topical skin care products for its moisturizing, anti-inflammatory, and skin barrier-enhancing properties.

    • Utilized in hair care products to improve hair strength and scalp health.

Secondary Uses 

  1. Veterinary Medicine

    • Employed as a vitamin supplement in animal feeds and veterinary nutritional products.

  2. Research & Development

    • Used in biochemical and nutritional studies related to metabolism and coenzyme A biosynthesis.

 

PRODUCT KEY FEATURES

. Basic Identification Attributes

  • Chemical Name (IUPAC): Calcium (2R)-2,4-dihydroxy-3,3-dimethylbutanoate

  • Common/Trade Name: Calcium D-Panthothenate, Calcium Pantothenate

  • CAS Number: 137-08-6

  • HS Code: 2936.29.90

  • Molecular Formula: C18H32CaN2O10

  • Synonyms:

    • Calcium Pantothenate

    • Vitamin B5 Calcium Salt

    • Ca-D-Pantothenate

    • Calcium D-pantothenate USP

2. Physical & Chemical Properties

  • Physical State: Fine crystalline powder or granules

  • Color & Odor: White to off-white; odorless

  • Melting Point: Approx. 120–130°C (decomposes)

  • Boiling Point: Not applicable (decomposes)

  • Density: Approx. 1.5 g/cm³

  • Solubility: Soluble in water; sparingly soluble in ethanol

  • pH: Slightly alkaline in aqueous solution (pH ~6–8)

  • Stability: Stable under normal conditions; sensitive to light, moisture, and heat

3. Safety & Hazard Attributes

  • Hazard Class (GHS): Generally regarded as safe (GRAS); low toxicity

  • NFPA Ratings:

    • Health: 0

    • Flammability: 1

    • Reactivity: 0

  • Exposure Limits: No specific OSHA/ACGIH limits established

  • Toxicity: Low; non-toxic at recommended doses

  • Reactivity: Stable; avoid strong oxidizers and extreme pH

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry place, protected from light and moisture

  • Container Type: Airtight, moisture-resistant containers (e.g., HDPE or glass)

  • Shelf Life: Typically 2–3 years if stored properly

  • Special Handling: Use PPE if dusty; avoid inhalation and prolonged skin contact

5. Regulatory & Compliance Attributes

  • FDA Status: Approved as a dietary supplement ingredient and food additive (Vitamin B5 source)

  • Pharmacopoeia Compliance: Listed in USP, EP, and JP standards

  • Transportation: Not classified as hazardous

  • Waste Disposal: Dispose according to local regulations; non-hazardous

6. Environmental & Health Impact

  • Ecotoxicity: Minimal environmental impact

  • Persistence: Organic compound; biodegradable under normal conditions

  • Bioaccumulation: Not expected to bioaccumulate

  • Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic

  • Biodegradability: Biodegradable

 

SAFETY HANDLING PRECAUTIONS

Personal Protective Equipment (PPE):

  • Gloves

  • Protective goggles

  • Dust mask if powdery

Handling Measures:

  • Avoid inhaling dust

  • Handle in well-ventilated area

Storage Measures:

  • Keep container tightly closed

  • Protect from moisture and light

Hygiene Practices:

  • Wash hands after handling

  • Avoid eating or drinking during handling

 

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if irritation occurs

  • Skin Contact: Wash with soap and water; seek medical advice if irritation develops

  • Eye Contact: Rinse with plenty of water; consult physician if irritation persists

  • Ingestion: Rinse mouth; seek medical advice if large amounts ingested

 

Firefighting Measures

  • Fire Hazards: Combustible but not highly flammable

  • Extinguishing Media: Use water spray, foam, dry chemical, or COâ‚‚

  • Special Precautions: Firefighters should wear protective gear

  • Decomposition Products: May produce carbon oxides, nitrogen oxides under high heat

 

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