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Calcium Lactate Pentahydrate
Calcium Lactate Pentahydrate is a white, crystalline, odorless powder that is the calcium salt of lactic acid with five molecules of water of crystallization. It is moderately soluble in water and has a slightly alkaline pH in solution. Widely used as a calcium supplement in the pharmaceutical and food industries, it is known for its good bioavailability and safety profile. Calcium Lactate Pentahydrate is utilized to prevent and treat calcium deficiencies and plays a role in bone health, muscle function, and enzyme activity. It also finds applications as a food additive and firming agent.
Calcium Lactate Pentahydrate
Primary Uses
- Pharmaceuticals & Nutraceuticals
- Used as a calcium supplement for preventing and treating hypocalcemia, osteoporosis, and other calcium deficiency-related conditions.
- Incorporated in effervescent tablets, chewable tablets, capsules, and oral solutions.
- Utilized in antacid formulations for neutralizing stomach acid and supplementing calcium.
- Food Industry
- Acts as a firming agent in canned and frozen fruits and vegetables.
- Used as a food additive (E327) to enrich calcium content in food and beverages.
- Serves as an acidity regulator and buffering agent in food processing.
- Beverage Industry
- Added to fortified drinks and mineral water to enhance calcium content.
Secondary Uses
- Cosmetics & Personal Care
- Occasionally used in oral care products (mouthwashes, toothpaste) for remineralization and enamel protection.
- Agriculture
- Used as a calcium source in animal feed supplements to improve bone and teeth health in livestock.
- Industrial
- Used in some specialty coatings and adhesives as a calcium source or pH regulator.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Calcium 2-hydroxypropanoate pentahydrate
- Common/Trade Name: Calcium Lactate Pentahydrate
- CAS Number: 1590-87-0
- HS Code: 2915.99.90
- Molecular Formula: Ca(C3H5O3)2 · 5H2O
- Synonyms:
- Calcium dl-lactate pentahydrate
- Calcium lactic acid salt pentahydrate
- Calcium lactate hydrate
- Calcium 2-hydroxypropanoate pentahydrate
2. Physical & Chemical Properties
- Physical State: Crystalline powder or granules
- Color & Odor: White; odorless
- Melting Point: Decomposes around 230–260°C (loss of water before decomposition)
- Boiling Point: Not applicable (decomposes)
- Density: Approx. 1.54 g/cm³
- Solubility: Soluble in water (~9.3 g/100 mL at 20°C); insoluble in alcohol
- pH: Slightly alkaline (pH 6.5–8.0 in aqueous solution)
- Stability: Stable under normal conditions; sensitive to heat and moisture
3. Safety & Hazard Attributes
- Hazard Class (GHS): Not classified as hazardous
- NFPA Ratings:
- Health: 0
- Flammability: 1 (combustible dust)
- Reactivity: 0
- Exposure Limits: No specific OSHA/ACGIH limits; standard dust precautions apply
- Toxicity: Low toxicity; safe for human consumption at recommended dosages
- Reactivity: Stable; avoid strong oxidizers and acids
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, away from moisture and incompatible substances
- Container Type: Sealed plastic or paper bags with inner lining, drums, or boxes
- Shelf Life: Typically 2–3 years if stored properly
- Special Handling: Avoid dust formation; use PPE such as gloves and dust masks during handling
5. Regulatory & Compliance Attributes
- FDA Status: Generally recognized as safe (GRAS) for use as a food additive and dietary supplement
- Pharmacopoeia Compliance: Complies with USP, EP, and BP standards
- Transportation: Not regulated as hazardous material
- Waste Disposal: Dispose as non-hazardous waste according to local regulations
6. Environmental & Health Impact
- Ecotoxicity: Low; minimal environmental impact
- Persistence: Biodegradable under aerobic conditions
- Bioaccumulation: Not expected
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
- Biodegradability: Readily biodegradable
Safety Handling Precautions
Personal Protective Equipment (PPE):
- Gloves
- Dust mask or respirator (if dust is generated)
- Safety goggles
- Protective clothing
Handling Measures:
- Avoid dust inhalation and prolonged skin contact
- Use in well-ventilated areas
- Avoid moisture exposure to prevent caking
Storage Measures:
- Keep container tightly closed
- Store away from strong acids and oxidizers
- Maintain dry environment to prevent degradation
Hygiene Practices:
- Wash hands after handling
- Do not eat, drink, or smoke when handling the substance
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if respiratory irritation occurs
- Skin Contact: Wash skin with soap and water; seek medical advice if irritation develops
- Eye Contact: Rinse eyes thoroughly with water for 15 minutes; seek medical advice if irritation persists
- Ingestion: Generally safe; in case of large ingestion, seek medical advice
Firefighting Measures
- Fire Hazards: Combustible dust hazard when dispersed in air
- Extinguishing Media: Use water spray, foam, dry chemical, or CO₂
- Special Precautions: Avoid creating dust clouds; firefighters should wear protective gear and self-contained breathing apparatus (SCBA) if necessary
- Decomposition Products: May produce carbon monoxide, carbon dioxide, and calcium oxide upon combustion
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