Calcium Saccharin

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Calcium Saccharin is the calcium salt form of saccharin, a synthetic sweetener. It appears as a white to off-white crystalline powder with a sweet taste that is several hundred times sweeter than sucrose (table sugar). Calcium Saccharin is water-soluble and widely used as a non-nutritive sweetener in food and beverage products, pharmaceuticals, and oral care formulations. Due to its stability under heat and acidic conditions, it is ideal for baked goods and beverages. It serves as a sugar substitute for diabetic and calorie-restricted diets and is often used in combination with other sweeteners to improve taste profiles.

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Categories: Excipients, Nutraceutical Ingredients (pharmaceutical), Sweeteners Tags: Artificial sweetener, Calcium saccharin, White crystalline powder

Description

Calcium Saccharin Uses

Primary Uses

Food Industry

Used as a high-intensity, calorie-free sweetener in soft drinks, candies, baked goods, and other processed foods.
Serves as a sugar substitute for diabetic-friendly and low-calorie foods.
Enhances sweetness without contributing to tooth decay or calories.

Pharmaceuticals

Incorporated as a sweetening agent in tablets, syrups, and chewable medications to improve palatability.
Used in oral hygiene products like mouthwashes and toothpastes for a sweet taste without promoting dental caries.

Cosmetics and Personal Care

Added to oral care formulations such as toothpaste and mouth rinses for flavor enhancement.

Secondary Uses

Veterinary Medicine

Used as a sweetener in animal feed supplements to improve palatability.

Research

Studied in food science and nutrition for effects on metabolism and sweetener blends.

PRODUCT KEY FEATURES

Basic Identification Attributes

Chemical Name (IUPAC): Calcium 1,2-benzisothiazol-3(2H)-one-1,1-dioxide salt
Common/Trade Name: Calcium Saccharin
CAS Number: 6486-23-3
HS Code: 2924.29.90
Molecular Formula: C14H8CaN2O6S2
Synonyms:
- Calcium saccharin salt
- Saccharin calcium salt
- Calcium saccharinate

Physical & Chemical Properties

Physical State: Crystalline powder
Color & Odor: White to off-white; odorless
Melting Point: Approximately 222–225°C (decomposes)
Density: Approx. 1.75 g/cm³
Solubility: Soluble in water (about 1.4 g/100 mL at 20°C); insoluble in ethanol
pH (aqueous solution): Neutral to slightly alkaline (pH 6–8)
Stability: Stable under normal conditions; heat resistant; stable in acidic and neutral media

Safety & Hazard Attributes

Hazard Class (GHS): Not classified as hazardous; generally recognized as safe (GRAS) for food use
NFPA Ratings:
- Health: 0
- Flammability: 1
- Reactivity: 0
Exposure Limits: No specific OSHA/ACGIH limits; avoid dust inhalation
Toxicity: Low acute toxicity; non-carcinogenic and non-mutagenic according to regulatory authorities
Reactivity: Chemically stable; avoid strong oxidizers

Storage & Handling Attributes

Storage Conditions: Store in a cool, dry, well-ventilated area away from moisture and incompatible substances
Container Type: Airtight containers such as plastic or glass bottles or sealed drums
Shelf Life: Typically 2–3 years under proper storage conditions
Special Handling: Use PPE to avoid dust exposure; avoid inhalation and skin contact

Regulatory & Compliance Attributes

FDA Status: Approved as a food additive and sweetener (E954) in many countries
EFSA: Approved for use as a sweetener in the EU with established acceptable daily intake (ADI)
Transportation: Not classified as hazardous
Waste Disposal: Dispose according to local non-hazardous waste regulations

Environmental & Health Impact

Ecotoxicity: Low environmental impact; considered biodegradable
Persistence: Moderate persistence; breaks down in wastewater treatment
Bioaccumulation: Not expected to bioaccumulate
Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic by WHO and FDA

Biodegradability: Partially biodegradable under aerobic conditions

SAFETY HANDLING PRECAUTIONS

Personal Protective Equipment (PPE):

Gloves
Protective goggles
Dust mask or respirator (when handling powder)
Protective clothing

Handling Measures:

Avoid dust formation and inhalation
Work in well-ventilated areas
Use local exhaust ventilation if dust is generated

Storage Measures:

Keep container tightly closed
Store away from moisture and incompatible substances
Avoid exposure to direct sunlight and heat

Hygiene Practices:

Wash hands thoroughly after handling
Do not eat, drink, or smoke during handling

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if breathing difficulties occur
Skin Contact: Wash with soap and water; seek medical attention if irritation develops
Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical advice if irritation persists
Ingestion: Rinse mouth; seek medical advice if large quantities ingested or symptoms develop

Firefighting Measures

Fire Hazards: Combustible under fire conditions
Extinguishing Media: Use water spray, foam, dry chemical, or CO₂ as appropriate for surrounding fire
Special Precautions: Firefighters should wear full protective gear and self-contained breathing apparatus (SCBA) if necessary

Decomposition Products: May emit toxic gases such as sulfur oxides and nitrogen oxides under fire conditions