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Cetomacrogol PEG1000 (Ginonic CSA 20)
Cetomacrogol PEG (Ginonic CSA) is a polyethylene glycol-based nonionic surfactant and emulsifier with an average molecular weight of approximately 1000 Da. It appears as a white to off-white waxy solid or flakes with a neutral odor. This high-quality grade is widely used in cosmetic, pharmaceutical, and personal care formulations due to its excellent emulsifying, solubilizing, and moisturizing properties. Cetomacrogol PEG1000 (Ginonic CSA 20) facilitates stable oil-in-water emulsions, improves product texture and skin feel, and enhances the bioavailability of active ingredients. Its hydrophilic nature and compatibility with a wide range of ingredients make it a versatile additive in creams, lotions, ointments, and topical gels.
Cetomacrogol PEG1000 (Ginonic CSA 20)
Primary Uses
- Cosmetics & Personal Care
- Functions as a nonionic emulsifier and solubilizer in creams, lotions, and moisturizing gels.
- Provides skin conditioning and moisturizing effects by forming a hydrophilic film on the skin.
- Enhances texture, spreadability, and stability of oil-in-water formulations.
- Used in cleansing products to improve foaming and mildness.
- Pharmaceuticals
- Acts as an emulsifying agent and solubilizer in topical and oral pharmaceutical formulations.
- Serves as a base for ointments, creams, and suppositories, enhancing the delivery of active ingredients.
- Improves texture and viscosity in pharmaceutical creams and gels.
Secondary Uses
- Industrial Applications
- Used in lubricant formulations as a stabilizer and viscosity modifier.
- Employed in textile and paper industries as a wetting and dispersing agent.
- Food Industry
- Occasionally used as a processing aid or carrier in flavor encapsulation under regulatory compliance.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Polyethylene glycol 1000 (PEG 1000)
- Common/Trade Name: Cetomacrogol PEG1000 (Ginonic CSA 20)
- CAS Number: 25322-68-3
- HS Code: 3907.99.00
- Molecular Formula: (C2H4O)nH2O, where n corresponds to an average molecular weight of ~1000 Da
- Synonyms:
- PEG 1000
- Polyethylene glycol 1000
- Macrogol 1000
2. Physical & Chemical Properties
- Physical State: White to off-white waxy solid or flakes
- Color & Odor: White to pale; odorless or faintly characteristic odor
- Melting Point: Approximately 37–40°C (softens and melts)
- Boiling Point: Decomposes before boiling
- Density: ~1.13 g/cm³ at 20°C
- Solubility:
- Soluble in water, alcohols, and glycols
- Insoluble in hydrocarbons and oils
- Stability: Stable under normal conditions; hygroscopic
3. Safety & Hazard Attributes
- Hazard Class (GHS): Not classified as hazardous
- NFPA Ratings:
- Health: 0
- Flammability: 1
- Reactivity: 0
- Exposure Limits: No specific limits; generally considered safe for intended uses
- Toxicity: Low toxicity; widely accepted for use in cosmetics and pharmaceuticals
- Irritation Potential: Minimal; generally non-irritating to skin and eyes
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, and well-ventilated area away from moisture and heat
- Container Type: Sealed bags, drums, or pails with moisture-resistant liners
- Shelf Life: Typically 3 years if stored correctly
- Special Handling: Avoid dust formation; use PPE as appropriate
5. Regulatory & Compliance Attributes
- Cosmetic Regulatory Status: Approved globally for use in cosmetics and personal care products
- Pharmacopoeial Status: Complies with pharmacopoeial standards where applicable
- REACH Status: Registered
- Transportation: Not regulated as hazardous material
- Waste Disposal: Dispose in compliance with local and national regulations; biodegradable
6. Environmental & Health Impact
- Ecotoxicity: Low; biodegradable and environmentally benign
- Persistence: Biodegradable under aerobic conditions
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: No known carcinogenic or mutagenic effects
- Biodegradability: Readily biodegradable
Safety Handling Precautions
- PPE: Use gloves, protective eyewear, and dust masks when handling in powder form
- Handling: Ensure adequate ventilation; avoid inhalation of dust or vapors
- Storage: Keep containers tightly closed to prevent moisture ingress
- Hygiene: Wash hands after handling; avoid ingestion and contact with eyes
First Aid Measures
- Inhalation: Move to fresh air if dust inhaled; seek medical attention if respiratory symptoms develop
- Skin Contact: Wash thoroughly with soap and water; generally non-irritating
- Eye Contact: Rinse immediately with water for at least 15 minutes; seek medical advice if irritation persists
- Ingestion: Non-toxic in small amounts; seek medical advice if large quantities are ingested
Firefighting Measures
- Fire Hazards: Combustible at elevated temperatures
- Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
- Special Precautions: Firefighters should wear full protective equipment and self-contained breathing apparatus
- Decomposition Products: May release carbon monoxide, carbon dioxide, and other hazardous fumes when burned
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