Preservatives(food)
Flavor Enhancers
Acidulants
Sweeteners
Antioxidants
Colorants(food)
Nutraceutical Ingredients (food)
Nutrient Supplements
Emulsifiers
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Fragrances and Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Solvents(lab)
Chromatography Chemicals
Spectroscopy Reagents
microbiology-and-cell-culture-reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Fresh Herbs
Ground Spices
Whole Spices
Spice Blends
Dried Herbs
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders
Chloramphenicol Palmitate Micronised
Whatsapp Order
Chloramphenicol Palmitate Micronised is a micronized, lipophilic ester derivative of chloramphenicol, designed for improved solubility and bioavailability compared to the parent drug. It appears as a fine, white to off-white powder with enhanced surface area due to micronization. This antibiotic is widely used for oral formulations, particularly pediatric suspensions, due to its palatability and controlled release properties. Chloramphenicol Palmitate exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. Its ester form offers better stability and reduced bitterness, making it a preferred choice in pharmaceutical preparations.
Description
Chloramphenicol Palmitate Micronised Uses
Primary Uses
Pharmaceutical Industry
- Used as an active pharmaceutical ingredient (API) in oral antibiotic formulations such as suspensions and syrups.
- Preferred for pediatric use due to improved taste and ease of administration.
- Employed for treatment of serious bacterial infections including typhoid fever, meningitis, and respiratory tract infections.
- Used in veterinary medicine for similar bacterial infections in animals.
Formulation Benefits
- Micronization improves dissolution rate and bioavailability.
- The palmitate ester enhances lipophilicity and prolongs drug release, allowing sustained therapeutic levels.
Secondary Uses
Research & Development
- Used in pharmaceutical research for developing novel delivery systems and improving drug stability.
Veterinary Medicine
- Occasionally used in topical formulations for wound infections in animals.
PRODUCT KEY FEATURES
- Basic Identification Attributes
- Chemical Name (IUPAC): 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide palmitate
- Common/Trade Name: Chloramphenicol Palmitate Micronised
- CAS Number: 552-94-3
- HS Code: 2941.90.90
- Molecular Formula: C32H48Cl2N2O6
- Molecular Weight: 502.65 g/mol
- Synonyms:
- Chloramphenicol palmitate
- Chloramphenicol palmitate powder
- Physical & Chemical Properties
- Physical State: Fine white to off-white powder
- Color & Odor: White to off-white; odorless or faint medicinal smell
- Particle Size: Micronized, typically below 10 microns
- Melting Point: ~120–125°C
- Solubility:
- Slightly soluble in water
- Soluble in organic solvents like ethanol, chloroform, and acetone
- Stability: Stable under recommended storage conditions; sensitive to light and moisture
- Safety & Hazard Attributes
- Hazard Class (GHS): Harmful if swallowed; may cause blood disorders (use with medical supervision)
- NFPA Ratings:
- Health: 2
- Flammability: 1
- Reactivity: 0
- Exposure Limits: Use with proper ventilation; avoid inhalation of powder
- Toxicity: Can cause serious adverse effects including aplastic anemia; restricted for medical use only
- Reactivity: Chemically stable; avoid strong oxidizing agents
- Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, protected from light and moisture
- Container Type: Sealed, airtight containers, preferably amber-colored to protect from light
- Shelf Life: 2–3 years if stored properly
- Special Handling: Use PPE to avoid inhalation; handle in controlled environments to prevent contamination
- Regulatory & Compliance Attributes
- FDA Status: Approved for specific pharmaceutical uses under prescription
- Pharmacopoeia Compliance: USP, BP, EP standards for identity, purity, and potency
- REACH Status: Registered
- Transportation: Classified as non-hazardous for transport under pharmaceutical regulations
- Waste Disposal: Dispose as per medical/pharmaceutical waste regulations
- Environmental & Health Impact
- Ecotoxicity: Low environmental persistence; handle pharmaceutical waste responsibly
- Persistence: Biodegradable under environmental conditions
- Bioaccumulation: Not expected to bioaccumulate significantly
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic; use with medical guidance
Biodegradability: Biodegradable
SAFETY HANDLING PRECAUTIONS
-
Safety Handling Precautions
- PPE: Gloves, lab coat, dust mask or respirator during handling
- Handling: Avoid inhalation and contact with skin or eyes; use in well-ventilated areas
- Storage: Keep containers tightly closed and protected from light and moisture
- Hygiene: Wash hands thoroughly after handling; no eating or drinking during handling
First Aid Measures
- Inhalation: Move to fresh air immediately; seek medical advice if symptoms develop
- Skin Contact: Wash affected area with soap and water; seek medical advice if irritation occurs
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; consult a doctor if irritation persists
- Ingestion: Do not induce vomiting; seek immediate medical attention
Firefighting Measures
- Fire Hazards: Combustible powder; may decompose to toxic gases when heated
- Extinguishing Media: Use water spray, foam, dry chemical, or CO₂
- Special Precautions: Firefighters should wear protective gear and respiratory protection
- Decomposition Products: May release hydrogen chloride, nitrogen oxides, and carbon monoxide upon burning
Related products
Ellagic Acid
Ellagic Acid is a naturally occurring polyphenolic compound found in numerous fruits, nuts, and vegetables such as pomegranates, strawberries, raspberries, walnuts, and cranberries. It is a potent antioxidant known for its ability to scavenge free radicals and chelate metal ions. Due to its significant anti-inflammatory, anti-carcinogenic, and anti-viral properties, Ellagic Acid has gained extensive interest in pharmaceutical, nutraceutical, cosmetic, and food industries. It appears as a yellow to light brown crystalline powder, insoluble in water but soluble in organic solvents like ethanol and DMSO.
Guaiphenesin BP
Guaiphenesin BP is a white crystalline powder or granules with a faint characteristic odor, classified as an expectorant used primarily in pharmaceutical formulations to relieve chest congestion. It works by loosening and thinning mucus in the airways, making it easier to cough up and clear from the respiratory tract. It is widely utilized in cough syrups, tablets, and cold remedies. Recognized for its mucolytic and muscle-relaxant properties, Guaiphenesin is included in both prescription and over-the-counter medications worldwide.
Hydrocortisone Acetate
Hydrocortisone Acetate is a synthetic corticosteroid ester derived from hydrocortisone (cortisol). It is a white to off-white crystalline powder, practically insoluble in water but soluble in alcohol and acetone. This compound exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic properties, making it widely used in pharmaceutical and dermatological formulations. Hydrocortisone Acetate acts by modulating gene expression to reduce the production of inflammatory mediators, thereby alleviating symptoms in various inflammatory and autoimmune conditions.
Ichthammol BP98
Ichthammol BP98, also known as ammonium bituminosulfonate, is a dark brown to black, viscous, sulfur-rich, semi-solid substance derived from the distillation of shale or bituminous rocks. It has a characteristic tar-like odor and is highly valued in pharmaceutical and dermatological applications for its anti-inflammatory, antiseptic, antipruritic (anti-itch), and keratolytic properties. Ichthammol penetrates deeply into the skin and soft tissues, helping to alleviate inflammation and promote healing. It is widely used in topical preparations for treating skin conditions such as eczema, psoriasis, boils, abscesses, and other dermatological infections.
Iodine Crystals
Iodine Crystals are high-purity elemental iodine in solid crystalline form. These dark violet-black crystals have a characteristic pungent odor and sublime easily at room temperature, releasing violet iodine vapors. Iodine is a halogen element widely used for its antiseptic, oxidizing, and chemical reagent properties in pharmaceutical, industrial, and laboratory applications.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Piperazine Citrate BP
Piperazine Citrate BP is a pharmaceutical-grade anthelmintic compound used primarily for the treatment of intestinal worm infections, especially ascariasis (roundworms) and enterobiasis (pinworms). It works by paralyzing the worms, allowing them to be expelled naturally from the body through bowel movements. Piperazine Citrate is included in the British Pharmacopoeia (BP) and is known for its safety, efficacy, and wide use in both human and veterinary medicine.
