Isopropyl Myristate Extra Pure

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SHORT DESCRIPTION

Isopropyl Myristate Extra Pure is a high-purity ester derived from isopropyl alcohol and myristic acid, commonly used for its excellent solvent and emollient properties. It appears as a colorless to slightly yellow, oily liquid with a faint odor. In laboratory and cosmetic settings, it serves as a solvent and carrier for active ingredients, particularly in topical formulations, where it enhances skin absorption without leaving a greasy residue. Its purity makes it suitable for precise formulation work in pharmaceutical, cosmetic, and personal care research. Isopropyl Myristate is also used in the preparation of perfumes and as a penetration enhancer in transdermal drug delivery systems.

Description

USES

Primary Laboratory Uses:

  1. Solvent for Drug Delivery Studies:
    Widely used as a non-polar solvent and penetration enhancer in transdermal drug delivery experiments, especially in formulation labs. 
  2. Emollient in Cosmetic Formulation Research:
    Serves as a model emollient in laboratory studies focused on the development of creams, lotions, and topical formulations. 
  3. Carrier Compound in Fragrance and Oil Studies:
    Used to dissolve fragrances and essential oils in analytical research related to perfumery and personal care products. 

Secondary Laboratory Uses:

  1. Skin Permeation Experiments:
    Commonly used in dermatological and pharmaceutical research to evaluate skin absorption and diffusion rates of active compounds. 
  2. Standard in Stability Testing:
    Applied in experiments testing the stability of emulsions and cosmetic formulations under various environmental conditions. 
  3. Non-volatile Component in Controlled Release Systems:
    Studied in labs exploring slow-release delivery systems for pharmaceuticals or active ingredients.

 

KEY PRODUCT FEATURES

KEY ATTRIBUTES

1. Basic Identification Attributes

  • Product Name: Isopropyl Myristate 
  • Chemical Name: Propan-2-yl tetradecanoate 
  • Grade: Extra Pure 
  • Chemical Formula: C₁₇H₃₄O₂ 
  • Molecular Weight: 270.45 g/mol 
  • CAS Number: 110-27-0 
  • Appearance: Clear, colorless to pale yellow oily liquid 
  • Odor: Faint, characteristic ester odor 

2. Composition

  • Purity: ≥99% (Extra Pure grade) 
  • Main Component: Isopropyl Myristate 
  • Impurities: Trace esters or alcohols (very low in lab grade) 

3. Physical & Chemical Properties

  • Boiling Point: ~167 °C at 10 mmHg 
  • Melting Point: ~-5 °C 
  • Flash Point: ~145 °C (closed cup) 
  • Density: ~0.85 g/cm³ at 25 °C 
  • Solubility: Insoluble in water; miscible with alcohols, oils, and organic solvents 
  • Viscosity: Low to medium 
  • Stability: Stable under normal lab conditions 

4. Safety & Hazard Attributes

  • GHS Classification:
    Not classified as hazardous under normal laboratory use 
  • Hazard Statements: 
    • Not expected to be hazardous 
    • May cause mild skin or eye irritation with prolonged contact 
  • PPE Requirements: 
    • Lab coat 
    • Gloves (nitrile recommended) 
    • Safety goggles 
  • First Aid Measures: 
    • Skin Contact: Wash with soap and water 
    • Eye Contact: Rinse thoroughly with water for several minutes 
    • Inhalation: Move to fresh air (not volatile, low risk) 
    • Ingestion: Rinse mouth; seek medical advice if discomfort persists 
  • Fire Hazards: 
    • Combustible at high temperatures 
    • Use dry chemical, CO₂, or foam to extinguish 

5. Storage & Handling Attributes

  • Storage Conditions: 
    • Store in tightly closed container 
    • Keep in a cool, dry, well-ventilated place 
    • Protect from direct sunlight and strong oxidizers 
  • Handling Tips: 
    • Avoid contact with eyes 
    • Wash hands after use 
    • No special ventilation required under standard lab use 

6. Laboratory Applications

  • Primary Uses: 
    • Solvent and carrier in drug delivery systems 
    • Component in formulation testing (cosmetic and pharmaceutical) 
    • Penetration enhancer in transdermal delivery studies 
    • Used to dissolve lipophilic substances in experiments 
  • Secondary Uses: 
    • Emollient in in-vitro skin compatibility studies 
    • Standard in cosmetic stability and degradation testing 
    • Extraction solvent in certain fat or oil-based analysis 
    • Inert medium in controlled-release formulations 
SAFETY HANDLING PRECAUTIONS

SAFETY MEASURES

Personal Protective Equipment (PPE):

  • Wear a lab coat, nitrile gloves, and protective goggles. 
  • Use in a well-ventilated area or fume hood to prevent inhalation of vapors. 

Handling:

  • Avoid contact with skin and eyes. 
  • Do not inhale vapors or mist. 
  • Practice good hygiene—wash hands thoroughly after handling. 

Storage:

  • Store in a tightly sealed container in a cool, dry, and well-ventilated place. 
  • Keep away from heat sources, open flames, and incompatible materials like strong oxidizers. 

FIRST AID MEASURES

Inhalation:

  • Remove the person to fresh air. 
  • Get medical attention if symptoms persist. 

Skin Contact:

  • Wash with soap and water. 
  • Remove contaminated clothing. 
  • Seek medical advice if irritation or sensitization occurs. 

Eye Contact:

  • Rinse cautiously with water for several minutes. 
  • Remove contact lenses if present and easy to do. 
  • Seek medical attention if irritation persists. 

Ingestion:

  • Rinse mouth with water. 
  • Do not induce vomiting. 
  • Seek immediate medical advice. 

FIRE FIGHTING MEASURES

Flammability:

  • Combustible liquid—can catch fire if heated above its flash point. 

Extinguishing Media:

  • Use dry chemical, CO₂, or alcohol-resistant foam. 
  • Water spray may be used to cool exposed containers. 

Hazardous Combustion Products:

  • May produce carbon monoxide and carbon dioxide during combustion. 

Firefighter Protection:

  • Wear full protective clothing and self-contained breathing apparatus (SCBA). 
  • Keep unnecessary personnel away from the fire area.