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Magnesium Trisilicate BP
Magnesium Trisilicate BP is a fine, white to off-white, odorless powder used primarily as an antacid and adsorbent. It is a hydrated magnesium salt of orthosilicic acid with excellent acid-neutralizing capacity. Classified under the British Pharmacopoeia (BP), it meets pharmaceutical-grade purity standards. Its high surface area and adsorptive properties make it useful in treating gastrointestinal discomfort, as well as in various industrial and food applications. It is insoluble in water and alcohol but reacts slowly with dilute acids.
Magnesium Trisilicate BP
Primary Uses
- Pharmaceutical Industry
- Antacid Agent: Used in tablets and suspensions to neutralize stomach acid and relieve symptoms of indigestion, heartburn, and gastritis.
- GI Protectant: Forms a protective coating over the stomach lining, reducing irritation from gastric acids.
- Excipient: Functions as a bulking agent and diluent in pharmaceutical formulations.
- Food Industry
- Food Additive (E560): Acts as an anti-caking agent and stabilizer in powdered food products.
- Acid Neutralizer: Used in food processing where pH control is required.
- Cosmetic and Personal Care
- Adsorbent: Incorporated in face powders, deodorants, and other topical products to absorb moisture and oils.
- Thickening Agent: Provides texture and consistency in cream and lotion formulations.
- Industrial Applications
- Clarifying Agent: Used in oil and fat refining processes.
- Adsorbent: Applied in purification processes and as a filtering aid in chemical industries.
Secondary Uses
- Veterinary Medicine
- Used as an antacid and gastrointestinal aid for animals.
- Laboratory Applications
- Occasionally used in analytical chemistry as an adsorbent or buffering material.
- Home Remedies
- Occasionally used in DIY remedies for mild acid reflux or as a topical drying agent.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Magnesium trisilicate
- Common/Trade Name: Magnesium Trisilicate BP
- CAS Number: 14987-04-3
- HS Code: 2833.29.90
- Synonyms: Trisilicic acid magnesium salt; Magnesium silicate hydrate; Mg₂Si₃O₈·nH₂O
2. Physical & Chemical Properties
- Physical State: Fine powder
- Color & Odor: White to off-white; odorless
- Solubility: Insoluble in water and alcohol; slowly reacts with dilute acids
- pH (suspension in water): 9.5–10.5
- Density: Approx. 2.5 g/cm³
- Loss on drying: Typically < 15%
- Bulk Density: ~0.3 – 0.6 g/cm³
- Surface Area: High, contributes to its adsorptive properties
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous
- Toxicity: Low toxicity; safe for pharmaceutical and food use
- Exposure Limits: Avoid prolonged inhalation of dust
- Irritation: May cause mild respiratory or eye irritation in dust form
4. Storage & Handling Attributes
- Storage Conditions: Store in a tightly sealed container in a dry, cool, well-ventilated area
- Container Type: Food- or pharma-grade polyethylene drums or multi-ply paper bags
- Shelf Life: 2–3 years under recommended storage conditions
- Handling Precautions: Avoid creating dust; use PPE if handling in bulk
5. Regulatory & Compliance Attributes
- Complies with BP (British Pharmacopoeia), USP, and EP standards
- Approved as food additive E560 by FDA and EFSA
- REACH-registered for industrial and pharmaceutical use
6. Environmental & Health Impact
- Biodegradability: Inorganic compound—not biodegradable but environmentally stable
- Ecotoxicity: Low toxicity to aquatic and terrestrial environments
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
Safety Handling Precautions
- PPE Required: Dust mask or respirator, gloves, and safety goggles for bulk handling
- Handling Guidelines: Minimize dust generation; use in ventilated areas
- Storage Measures: Keep dry and tightly sealed; avoid contamination with acids
First Aid Measures
- Inhalation: Move to fresh air if inhaled; seek medical advice if symptoms persist
- Skin Contact: Wash with soap and water if irritation occurs
- Eye Contact: Rinse thoroughly with water for several minutes; consult physician if needed
- Ingestion: Non-toxic; rinse mouth and consult medical attention in case of large ingestion
Firefighting Measures
- Fire Hazards: Non-combustible
- Extinguishing Media: Use water spray, CO₂, dry chemical, or foam for nearby materials
- Special Precautions: Avoid inhalation of dust in fire situations
- Hazardous Combustion Products: None known; material is stable under normal fire conditions
Related products
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Carbocisteine AJI 92 is a high-purity pharmaceutical-grade amino acid derivative, chemically known as S-carboxymethyl-L-cysteine. It is a white to off-white crystalline powder with a slightly sulfurous odor and is freely soluble in water. Carbocisteine functions primarily as a mucolytic agent—reducing the viscosity of mucus and promoting expectoration in respiratory tract infections. The "AJI 92" specification refers to its compliance with the purity standards established by Ajinomoto's amino acid quality benchmarks, ensuring it meets stringent pharmaceutical-grade quality control for active pharmaceutical ingredients (APIs). It is widely used in oral syrups, tablets, and granules in both human and veterinary medicine.
Chlorpheniramine Maleate
Chlorpheniramine Maleate is a first-generation alkylamine antihistamine used primarily to relieve allergy symptoms by blocking H1 histamine receptors. It appears as a white or off-white crystalline powder, freely soluble in water and alcohol. Known for rapid onset and moderate duration of action, it’s widely formulated in pharmaceuticals. It also exhibits mild anticholinergic and sedative effects.
Lidocaine HCL BP
Lidocaine HCL BP is a white crystalline powder or granules that are highly soluble in water. It is a local anesthetic and antiarrhythmic agent widely used in medical and dental fields. Lidocaine HCL BP acts by blocking nerve signal transmission, providing rapid and effective numbing of targeted areas. It conforms to British Pharmacopoeia (BP) standards, ensuring pharmaceutical-grade purity and consistency. It is commonly formulated into injections, topical gels, creams, and patches for pain relief and arrhythmia treatment.
Mebendazole USP ( Micronized white)
Mebendazole USP (Micronized White) is a pharmaceutical-grade anthelmintic agent used for the treatment of parasitic worm infections. The micronized white powder form offers enhanced bioavailability and better dispersion in pharmaceutical formulations. It is effective against a broad spectrum of intestinal parasites including roundworms, whipworms, hookworms, and pinworms. Mebendazole is commonly used in oral tablet and suspension preparations, ensuring efficient parasite eradication with minimal side effects.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Metronidazole BP
Metronidazole BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Miconazole Nitrate BP
Miconazole Nitrate BP is a high-purity, pharmaceutical-grade antifungal agent conforming to British Pharmacopoeia (BP) specifications. It is widely used in the formulation of topical and oral pharmaceutical products for the treatment of fungal infections caused by dermatophytes and yeasts, including Candida species. Miconazole Nitrate functions by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes, leading to cell death.
This white to off-white crystalline powder is highly effective and exhibits broad-spectrum antifungal and some antibacterial activity. It is commonly utilized in creams, ointments, powders, and gel formulations.
