Oxyclozanide Vet BP
Oxyclozanide Vet BP is a veterinary anthelmintic effective mainly against liver fluke (Fasciola hepatica) and some intestinal flukes in ruminants such as cattle, sheep, and goats. It works by interfering with the parasite’s energy metabolism, leading to parasite death and improving animal health and productivity.
Oxyclozanide Vet BP
Primary Uses
- Liver Fluke Control in Ruminants
- Treats acute and chronic infections caused by Fasciola hepatica.
- Reduces liver damage and associated clinical symptoms (anemia, weight loss).
- Improves productivity (milk yield, weight gain) in infected animals.
- Control of Intestinal Trematodes
- Effective against Paramphistomum spp. and other rumen flukes.
- Helps maintain gastrointestinal health and digestion efficiency.
- Veterinary Anthelmintic Therapy
- Used as a stand-alone treatment for fluke infections in cattle and sheep.
- Administered orally in doses according to veterinary prescription.
Secondary Uses
- Preventive Deworming Programs
- Used strategically during high-risk seasons to prevent heavy fluke infestations.
- Reduces pasture contamination by minimizing parasite egg shedding.
- Combination Therapy
- Occasionally combined with other antiparasitic agents (e.g., albendazole) for broader parasite spectrum coverage.
- Goat and Other Ruminant Use
- Off-label use under veterinary supervision for fluke treatment in goats and other ruminants.
- Improvement of Meat and Dairy Quality
- By controlling parasitic infections, it helps improve overall animal health and product quality.
- Use in Mixed-Parasite Infections
- Helpful in farms where liver fluke infections occur alongside other gastrointestinal parasites, as part of integrated parasite management.
- Research and Diagnostic Uses
- Used in veterinary research to study fluke resistance and pharmacodynamics.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 2-[(4-Chlorophenyl)carbamoyl]-3,5-dichlorobenzoic acid
- Common/Trade Name: Oxyclozanide Vet BP
- CAS Number: 2272-92-8
- HS Code: 2933.79.90
- Synonyms: Oxyclozanide; Salicylanilide derivative
2. Physical & Chemical Properties
- Physical State: White to off-white crystalline powder
- Color & Odor: Odorless to mild characteristic odor
- Solubility: Slightly soluble in water; soluble in organic solvents such as ethanol and acetone
- Melting Point: Approximately 195–200 °C
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous; standard veterinary chemical precautions apply
- Toxicity: Low toxicity to mammals when used as directed
- Exposure Limits: Use protective equipment to avoid dust inhalation
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area away from direct sunlight
- Container Type: Supplied in sealed plastic or paper bags with liners
- Shelf Life: Typically 2 years if stored properly
- Handling Precautions: Avoid inhalation and prolonged skin contact; use gloves and dust mask if necessary
5. Regulatory & Compliance Attributes
- Complies with BP (British Pharmacopoeia) veterinary standards
- Approved for veterinary use under relevant national regulations
6. Environmental & Health Impact
- Biodegradability: Moderate biodegradability
- Ecotoxicity: Avoid release into the environment to prevent aquatic toxicity
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: No evidence of carcinogenic or mutagenic effects
Safety Handling Precautions
- PPE Required: Gloves, dust mask, and safety goggles recommended during handling
- Handling Guidelines: Use in well-ventilated areas; avoid inhaling dust and contact with skin and eyes
- Storage Measures: Keep containers tightly closed and away from incompatible substances
First Aid Measures
- Inhalation: Move affected person to fresh air; seek medical advice if symptoms develop
- Skin Contact: Wash skin thoroughly with soap and water; seek medical attention if irritation occurs
- Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; consult a doctor if irritation persists
- Ingestion: Do not induce vomiting; seek medical attention promptly
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Use water spray, foam, dry chemical, or CO₂ extinguishers as appropriate
- Special Precautions: Use standard protective firefighting gear
- Hazardous Combustion Products: May produce toxic fumes under fire conditions
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