Alpha Arbutin

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Alpha Arbutin is a biosynthetic active ingredient derived from hydroquinone and glucose. It is widely used in cosmetic and skincare formulations for its skin-brightening and spot-reducing properties. Alpha Arbutin inhibits tyrosinase, an enzyme involved in melanin production, thereby helping to reduce pigmentation, dark spots, and uneven skin tone. It is more stable and effective than its beta counterpart and is suitable for all skin types, including sensitive skin.

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Categories: Antioxidants(cosmetic), Excipients, Humectants, Nutraceutical Ingredients (pharmaceutical) Tags: Alpha arbutin, Anti-dark spot agent, Brightening serum ingredient, Skin Care Ingredient, Whitening cream additive

Description

Primary Uses
Cosmetic & Skincare Industry

Reduces hyperpigmentation, dark spots, and age spots in skin care products.
Promotes even skin tone and radiant complexion.
Used in serums, creams, lotions, masks, and spot treatments.
Suitable for formulations targeting melasma and sunspots.
Compatible with other actives like hyaluronic acid, niacinamide, and vitamin C.

Secondary Uses
Personal Care

Incorporated in anti-aging and brightening treatments.
Used in formulations for under-eye darkness and blemish care.

PRODUCT KEY ATTRIBUTES

Key Attributes
Basic Identification Attributes

Chemical Name (IUPAC): 4-Hydroxyphenyl α-D-glucopyranoside
Common/Trade Name: Alpha Arbutin
CAS Number: 84380-01-8
HS Code: 2938.90
Molecular Formula: C12H16O7
Synonyms: 4-Hydroxyphenyl-α-D-glucopyranoside, α-Arbutin

Physical & Chemical Properties

Physical State: Solid powder
Color & Odor: White to off-white, odorless
Melting Point: ~203°C (decomposes)
Boiling Point: Not applicable (decomposes)
Density: ~1.5 g/cm³
Solubility: Soluble in water
pH Level: 3.5–6.5 (1% solution)

Safety & Hazard Attributes

Hazard Class (GHS): Not classified as hazardous
NFPA Ratings: Health 1, Flammability 0, Reactivity 0
Exposure Limits: Not established; considered safe in cosmetic concentrations
Reactivity: Stable under normal conditions

Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place, away from direct sunlight and humidity
Container Type: Airtight, light-resistant containers
Shelf Life: 2 years under recommended storage conditions
Special Handling: Avoid contamination; use clean tools and containers

Regulatory & Compliance Attributes

FDA (USA): Permitted in cosmetic formulations
EU (Cosmetics Regulation): Allowed in cosmetic use
Hazard Symbols (GHS): None
Transportation Restrictions: None

Environmental & Health Impact

Ecotoxicity: Low; no significant environmental hazard at cosmetic concentrations
Persistence: Biodegradable
Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic

Biodegradability: Readily biodegradable in environmental conditions

SAFETY HANDLING

Safety Handling Precautions

Wear gloves and a mask when handling bulk powder.
Avoid generating dust during transfer or mixing.
Wash hands thoroughly after handling.

First Aid Measures

Inhalation: Move to fresh air if irritation occurs; seek medical help if symptoms persist.
Skin Contact: Wash with water and mild soap.
Eye Contact: Rinse immediately with plenty of water; consult a physician if irritation continues.
Ingestion: Not intended for ingestion; seek medical attention if consumed in large amounts.