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Ellagic Acid
Ellagic Acid is a naturally occurring polyphenolic compound found in numerous fruits, nuts, and vegetables such as pomegranates, strawberries, raspberries, walnuts, and cranberries. It is a potent antioxidant known for its ability to scavenge free radicals and chelate metal ions. Due to its significant anti-inflammatory, anti-carcinogenic, and anti-viral properties, Ellagic Acid has gained extensive interest in pharmaceutical, nutraceutical, cosmetic, and food industries. It appears as a yellow to light brown crystalline powder, insoluble in water but soluble in organic solvents like ethanol and DMSO.
Ellagic Acid
Primary Uses
- Pharmaceuticals & Nutraceuticals
- Utilized as an active ingredient for its antioxidant and anti-inflammatory effects.
- Employed in formulations aimed at cancer prevention and as adjunct therapy due to its anti-proliferative properties.
- Investigated for potential antiviral applications including HIV and herpes simplex viruses.
- Used in dietary supplements for general health and immune support.
- Cosmetics & Personal Care
- Incorporated in anti-aging skin care products for its ability to protect skin from oxidative damage and UV-induced aging.
- Used in formulations targeting hyperpigmentation and skin brightening due to its melanin synthesis inhibition.
- Acts as an anti-inflammatory agent soothing irritated or sensitive skin.
- Food Industry
- Applied as a natural antioxidant additive in food preservation to extend shelf life and prevent lipid peroxidation.
- Used as a functional ingredient in health foods, beverages, and supplements.
- Research & Analytical Uses
- Used in biochemical research to study antioxidant mechanisms and as a standard compound in polyphenol analysis.
Secondary Uses
- Agriculture
- Explored as a natural plant growth regulator and for potential pest resistance due to its antimicrobial properties.
- Biomedical Research
- Investigated in tissue engineering and regenerative medicine for its cell-protective effects.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
- Common/Trade Name: Ellagic Acid
- CAS Number: 476-66-4
- HS Code: 2934.99.99
- Molecular Formula: C₁₄H₆O₈
- Synonyms:
- 4,4',5,5',6,6'-Hexahydroxydiphenic acid dilactone
- 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione
2. Physical & Chemical Properties
- Physical State: Crystalline powder
- Color & Odor: Yellow to light brown; odorless
- Melting Point: Approximately 300°C (decomposes)
- Solubility: Insoluble in water; soluble in ethanol, methanol, DMSO, and alkaline solutions
- Stability: Stable under normal conditions; sensitive to strong acids and bases
3. Safety & Hazard Attributes
- Hazard Class (GHS): Not classified as hazardous
- Toxicity: Low toxicity; generally safe in topical and oral use at recommended doses
- Exposure Limits: Not established
4. Storage & Handling Attributes
- Storage Conditions: Store in cool, dry, dark place in tightly sealed containers
- Container Type: Glass or plastic bottles with airtight caps
- Shelf Life: 2–3 years if stored properly
- Handling Precautions: Avoid dust inhalation and prolonged skin contact
5. Regulatory & Compliance Attributes
- Approved as a dietary supplement ingredient in many regions
- Compliant with food safety and cosmetic regulations globally
6. Environmental & Health Impact
- Biodegradability: Biodegradable under environmental conditions
- Ecotoxicity: Low
- Bioaccumulation: Not expected
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
Safety Handling Precautions
PPE Required:
- Dust mask or respirator (for powder handling)
- Safety goggles
- Gloves (nitrile or latex)
- Protective clothing or lab coat
Handling Guidelines:
- Handle in well-ventilated areas
- Avoid dust generation and inhalation
- Avoid prolonged skin contact
- Use closed systems or local exhaust ventilation when available
Storage Measures:
- Keep container tightly closed
- Store away from strong oxidizers and bases
- Protect from light and moisture
Hygiene Practices:
- Wash hands after handling
- Do not eat, drink, or smoke in handling areas
- Clean spills promptly to avoid dust spread
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if irritation persists
- Skin Contact: Wash thoroughly with soap and water; seek medical attention if irritation develops
- Eye Contact: Rinse with plenty of water for 15 minutes; seek medical advice if irritation persists
- Ingestion: Rinse mouth; not expected to be toxic, but seek medical attention if large amounts ingested
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
- Special Precautions: Use standard protective equipment
- Decomposition Products: May emit carbon monoxide, carbon dioxide, and other organic vapors upon decomposition
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Calcium D-Panthothenate is the calcium salt of D-pantothenic acid (vitamin B5), appearing as a white or off-white crystalline powder. It is a stable, water-soluble compound widely used as a dietary supplement and pharmaceutical ingredient to supply vitamin B5, essential for coenzyme A synthesis and normal metabolism of carbohydrates, proteins, and fats. Calcium D-Panthothenate supports adrenal function, wound healing, and nervous system health, and is frequently incorporated into multivitamins, nutritional supplements, fortified foods, and topical formulations.
Citric Acid Anhydrous
Citric Acid Anhydrous is a white, crystalline organic acid widely used across food, pharmaceutical, cosmetic, and industrial sectors. It is the anhydrous form of citric acid, meaning it contains no water molecules in its crystal lattice, resulting in higher purity and more concentrated acidic properties compared to its monohydrate form. Derived from natural sources like citrus fruits or produced via microbial fermentation, citric acid anhydrous is valued for its sour taste, excellent chelating ability, and buffering capacity. It serves as a natural preservative, pH adjuster, antioxidant synergist, and cleaning agent, making it a versatile ingredient in many formulations.
Citric Acid Monohydrate
Citric Acid Monohydrate is a white, crystalline powder or granule form of citric acid containing one molecule of water per molecule of acid. It is a natural organic acid commonly derived from citrus fruits or produced by fermentation processes. Citric Acid Monohydrate is widely used as an acidulant, preservative, and chelating agent in various industries. Compared to the anhydrous form, it has a slightly lower acid concentration due to the water molecule but offers excellent solubility and stability. It is prized for its sour flavor, buffering capacity, and ability to bind metal ions, making it indispensable in food, pharmaceutical, cosmetic, and industrial applications.
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Dextrose Anhydrous BP Injectable is a sterile, highly purified crystalline form of glucose that serves as a critical energy source in intravenous therapy. It is widely used in parenteral nutrition, rehydration, and hypoglycemia management. The anhydrous form contains no water, allowing precise control of concentration in injectable solutions. Meeting British Pharmacopoeia (BP) standards, it ensures pharmaceutical-grade purity and sterility, suitable for direct injection or as a component in compounded IV fluids. It provides readily available carbohydrates metabolized to supply energy, regulate osmolarity, and maintain fluid-electrolyte balance in clinical care.
L-Glutathione Reduced
L-Glutathione Reduced is a tripeptide composed of glutamine, cysteine, and glycine, present in cells as a vital antioxidant. It appears as a white to off-white crystalline powder and plays a key role in protecting cells from oxidative stress by neutralizing free radicals and reactive oxygen species. Reduced glutathione (GSH) is the active form that participates in cellular detoxification, immune support, and regeneration of other antioxidants. It is widely used in pharmaceutical, cosmetic, and food industries due to its potent antioxidant properties and skin-brightening effects.
Magnesium Ascorbyl Phosphate
Magnesium Ascorbyl Phosphate (MAP) is a stable, water-soluble derivative of Vitamin C, combined with magnesium. It offers antioxidant benefits and skin-brightening effects with improved stability and lower irritation compared to pure ascorbic acid. Widely used in cosmetics and pharmaceuticals, MAP promotes collagen synthesis, reduces pigmentation, and protects skin from oxidative damage.
Nicotinamide BP
Nicotinamide BP, also known as niacinamide, is a water-soluble form of vitamin B3 (niacin). It is a vital nutrient involved in numerous cellular processes, including energy metabolism, DNA repair, and antioxidant activity. Widely used in pharmaceutical, cosmetic, and nutritional applications, Nicotinamide supports skin health, improves barrier function, and exhibits anti-inflammatory properties. It is commonly found in dietary supplements, skincare formulations, and medical treatments for various dermatological conditions.
Vitamin E Acetate Oily
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