Tripolidine HCL BP

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Tripolidine HCL BP is a high-purity pharmaceutical-grade antihistamine used primarily to treat allergic conditions. It acts as a selective H1 histamine receptor antagonist, helping to relieve symptoms such as itching, sneezing, nasal congestion, and hives by blocking the action of histamine. The British Pharmacopoeia (BP) grade ensures compliance with stringent quality standards required for medicinal use. Tripolidine HCL is commonly formulated into tablets and syrups for effective allergy management.

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Category: Active Pharmaceutical Ingredients (APIs) Tags: Antihistamine, API, First-Generation Antihistamine Pharmaceutical Industry, Triprolidine HCl BP, Triprolidine Hydrochloride

Description

Table of Contents

Tripolidine HCL BP

Primary Uses

Pharmaceutical Industry:

Active ingredient in antihistamine medications for treating allergic rhinitis, urticaria (hives), conjunctivitis, and other hypersensitivity reactions.
Used in formulations for seasonal allergies and chronic allergic conditions.

Secondary Uses

Combination Drug Formulations:

Often combined with decongestants, analgesics, or other cold and allergy medication components to provide multi-symptom relief.

Veterinary Medicine:

Utilized occasionally in veterinary formulations to manage allergic responses in animals.

Research & Development:

Used in pharmacological research to study histamine receptor antagonism and develop improved allergy therapeutics.

KEY PRODUCT FEATURES

1. Basic Key Attributes

Chemical Name (IUPAC): 1-(4-Methylphenyl)-4-(1-pyrrolidinyl)-2-pyridinamine hydrochloride
Common/Trade Name: Tripolidine HCL BP
CAS Number: 3587-57-5
HS Code: 2933.69.90
Synonyms: Tripolidine Hydrochloride

2. Physical & Chemical Properties

Physical State: Fine crystalline powder
Color & Odor: White to off-white; odorless
Melting Point: Approximately 190-192 °C
Solubility: Soluble in water and alcohol
Purity: Meets British Pharmacopoeia (BP) specifications

3. Safety & Hazard Attributes

GHS Classification: Not classified as hazardous under standard pharmaceutical handling
Toxicity: Low toxicity; overdose may cause sedation, dry mouth, or dizziness
Exposure Limits: Follow pharmaceutical industry safety standards

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry, and well-ventilated place away from direct sunlight and moisture
Container Type: Sealed, moisture-proof containers such as HDPE drums or bottles
Shelf Life: Typically 24 months under proper storage
Handling Precautions: Avoid dust inhalation and contact with skin or eyes

5. Regulatory & Compliance Attributes

Complies with British Pharmacopoeia (BP) standards
Produced under Good Manufacturing Practices (GMP) for pharmaceutical use
Registered with relevant regulatory authorities for medicinal applications

6. Environmental & Health Impact

Biodegradability: Not readily biodegradable; proper disposal recommended
Ecotoxicity: Limited data; avoid environmental release
Bioaccumulation: Not significant

SAFETY HANDLING FEATURES

Safety Handling Precautions

PPE Required: Use gloves, dust mask, and eye protection during handling
Handling Guidelines: Use adequate ventilation to minimize dust exposure
Storage Measures: Keep containers tightly closed and protected from moisture

First Aid Measures

Inhalation: Move to fresh air; seek medical advice if breathing difficulties occur
Skin Contact: Wash with soap and water thoroughly
Eye Contact: Rinse immediately with plenty of water; seek medical attention if irritation persists
Ingestion: Rinse mouth and seek immediate medical attention

Firefighting Measures

Fire Hazards: Combustible under fire conditions
Extinguishing Media: Use foam, dry chemical, or carbon dioxide extinguishers
Hazardous Combustion Products: Carbon oxides, nitrogen oxides