Tripolidine HCL BP
Tripolidine HCL BP is a high-purity pharmaceutical-grade antihistamine used primarily to treat allergic conditions. It acts as a selective H1 histamine receptor antagonist, helping to relieve symptoms such as itching, sneezing, nasal congestion, and hives by blocking the action of histamine. The British Pharmacopoeia (BP) grade ensures compliance with stringent quality standards required for medicinal use. Tripolidine HCL is commonly formulated into tablets and syrups for effective allergy management.
Tripolidine HCL BP
Primary Uses
- Pharmaceutical Industry:
- Active ingredient in antihistamine medications for treating allergic rhinitis, urticaria (hives), conjunctivitis, and other hypersensitivity reactions.
- Used in formulations for seasonal allergies and chronic allergic conditions.
Secondary Uses
- Combination Drug Formulations:
- Often combined with decongestants, analgesics, or other cold and allergy medication components to provide multi-symptom relief.
- Veterinary Medicine:
- Utilized occasionally in veterinary formulations to manage allergic responses in animals.
- Research & Development:
- Used in pharmacological research to study histamine receptor antagonism and develop improved allergy therapeutics.
1. Basic Key Attributes
- Chemical Name (IUPAC): 1-(4-Methylphenyl)-4-(1-pyrrolidinyl)-2-pyridinamine hydrochloride
- Common/Trade Name: Tripolidine HCL BP
- CAS Number: 3587-57-5
- HS Code: 2933.69.90
- Synonyms: Tripolidine Hydrochloride
2. Physical & Chemical Properties
- Physical State: Fine crystalline powder
- Color & Odor: White to off-white; odorless
- Melting Point: Approximately 190-192 °C
- Solubility: Soluble in water and alcohol
- Purity: Meets British Pharmacopoeia (BP) specifications
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under standard pharmaceutical handling
- Toxicity: Low toxicity; overdose may cause sedation, dry mouth, or dizziness
- Exposure Limits: Follow pharmaceutical industry safety standards
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, and well-ventilated place away from direct sunlight and moisture
- Container Type: Sealed, moisture-proof containers such as HDPE drums or bottles
- Shelf Life: Typically 24 months under proper storage
- Handling Precautions: Avoid dust inhalation and contact with skin or eyes
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Produced under Good Manufacturing Practices (GMP) for pharmaceutical use
- Registered with relevant regulatory authorities for medicinal applications
6. Environmental & Health Impact
- Biodegradability: Not readily biodegradable; proper disposal recommended
- Ecotoxicity: Limited data; avoid environmental release
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Use gloves, dust mask, and eye protection during handling
- Handling Guidelines: Use adequate ventilation to minimize dust exposure
- Storage Measures: Keep containers tightly closed and protected from moisture
First Aid Measures
- Inhalation: Move to fresh air; seek medical advice if breathing difficulties occur
- Skin Contact: Wash with soap and water thoroughly
- Eye Contact: Rinse immediately with plenty of water; seek medical attention if irritation persists
- Ingestion: Rinse mouth and seek immediate medical attention
Firefighting Measures
- Fire Hazards: Combustible under fire conditions
- Extinguishing Media: Use foam, dry chemical, or carbon dioxide extinguishers
- Hazardous Combustion Products: Carbon oxides, nitrogen oxides
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