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Vitamin B6 (Pyridoxine HCL)
Vitamin B6 Pyridoxine HCL, also known as Pyridoxine Hydrochloride, is a water-soluble form of vitamin B6 used extensively in the pharmaceutical, food, and feed industries. It is essential for protein metabolism, neurotransmitter synthesis, red blood cell formation, and immune function. As a stable and bioavailable form of B6, it is widely incorporated in dietary supplements, fortified foods, clinical nutrition, and animal feed.
Vitamin B6 (Pyridoxine HCL)
Primary Uses
- Pharmaceutical Industry
- Therapeutic Agent: Used in tablets, capsules, and injections to treat and prevent vitamin B6 deficiency, peripheral neuropathy, premenstrual syndrome, and certain types of anemia.
- Supportive Therapy: Administered alongside isoniazid or hydralazine to prevent drug-induced B6 deficiency.
- Neurological Health: Supports cognitive function and nerve health, particularly in elderly populations.
- Nutraceuticals & Dietary Supplements
- Multivitamins: Included in B-complex and energy formulas to support metabolism, reduce fatigue, and improve immune function.
- Prenatal Supplements: Common in formulations for pregnant women to prevent nausea and ensure fetal brain development.
- Food & Beverage Industry
- Food Fortification: Added to cereals, baby foods, energy bars, and beverages to enhance nutritional content.
Secondary Uses
- Animal Nutrition
- Feed Additive: Used to promote growth, feed efficiency, and immune support in poultry, swine, cattle, aquaculture, and pet food.
- Cosmetics & Personal Care
- Skin & Hair Care: Sometimes included in formulations for scalp health, dandruff control, and overall skin wellness due to its role in protein metabolism.
- Clinical & Hospital Nutrition
- Parenteral Nutrition: Incorporated into IV nutrition solutions for patients with malabsorption or undergoing long-term hospitalization.
- Biotechnological & Research Applications
- Enzyme Studies: Used in cell culture and microbial fermentation processes requiring pyridoxal phosphate-dependent enzyme activity.
- Vitamin Metabolism Research: Applied in studies related to amino acid metabolism and neurological development.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 5-hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride
- Common/Trade Name: Pyridoxine Hydrochloride, Vitamin B6 HCl
- CAS Number: 58-56-0
- HS Code: 2936.26.00
- Synonyms: Vitamin B6 HCl, Pyridoxine HCl, Adermine hydrochloride
2. Physical & Chemical Properties
- Physical State: Crystalline powder
- Color & Odor: White to off-white; odorless
- Solubility: Freely soluble in water; slightly soluble in alcohol
- Melting Point: 205–206 °C (with decomposition)
- Density: Approx. 1.5 g/cm³
- pH (1% solution): 2.3–3.0
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous
- Toxicity: Very low toxicity; well tolerated in normal doses
- Exposure Limits: No established occupational exposure limits
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place away from light and moisture
- Container Type: Airtight, light-resistant containers
- Shelf Life: 36 months under proper conditions
- Handling Precautions: Avoid contact with moisture; prevent dust accumulation
5. Regulatory & Compliance Attributes
- Complies with: USP, BP, EP, JP standards
- Manufactured under: GMP conditions
- Approved in: Human and veterinary pharmaceuticals, supplements, fortified foods
- Globally Registered: Listed in major pharmacopoeias and food additive registries
6. Environmental & Health Impact
- Biodegradability: Biodegradable under normal environmental conditions
- Ecotoxicity: Low hazard to aquatic and terrestrial environments
- Bioaccumulation: Not bioaccumulative
Safety Handling Precautions
- PPE Required: Dust mask, gloves, and eye protection recommended
- Handling Guidelines: Work in well-ventilated areas; minimize airborne dust
- Storage Measures: Keep tightly closed in a dry, light-protected environment
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms persist
- Skin Contact: Wash with soap and water
- Eye Contact: Flush thoroughly with water for 15 minutes
- Ingestion: Rinse mouth; consult physician if large amounts consumed
Firefighting Measures
- Fire Hazards: Not highly flammable, but combustible in powder form
- Extinguishing Media: Use water spray, CO₂, foam, or dry chemical
- Hazardous Combustion Products: Carbon oxides and nitrogen oxides may be produced during combustion
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