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Vitamin B6 (Pyridoxine HCL)

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Vitamin B6 Pyridoxine HCL, also known as Pyridoxine Hydrochloride, is a water-soluble form of vitamin B6 used extensively in the pharmaceutical, food, and feed industries. It is essential for protein metabolism, neurotransmitter synthesis, red blood cell formation, and immune function. As a stable and bioavailable form of B6, it is widely incorporated in dietary supplements, fortified foods, clinical nutrition, and animal feed.

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Description

Vitamin B6 (Pyridoxine HCL)

Primary Uses

  1. Pharmaceutical Industry
  • Therapeutic Agent: Used in tablets, capsules, and injections to treat and prevent vitamin B6 deficiency, peripheral neuropathy, premenstrual syndrome, and certain types of anemia.
  • Supportive Therapy: Administered alongside isoniazid or hydralazine to prevent drug-induced B6 deficiency.
  • Neurological Health: Supports cognitive function and nerve health, particularly in elderly populations.
  1. Nutraceuticals & Dietary Supplements
  • Multivitamins: Included in B-complex and energy formulas to support metabolism, reduce fatigue, and improve immune function.
  • Prenatal Supplements: Common in formulations for pregnant women to prevent nausea and ensure fetal brain development.
  1. Food & Beverage Industry
  • Food Fortification: Added to cereals, baby foods, energy bars, and beverages to enhance nutritional content.

Secondary Uses

  1. Animal Nutrition
  • Feed Additive: Used to promote growth, feed efficiency, and immune support in poultry, swine, cattle, aquaculture, and pet food.
  1. Cosmetics & Personal Care
  • Skin & Hair Care: Sometimes included in formulations for scalp health, dandruff control, and overall skin wellness due to its role in protein metabolism.
  1. Clinical & Hospital Nutrition
  • Parenteral Nutrition: Incorporated into IV nutrition solutions for patients with malabsorption or undergoing long-term hospitalization.
  1. Biotechnological & Research Applications
  • Enzyme Studies: Used in cell culture and microbial fermentation processes requiring pyridoxal phosphate-dependent enzyme activity.
  • Vitamin Metabolism Research: Applied in studies related to amino acid metabolism and neurological development.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): 5-hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride
  • Common/Trade Name: Pyridoxine Hydrochloride, Vitamin B6 HCl
  • CAS Number: 58-56-0
  • HS Code: 2936.26.00
  • Synonyms: Vitamin B6 HCl, Pyridoxine HCl, Adermine hydrochloride

2. Physical & Chemical Properties

  • Physical State: Crystalline powder
  • Color & Odor: White to off-white; odorless
  • Solubility: Freely soluble in water; slightly soluble in alcohol
  • Melting Point: 205–206 °C (with decomposition)
  • Density: Approx. 1.5 g/cm³
  • pH (1% solution): 2.3–3.0

3. Safety & Hazard Attributes

  • GHS Classification: Not classified as hazardous
  • Toxicity: Very low toxicity; well tolerated in normal doses
  • Exposure Limits: No established occupational exposure limits

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry place away from light and moisture
  • Container Type: Airtight, light-resistant containers
  • Shelf Life: 36 months under proper conditions
  • Handling Precautions: Avoid contact with moisture; prevent dust accumulation

5. Regulatory & Compliance Attributes

  • Complies with: USP, BP, EP, JP standards
  • Manufactured under: GMP conditions
  • Approved in: Human and veterinary pharmaceuticals, supplements, fortified foods
  • Globally Registered: Listed in major pharmacopoeias and food additive registries

6. Environmental & Health Impact

  • Biodegradability: Biodegradable under normal environmental conditions
  • Ecotoxicity: Low hazard to aquatic and terrestrial environments
  • Bioaccumulation: Not bioaccumulative
SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Dust mask, gloves, and eye protection recommended
  • Handling Guidelines: Work in well-ventilated areas; minimize airborne dust
  • Storage Measures: Keep tightly closed in a dry, light-protected environment

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if symptoms persist
  • Skin Contact: Wash with soap and water
  • Eye Contact: Flush thoroughly with water for 15 minutes
  • Ingestion: Rinse mouth; consult physician if large amounts consumed

Firefighting Measures

  • Fire Hazards: Not highly flammable, but combustible in powder form
  • Extinguishing Media: Use water spray, CO₂, foam, or dry chemical
  • Hazardous Combustion Products: Carbon oxides and nitrogen oxides may be produced during combustion

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