PVP K 30 USP

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PVP K 30 USP (Polyvinylpyrrolidone K-30) is a water-soluble polymer widely used in pharmaceutical and cosmetic formulations. It serves as a binder, stabilizer, and film-forming agent, known for its excellent adhesive properties and compatibility with a wide range of ingredients. PVP K 30 USP is characterized by its medium molecular weight, making it ideal for tablet binding, enhancing solubility of poorly soluble drugs, and providing viscosity control in liquid formulations. This grade complies with USP standards ensuring suitability for pharmaceutical use.

Description

 

Primary Uses

Pharmaceutical Industry
Used as a binder in tablet and capsule formulations to improve mechanical strength and cohesion of powders.

Acts as a solubilizing agent to enhance bioavailability of poorly water-soluble drugs.

Employed as a suspending agent in oral suspensions and syrups.

Functions as a film former in controlled-release and coating formulations.

Cosmetics and Personal Care
Used as a thickener and stabilizer in lotions, creams, shampoos, and hair sprays.

Acts as a film-forming agent in hair styling products and facial masks.

Enhances moisture retention and skin feel in topical formulations.

Food Industry
Utilized as a stabilizer and emulsifier in certain food products under regulatory approval.

Secondary Uses

Industrial Applications
Used as a protective colloid and dispersant in adhesives, inks, and paints.

Employed in the formulation of photographic chemicals.

Laboratory Uses
Acts as a matrix and stabilizer in biochemical and molecular biology applications.

PRODUCT KEY FEATURES

Basic Identification Attributes
Chemical Name (IUPAC): Poly(1-vinyl-2-pyrrolidone)

Common/Trade Name: PVP K 30 USP

CAS Number: 9003-39-8

HS Code: 3906.90.10

Synonyms: Polyvinylpyrrolidone K-30; Povidone K30

Physical & Chemical Properties
Physical State: Fine white to off-white powder

Solubility: Soluble in water and some polar solvents

Molecular Weight: Approximately 40,000 Da (K value 30)

pH (1% solution): 4.0 – 7.0

Odor & Color: Odorless or slight characteristic odor; white powder

 

Safety & Hazard Attributes
GHS Classification: Not classified as hazardous

Toxicity: Low toxicity; non-irritant under normal use

Exposure Limits: Follow occupational safety standards for dust control

Storage & Handling Attributes
Storage Conditions: Store in a cool, dry, well-ventilated area away from incompatible substances

Container Type: Supplied in sealed bags or drums

Shelf Life: 2–3 years if stored properly

Handling Precautions: Avoid dust generation; use protective masks and gloves when handling powder

 

Regulatory & Compliance Attributes
Complies with USP monograph for Polyvinylpyrrolidone

Generally Recognized As Safe (GRAS) for specified uses

Manufactured in GMP-certified facilities

 

Environmental & Health Impact
Biodegradability: Readily biodegradable under aerobic conditions

Ecotoxicity: Low toxicity to aquatic organisms

Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

PPE Required: Dust mask, gloves, and eye protection recommended

Handling Guidelines: Use in well-ventilated areas; minimize dust exposure

Storage Measures: Keep containers tightly closed and stored in a dry environment away from moisture

 

First Aid Measures
Inhalation: Move to fresh air; seek medical attention if respiratory discomfort occurs

Skin Contact: Wash with soap and water; seek medical advice if irritation develops

Eye Contact: Rinse with plenty of water for at least 15 minutes; seek medical attention if irritation persists

Ingestion: Rinse mouth; seek medical advice if large quantities are ingested

 

Firefighting Measures
Fire Hazards: Combustible dust may form explosive mixtures in air

Extinguishing Media: Use water spray, foam, dry chemical, or COâ‚‚

Special Precautions: Avoid dust accumulation; use respiratory protection and protective clothing

Hazardous Combustion Products: Carbon oxides, nitrogen oxides