Calcium D-Panthothenate Amaris Chemicals
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Calcium D-Panthothenate

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Calcium D-Panthothenate is the calcium salt of D-pantothenic acid (vitamin B5), appearing as a white or off-white crystalline powder. It is a stable, water-soluble compound widely used as a dietary supplement and pharmaceutical ingredient to supply vitamin B5, essential for coenzyme A synthesis and normal metabolism of carbohydrates, proteins, and fats. Calcium D-Panthothenate supports adrenal function, wound healing, and nervous system health, and is frequently incorporated into multivitamins, nutritional supplements, fortified foods, and topical formulations.

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Description

Calcium D-Panthothenate

Primary Uses 

  1. Pharmaceuticals & Nutritional Supplements
  • Used as a vitamin B5 source in dietary supplements and multivitamin formulations to prevent or treat pantothenic acid deficiency.
  • Incorporated in pharmaceutical products targeting metabolic support, adrenal insufficiency, and wound healing.
  • Included in vitamin B-complex preparations for overall nutritional balance.
  1. Food & Beverage Industry
  • Fortification agent in functional foods, energy drinks, and infant formulas to enhance nutritional value.
  • Used as a food additive and nutritional supplement ingredient in health foods.
  1. Cosmetics & Personal Care
  • Added to topical skin care products for its moisturizing, anti-inflammatory, and skin barrier-enhancing properties.
  • Utilized in hair care products to improve hair strength and scalp health.

Secondary Uses 

  1. Veterinary Medicine
  • Employed as a vitamin supplement in animal feeds and veterinary nutritional products.
  1. Research & Development
  • Used in biochemical and nutritional studies related to metabolism and coenzyme A biosynthesis.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): Calcium (2R)-2,4-dihydroxy-3,3-dimethylbutanoate
  • Common/Trade Name: Calcium D-Panthothenate, Calcium Pantothenate
  • CAS Number: 137-08-6
  • HS Code: 2936.29.90
  • Molecular Formula: C18H32CaN2O10
  • Synonyms:
    • Calcium Pantothenate
    • Vitamin B5 Calcium Salt
    • Ca-D-Pantothenate
    • Calcium D-pantothenate USP

2. Physical & Chemical Properties

  • Physical State: Fine crystalline powder or granules
  • Color & Odor: White to off-white; odorless
  • Melting Point: Approx. 120–130°C (decomposes)
  • Boiling Point: Not applicable (decomposes)
  • Density: Approx. 1.5 g/cm³
  • Solubility: Soluble in water; sparingly soluble in ethanol
  • pH: Slightly alkaline in aqueous solution (pH ~6–8)
  • Stability: Stable under normal conditions; sensitive to light, moisture, and heat

3. Safety & Hazard Attributes

  • Hazard Class (GHS): Generally regarded as safe (GRAS); low toxicity
  • NFPA Ratings:
    • Health: 0
    • Flammability: 1
    • Reactivity: 0
  • Exposure Limits: No specific OSHA/ACGIH limits established
  • Toxicity: Low; non-toxic at recommended doses
  • Reactivity: Stable; avoid strong oxidizers and extreme pH

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry place, protected from light and moisture
  • Container Type: Airtight, moisture-resistant containers (e.g., HDPE or glass)
  • Shelf Life: Typically 2–3 years if stored properly
  • Special Handling: Use PPE if dusty; avoid inhalation and prolonged skin contact

5. Regulatory & Compliance Attributes

  • FDA Status: Approved as a dietary supplement ingredient and food additive (Vitamin B5 source)
  • Pharmacopoeia Compliance: Listed in USP, EP, and JP standards
  • Transportation: Not classified as hazardous
  • Waste Disposal: Dispose according to local regulations; non-hazardous

6. Environmental & Health Impact

  • Ecotoxicity: Minimal environmental impact
  • Persistence: Organic compound; biodegradable under normal conditions
  • Bioaccumulation: Not expected to bioaccumulate
  • Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
  • Biodegradability: Biodegradable
SAFETY HANDLING PRECAUTIONS

Safety Handling precautions

Personal Protective Equipment (PPE):

  • Gloves
  • Protective goggles
  • Dust mask if powdery

Handling Measures:

  • Avoid inhaling dust
  • Handle in well-ventilated area

Storage Measures:

  • Keep container tightly closed
  • Protect from moisture and light

Hygiene Practices:

  • Wash hands after handling
  • Avoid eating or drinking during handling

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if irritation occurs
  • Skin Contact: Wash with soap and water; seek medical advice if irritation develops
  • Eye Contact: Rinse with plenty of water; consult physician if irritation persists
  • Ingestion: Rinse mouth; seek medical advice if large amounts ingested

Firefighting Measures

  • Fire Hazards: Combustible but not highly flammable
  • Extinguishing Media: Use water spray, foam, dry chemical, or CO₂
  • Special Precautions: Firefighters should wear protective gear
  • Decomposition Products: May produce carbon oxides, nitrogen oxides under high heat

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